Rectal cancer that later spread to the vagina

Patient Info: Anonymized, Female, 60s | Stage IV

Metastatic Site: vagina

The isolated vaginal metastasis was surgically removed and followed by another 12 cycles of chemotherapy.

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Emergency Repair of a Long-Term Perineal Hernia After Rectal Cancer Surgery

Patient Info: Anonymized, Female, 70+ | Stage IV

Metastatic Site: lungs

She lived with metastatic rectal cancer and received community palliative care after becoming too frail for further chemotherapy.

PubMed CentralRead more →

Stage III Colorectal Cancer: Anna's Survivor Story

Patient Info: Anna | Stage III

Anna remains under surveillance with scans and colonoscopies and reports No Evidence of Disease.

Our Cancer StoriesRead more →

Metastatic Right-Sided Colon Cancer With an NRG1 Fusion

Patient Info: Anonymized, Male, 60s | Stage IV

Biomarkers: KRAS mutation; POMK-NRG1 fusion

Metastatic Site: liver|lungs

He had persistent metastatic disease after 16 months of afatinib and entered a phase I trial in January 2020.

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Nearly 5 years without rectal cancer recurrence when a lung nodule proved to be infection

Patient Info: Anonymized, Male, 60s

He remained without rectal-cancer recurrence for nearly 5 years after diagnosis. A new lung nodule found in 2020 was surgically biopsied and proved to be Pneumocystis infection rather than metastasis or a new lung cancer.

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Stage III Colorectal Cancer: Hilmi's Patient Story

Patient Info: Hilmi | Stage III

Hilmi was still undergoing chemotherapy and remained focused on recovery while managing a stoma and treatment side effects.

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Stage III Colorectal Cancer: Kenneth's Patient Story

Patient Info: Kenneth | Stage III

About 2 years after diagnosis, Kenneth was still undergoing treatment for Stage III colorectal cancer in late 2023.

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Stage I Colorectal Cancer: Paul's Survivor Story

Patient Info: Paul | Stage I

Completed treatment and described the cancer as beaten, with the goal of continuing life without cancer.

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Colorectal Cancer: Percy's Survivor Story

Patient Info: Percy

Completed treatment and described the cancer as being in remission.

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Colon Cancer With an MLH1 Deletion and Lynch Syndrome

Patient Info: Anonymized, Male, Under 40 | Stage III

Biomarkers: dMMR with loss of MLH1 and PMS2. Familial MLH1 c.1057_1060delGCTG frameshift deletion identified; its clinical significance had not previously been reported.

The colon cancer progressed rapidly despite postoperative and second-line therapy, and he died from multiple organ failure one week after pembrolizumab was started.

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Stage IV Colorectal Adenocarcinoma: Kyle's Survivor Story

Patient Info: Kyle, Under 40 | Stage IV

Kyle was 19 months NED and off treatment after Stage IV colon adenocarcinoma, following about 30 months of chemotherapy and targeted therapy.

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Stage IV Colorectal Adenocarcinoma: Amanda's Patient Story

Patient Info: Amanda, Under 40 | Stage IV

She remains on ongoing treatment for Stage IV disease and describes the cancer as pretty stable while maintaining a good quality of life.

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Stage IV Colorectal Cancer: Maria's Patient Story

Patient Info: Maria | Stage IV

Metastatic Site: lungs

After colorectal cancer spread to the lungs, completed 6 months of chemotherapy and is being monitored with CT scans every 3 months.

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Stage III Colorectal Cancer: Cleo's Survivor Story

Patient Info: Cleo | Stage III

Cleo completed active treatment and reports that she is in remission more than 3 years after her February 2021 diagnosis.

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Colorectal Cancer: Angela's Survivor Story

Patient Info: Angela

Angela was declared cancer-free in March 2022 after surgery and 4 months of chemotherapy.

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Colon Cancer Survivor: "I Didn't Think I Had Symptoms, Diagnosed Stage 3B" | Shelley's Story

Patient Info: Shelley Brown, Female | Stage III

As of October 2020, Shelley was in remission / no evidence of disease several years after Stage IIIB sigmoid colon cancer treatment, with ongoing surveillance by scans, CEA, and colonoscopy.

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Stage III Colorectal Cancer: Ben's Survivor Story

Patient Info: Ben Simcox, Male, Under 40 | Stage III

As of September 2020, Ben was cancer-free for almost 3 years after treatment for rectal cancer with 3 positive lymph nodes, including chemotherapy, radiation, surgery and 6 additional months of chemotherapy.

Cleveland ClinicRead more →

Treatment-Related Inflammation Mimicked Metastatic Colon Cancer Recurrence

Patient Info: Anonymized, Male, 50s | Stage IV

Biomarkers: KRAS mutation

Metastatic Site: liver|peritoneum

Biopsy showed that new lymph-node, liver, and spleen findings were a treatment-related sarcoid-like reaction rather than recurrence, and 18 months of surveillance found no evidence of cancer.

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Colon Cancer Metastasis Found Inside a Thyroid Nodule

Patient Info: Anonymized, Male, 50s | Stage Metastatic/Advanced

Biomarkers: KRAS mutated; thyroid metastasis CDX2 positive and CK20 positive; PAX8/TG/TTF-1 negative

Metastatic Site: lungs|thyroid

Follow-up was planned after thyroid surgery, with no adjuvant treatment for the coexisting low-risk thyroid lesion.

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Stage IV Colorectal Cancer: Scott's Patient Story

Patient Info: Scott Sterling, 50s | Stage IV

Metastatic Site: liver

After nearly 2 years of treatment for Stage IV colorectal cancer, Scott was able to have his primary tumor removed in August 2020 and was recovering while the metastatic disease continued to be managed.

Dana-FarberRead more →

Stage III Colorectal Cancer: Allison's Survivor Story

Patient Info: Allison, Female, Under 40 | Stage III

As of August 2020, Allison reported no evidence of disease on follow-up scans while continuing survivorship care after rectal-cancer treatment.

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Stage III Colorectal Cancer: Brooks's Survivor Story

Patient Info: Brooks Bell, Female | Stage III

As of July 2020, Brooks had no cancer found during follow-up colonoscopy, though new polyps were removed or biopsied and repeat colonoscopy was recommended in 1 year because polyps appeared to return quickly.

Colorectal Cancer AllianceRead more →

Stage III rectal adenocarcinoma with concurrent intermediate-risk prostate cancer

Patient Info: Anonymized, Male, 60s

Biomarkers: Rectal cancer CEA was not elevated. Prostate cancer PSA was high before treatment and low after radiation.

The rectal tumor achieved pathologic complete response with no residual tumor and 0 of 13 lymph nodes involved. Surveillance CT at 10 months showed no local recurrence or distant metastasis, and PSA remained low 1 year after operation.

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Colon Cancer Stories: Barbara Majeski

Patient Info: Barbara Majeski, Female, 40s | Stage III

As of May 2020, Barbara was approaching the 5-year mark after Stage III colon cancer, with blood tests every 6 months and annual scans reported as good/clear.

The Patient StoryRead more →