Stage IIIA Right Breast Cancer Followed by a Late Radiation Nerve Injury

Patient Info: Anonymized, Female, 50s | Stage III

Imaging in January 2019 found no evidence of breast-cancer recurrence, although she had developed radiation-induced brachial plexopathy.

PubMed CentralRead more →

HER2-Positive Breast Cancer Linked to a Rare Immune-Related Neurological Syndrome

Patient Info: Anonymized, Female, 40s

Biomarkers: HER2-positive in both foci; one focus ER-negative/PR-positive with Ki-67 45%; second focus ER-negative/PR-negative with Ki-67 35%; anti-Yo antibodies positive in serum and CSF; tumour-susceptibility gene panel negative

At 1 year, she had completed trastuzumab, continued tamoxifen, and had no evidence of recurrent breast cancer; intensive rehabilitation improved her mobility, although balance and right-sided neurological deficits persisted.

PubMed CentralRead more →

Late Breast Skin Changes After Partial-Breast Radiation

Patient Info: Anonymized, Female, 50s

Mammography, ultrasound, MRI, and skin biopsy found no breast-cancer recurrence 13 years after treatment.

PubMed CentralRead more →

Lobular breast cancer later spread to the stomach, bone, neck and mediastinum

Patient Info: Anonymized, Female, 70+ | Stage IV

Biomarkers: ER-positive; PR-positive; HER2-negative

Metastatic Site: stomach|bone|neck|mediastinum

After gastric metastasis was diagnosed and later imaging showed bone, neck and mediastinal spread, her oral intake and health declined; she chose palliative care and died 7 months after the diagnostic endoscopy.

PubMed CentralRead more →

Lobular Breast Cancer Spread Into a Nasal Tumor

Patient Info: Anonymized, Female, 60s | Stage IV

Biomarkers: Metastatic lobular focus: ER 8/8; PR 8/8; HER2-negative; E-cadherin-negative.

Metastatic Site: liver; bone; right nasal cavity within an olfactory…

The nasal lesion was removed with no residual local disease on imaging, and capecitabine was restarted while oncology follow-up continued for metastatic breast cancer.

PubMed CentralRead more →

Stage IV Breast Cancer: Kirby's Patient Story

Patient Info: Kirby Lewis, Male | Stage IV

Biomarkers: ER-positive, PR-positive, HER2-negative

Metastatic Site: lung|spine

Kirby was living with metastatic breast cancer, and his most recent scans showed the right-lung tumor was stable with no signs of progression while he continued fulvestrant and palbociclib.

Early breast cancer followed 19 years later by a radiation-related breast sarcoma

Patient Info: Anonymized, Female, 70+ | Stage I

Biomarkers: Strongly ER-positive; strongly PR-positive.

The stage IA breast carcinoma remained disease-free for 19 years; a later right-breast mass was a separate radiation-induced sarcoma rather than recurrent carcinoma.

PubMed CentralRead more →

Stage IV Breast Cancer: Dan's Patient Story

Patient Info: Dan DiNardo, Male, 40s | Stage IV

Metastatic Site: Left femoral ball/hip; spine; lymph nodes; chest

As of January 2020, Dan was living with metastatic recurrent male breast cancer on ongoing hormone-blocking therapy plus a CDK4/6 inhibitor after surgery and hip radiation; his cancer had shown no growth for 1 year.

Cleveland ClinicRead more →

Metastatic ER-positive breast cancer complicated by osteonecrosis of the jaw

Patient Info: Anonymized, Female, 70+ | Stage IV

Biomarkers: ER-positive.

Metastatic Site: bone (sternum, spine, pelvis, and proximal femur)

After progressive metastatic bone disease and severe medication-related osteonecrosis of the jaw, she entered end-of-life care and died three weeks after discharge to a nursing home.

PubMed CentralRead more →

Stage II Breast Cancer: Jaidive's Survivor Story

Patient Info: Jaidive, Female, 40s | Stage II

Jaidive was declared cancer-free on 11 November 2021 after lumpectomy, chemotherapy, radiation therapy, and tamoxifen/hormone therapy for Stage II breast cancer, while continuing specialist appointments and medication.

Our Cancer StoriesRead more →

Breast Cancer Recurrence in the Liver Mimicking Cirrhosis

Patient Info: Anonymized, Female, 60s | Stage IV

Biomarkers: Original cancer: HER2-negative and PR-positive. Liver recurrence: ER-positive.

Metastatic Site: liver

The breast cancer recurred in the liver after 14 years, produced pseudocirrhosis and portal-hypertension complications, and she died from hepatorenal syndrome five weeks after presentation.

