Exercise Trainer Helps Detect Brain Metastases in a Woman With Long-Standing Metastatic Breast Cancer

Patient Info: Anonymized, female, 70+ | Stage IV

Biomarkers: ER-positive, PR-negative, HER2-negative

Metastatic Site: liver, bones, lymph nodes, kidney, brain

She died 5 months after the brain metastases were diagnosed, roughly 7 years after her original 2014 breast-cancer diagnosis.

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Stage IV Colorectal Cancer: Julie's Patient Story

Patient Info: Julie Flower, Female | Stage IV

Metastatic Site: Liver; lungs; lymph nodes; bones

As of September 2023, Julie had longstanding Stage IV colorectal cancer but a strong clinical-trial response after about 2.5 years on trial, with possible first no-evidence-of-disease assessment expected soon but not confirmed in this record.

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BRCA2-Mutated Metastatic Lung Adenocarcinoma Controlled for 30 Months With Olaparib

Patient Info: Anonymized, female, 60s | Stage IV

Biomarkers: PD-L1-negative; BRCA2 mutation; ATM mutation; EGFR-negative; ALK-negative

Metastatic Site: brain

Olaparib provided about 30 months of disease control, and PET imaging remained overall stable when a separate new breast primary was found in February 2023.

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Stage IV Colorectal Cancer: Keith's Patient Story

Patient Info: Keith, Male, 40s | Stage IV

Metastatic Site: Liver; lymph nodes; lungs

As of September 2023, Keith was on third-line treatment for Stage IV colon cancer with lung metastases, small lung lesions under 1 cm, a low tumor marker after 2 rounds, and possible trial/transplant options after standard care.

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Stage IV Triple-Negative Breast Cancer: April's Patient Story

Patient Info: April Donaldson, Female, 40s | Stage IV

Biomarkers: Triple-negative breast cancer; BRCA1 positive

Metastatic Site: Lungs

As of September 2023, April was living with Stage IV metastatic triple-negative breast cancer in the lungs; scans were stable in February but showed growth again in July, and PARP inhibitor therapy was being planned.

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Stage IV Ovarian Cancer: Melbey's Patient Story

Patient Info: Melbey Segovia, Female | Stage IV

Melbey Segovia died on May 4, 2021, about 5 years and 3 months after her February 2016 diagnosis, after three relapses and hospice care.

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Stage IV HER2-Positive Colorectal Cancer: Brian's Patient Story

Patient Info: Brian Beck, 50s | Stage IV

Biomarkers: HER2-positive

Metastatic Site: liver

Brian was receiving tucatinib plus trastuzumab on a clinical trial and was working full time 4.5 years after his Stage IV diagnosis.

Stage IV Colorectal Cancer: Danielle's Patient Story

Patient Info: Danielle Archer, Female, 40s | Stage IV

Biomarkers: No genetic markers reported

Metastatic Site: Liver; lungs

As of August 2023, Danielle was living with Stage IV metastatic colon cancer involving liver and lung lesions that were stable on ongoing treatment and 3-month surveillance scans.

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Occult Metastatic Breast Cancer First Appears as a Sternal Mass

Patient Info: Anonymized, female, 60s | Stage IV

Biomarkers: ER-positive, PR-positive, HER2-negative; BRCA1/2 testing negative

Metastatic Site: sternum

More than 3 years after the sternal mass was first detected, imaging showed no active breast or chest-wall disease and the cancers were described as appearing in remission while she continued tamoxifen.

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From Fatigue to Stage 4 Colon Cancer in Months: Trevor Maxwell’s Story

Patient Info: Trevor Maxwell, Male, 40s | Stage IV

Metastatic Site: Liver

As of August 2023, Trevor was living with Stage IV metastatic colon cancer and continued to describe his prognosis as uncertain while focusing on mental health and community support for men with cancer.

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Stage IV Breast Cancer: Britney's Patient Story

Patient Info: Britney Beadle, Female, Under 40 | Stage IV

Metastatic Site: Bone; liver; brain; lungs

As of August 2023, Britney was living with Stage IV breast cancer on Enhertu every 21 days, with liver clear and bone/lung disease showing regression on the latest described scan.

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Stage IV Breast Cancer: Brittney's Patient Story

Patient Info: Brittney Beadle, Female, Under 40 | Stage IV

Metastatic Site: Bones; liver; brain; lungs

As of August 2023, Brittney was living with Stage IV breast cancer on ENHERTU every 21 days, with brain clear for 4.5 years, liver clear, and bone and lung disease regressing.

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Colorectal cancer causing severe hip/back pain and kidney swelling

Patient Info: Anonymized, Male | Stage IV

Biomarkers: MLH1, MSH2, MSH6 and PMS2 expression retained; metastatic cells CK20-

Metastatic Site: distant lymph nodes; left psoas muscle /…

He had active metastatic colorectal cancer with malignant psoas syndrome; his condition worsened after the second palliative FOLFOX cycle and chemotherapy was discontinued.

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Stage IV Colorectal Cancer: Jason's Survivor Story

Patient Info: Jason Randall; Amy Hart, Male; Female | Stage IV

Metastatic Site: Jason: tailbone recurrence/site described; Amy: not…

As of August 2023, Jason was almost 5 years into Stage IV colorectal cancer survivorship and living with a permanent colostomy after recurrence treatment; Amy was several years into Stage IIIB colorectal survivorship and living an active life with an ostomy.

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Stage IV Breast Cancer: Fadia's Survivor Story

Patient Info: Fadia, Female, Under 40 | Stage IV

Metastatic Site: Bone | Spleen | Lung | Liver | Brain

As of the August 2023 article update, Fadia had recovered after an initial 3-year breast cancer treatment course and later successful brain tumor surgery following repeated cancer involvement in multiple organs.

Painful eye metastasis from Stage IV gastric cancer

Patient Info: Anonymized, male | Stage IV

Metastatic Site: bone, choroid of left eye

The eye surgery relieved his pain, but he died 2 months later.

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Stage IV Colorectal Cancer: Gene's Survivor Story

Patient Info: Gene Jones, Male, 50s | Stage IV

Metastatic Site: Liver; lung

As of July 2023, Gene was an 81-year-old, 30-year Stage IV colon cancer survivor with no active colon cancer reported after chemotherapy, cryoablation/liver surgery, later liver surgery, and left-lung surgery.

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Stage IV Colorectal Cancer: Michelle's Patient Story

Patient Info: Michelle Cappel, Female, 40s | Stage IV

Metastatic Site: Leg/femoral nerve area

As of July 2023, Michelle was living with recurrent Stage IV colorectal cancer after prior NED, leg/femoral-nerve recurrence, radiation, surgery with clear margins, and ongoing surveillance.

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Stage IV Stomach Cancer With Recurrent Bowel Obstruction and Severe Pain

Patient Info: Anonymized, Male | Stage IV

Metastatic Site: splenic flexure|perineal nodule

He remained on palliative treatment more than 6 months after the described admission and had 3 additional hospitalizations for recurrent partial small-bowel obstruction, all managed without surgery.

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Stage IV Colorectal Cancer: Michelle's Survivor Story

Patient Info: Michelle Cappel, Female, 40s | Stage IV

Biomarkers: Lynch syndrome negative; no hereditary genetic markers reported

Metastatic Site: Ovary

As of July 2023, Michelle had achieved no evidence of disease after FOLFOX chemotherapy and 12-hour surgery for Stage IV colorectal cancer with ovarian metastasis, while continuing to live with scan anxiety and surveillance.

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MET-mutated lung cancer: testing savolitinib before surgery

Patient Info: Anonymized, Male, 60s | Stage IV

Biomarkers: MET exon 14 skipping, TP53 and BRAF mutations; PD-L1 expression 5%

Metastatic Site: pleura; mediastinal lymph node

Savolitinib produced a partial radiological response, but surgery confirmed persistent pleural and mediastinal nodal metastases with ypStage IVA disease. He recovered and continued adjuvant savolitinib.

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Metastatic breast cancer with a blood condition that mimicked multiple myeloma

Patient Info: Anonymized, Female | Stage IV

Biomarkers: Oestrogen receptor-positive

Metastatic Site: bone

Her pain came under control and the metastatic breast cancer remained stable for approximately 5 years. MGUS did not progress to myeloma, and she later died from causes unrelated to cancer.

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My Stage 4 Colorectal Cancer Story: How I Never Lost Hope

Patient Info: Jason Randall, Male | Stage IV

Metastatic Site: Liver; lungs; bone/sacrum

As of June 2023, Jason had a negative Signatera test, CT scans showing 9 months with no evidence of disease, and about 2.5 years off chemotherapy after Stage IV colorectal cancer treatment and lung ablation.

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Stage IV Colorectal Cancer: Bart's Survivor Story

Patient Info: Bart Wilson, Male, Under 40 | Stage IV

Metastatic Site: Liver

As of May 2023, Bart had shown no evidence of disease for almost 3 years after surgery, FOLFOX, portal vein embolization, extended right hepatectomy, and adjuvant capecitabine for Stage IV colon cancer with liver metastases.

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