PubMed CentralRead more →

Stage IV Breast Cancer: Janet's Survivor Story

Patient Info: Janet Klein, Female | Stage IV

Metastatic Site: Bone: left iliac bone

Janet’s Stage 1 breast cancer later recurred and metastasized to the left iliac bone, but she had no sign of cancer from January 2010 onward while continuing palbociclib plus letrozole.

Unexpected Miscarriage During Tamoxifen Treatment for Breast Cancer

Patient Info: Anonymized, Female, 40s

Four years after mastectomy, she remained on tamoxifen and recent imaging of the opposite breast was normal.

PubMed CentralRead more →

Breast Cancer Arising in Ectopic Tissue in the Armpit

Patient Info: Anonymized, Female, 40s

Biomarkers: ER positive; PR positive; HER2 negative

A 43-year-old woman’s presumed axillary cyst proved to be hormone-receptor-positive breast cancer arising in ectopic breast tissue.

PubMed CentralRead more →

Stage II HR-Positive Breast Cancer: Cath's Survivor Story

Patient Info: Cath, Female, 60s | Stage II

Biomarkers: ER-positive; PR-positive; HER2-negative

Cath was declared cancer-free in June 2024 after Stage II luminal A ER-positive/PR-positive/HER2-negative breast cancer treated with surgery, radiation, and hormone therapy, though she continued to manage long-term side effects and recurrence fear.

Our Cancer StoriesRead more →

Breast Cancer: Ken's Survivor Story

Patient Info: Ken Gremling, Male, 70+

Ken's mastectomy removed all of the cancer, and his clinicians expected a full recovery while he continued tamoxifen.

Cleveland ClinicRead more →

Breast Cancer: Jane's Survivor Story

Patient Info: Jane Gremling, Female, 60s

Jane's mastectomy removed all of the cancer, and her clinicians expected a full recovery while she continued tamoxifen and prepared for reconstruction.

Cleveland ClinicRead more →

Breast Cancer Recurring 18 Years After Mastectomy

Patient Info: Anonymized, Female, 70+ | Stage Metastatic/Advanced

Metastatic Site: sternum|lungs|pleura|chest wall

She died during respiratory decline caused by both metastatic breast cancer in the lungs and a separate primary lung cancer.

PubMed CentralRead more →

Lobular Breast Cancer Spreading to an Eye Muscle

Patient Info: Anonymized, Female, 40s | Stage Metastatic/Advanced

Biomarkers: Hormone receptor-positive; HER2-negative; E-cadherin-negative; CK7-positive

Metastatic Site: bones|left superior oblique eye muscle

The eye-muscle metastasis entered complete local remission, while bone disease was stable after 6 months of weekly paclitaxel and denosumab.

PubMed CentralRead more →

Recurrent Breast Cancer Initially Mistaken for Organising Pneumonia

Patient Info: Anonymized, Female, 60s | Stage Metastatic/Advanced

Biomarkers: ER-positive and GATA3-positive atypical pleural-fluid cells

Metastatic Site: lungs

After 12 months of first-line hormone therapy for metastatic recurrence, she had significant clinical and radiological improvement and remained on treatment.

PubMed CentralRead more →

Breast cancer treatment alongside severe pemphigus vulgaris

Patient Info: Anonymized, Female, 50s

Breast-cancer endocrine treatment was ongoing while her pemphigus required a separate treatment strategy; she was followed for 18 months.

PubMed CentralRead more →

Stage II metaplastic breast cancer in a 47-year-old man

Patient Info: Anonymized, Male, 40s | Stage II

Biomarkers: ER 1%; PR negative; HER2 negative; E-cadherin positive; p63 positive; genetic testing reported no abnormal mutations

Two years after surgery he was doing well, with only occasional pain at the mastectomy site and a negative recent mammogram of the left breast.

PubMed CentralRead more →

Metastatic Breast Cancer With Liver Progression Treated Through Multiple Chemotherapy Lines

Patient Info: Anonymized, female, 40s | Stage IV

Biomarkers: Initial tumor: ER 90%, HER2 3+, Ki67 15%. Liver metastasis: ER 30%

Metastatic Site: pleura, liver

After several periods of response and later liver progression, she remained on active treatment with pegylated liposomal doxorubicin.

PubMed CentralRead more →

Metastatic Breast Cancer With Bone and Liver Progression After Multiple Therapies

Patient Info: Anonymized, female, Under 40 | Stage IV

Biomarkers: Initial tumor: ER 80%, HER2 negative, Ki67 18%. Liver metastasis: ER 75%

Metastatic Site: bone, liver

After massive hepatic progression and liver failure, chemotherapy was stopped and she died on January 31, 2016.

PubMed CentralRead more →