Stage IV Triple-Negative Breast Cancer: April's Patient Story

Patient Info: April Donaldson, Female, 40s | Stage IV

Biomarkers: Triple-negative breast cancer; BRCA1 positive

Metastatic Site: Lungs

As of September 2023, April was living with Stage IV metastatic triple-negative breast cancer in the lungs; scans were stable in February but showed growth again in July, and PARP inhibitor therapy was being planned.

The Patient StoryRead more →

Triple-Negative Breast Cancer: Susan's Patient Story

Patient Info: Susan, Female, 70+

Biomarkers: BRCA negative; earlier breast cancer described as triple-negative; later breast cancer estrogen-positive and progesterone-positive; HER2 not reported

As of August 2023, Susan was living after multiple breast cancer diagnoses, including a later estrogen-positive/progesterone-positive non-metastatic breast cancer treated with bilateral mastectomy and ongoing 5-year estrogen-blocker therapy.

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Kelly's Stage 3 Breast Cancer Story: “I’m Still Here & THRIVING!"

Patient Info: Kelly Thomas, Female, Under 40 | Stage III

Biomarkers: Initial triple-negative breast cancer; after surgery

As of August 2023, Kelly was 5 years from her Stage IIIC triple-negative breast cancer diagnosis with no recurrence reported.

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Stage I Triple-Negative Breast Cancer: Melissa's Survivor Story

Patient Info: Melissa Berry, Female, 40s | Stage I

Biomarkers: BRCA mutation reported; triple-negative breast cancer

As of July 2023, Melissa was a 10-year Stage I triple-negative breast cancer survivor with no recurrence reported.

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Melissa’s Stage 1 Triple-Negative Breast Cancer Story

Patient Info: Melissa Berry, Female, 40s | Stage I

Biomarkers: BRCA-positive carrier status; ER-negative; PR-negative; HER2-negative

Melissa described herself as a 10-year triple-negative breast cancer survivor and said she remained without evidence of disease, with annual oncology follow-up.

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BRCA1 Breast Cancer: Carol's Survivor Story

Patient Info: Carol Arnhart

Biomarkers: BRCA1 mutation

She had a complete pathologic response to breast chemotherapy and later reported no evidence of breast cancer.

MD AndersonRead more →

Stage II HR-Positive Lung Cancer: Christine's Survivor Story

Patient Info: Christine, Female | Stage II

Biomarkers: Lung cancer biomarkers not reported; prior breast cancer described as ER-positive, PR-positive, HER2-positive / triple-positive

Reached complete remission from both Stage III triple-positive breast cancer and a separate Stage IIA primary lung cancer after about 1 year, including breast cancer chemotherapy/radiation and lower lung resection.

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Stage IV HR-Positive Breast Cancer: Abigail's Patient Story

Patient Info: Abigail Myers, female, Under 40 | Stage IV

Biomarkers: ER-positive, PR-positive, HER2-positive

Metastatic Site: bones, brain

Abigail continued living with Stage IV metastatic breast cancer after about 8 years of multiple treatment lines, including therapy for bone and brain metastases.

Dana-FarberRead more →

Triple-Negative Bilateral Breast Cancer Treated With Surgery, Radiation, and Oral Chemotherapy

Patient Info: Anonymized, Female | Stage I

Biomarkers: Triple-negative breast cancer; germline BRCA1 pathogenic variant confirmed later

She completed radiotherapy and 2 years of tegafur-uracil without evidence of breast-cancer recurrence.

PubMed CentralRead more →

Triple-Negative Breast Cancer: Lucy's Survivor Story

Patient Info: Lucy E., Female, Under 40

Biomarkers: BRCA1 mutation; triple-negative breast cancer

As of January 2023, Lucy had been told she was all-clear/cancer-free after chemotherapy, had undergone double mastectomy with staged reconstruction planning, and was continuing close oncology reviews every 3-4 months.

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Stage II Triple-Negative Breast Cancer: Lucy's Patient Story

Patient Info: Lucy, Female, Under 40 | Stage II

Biomarkers: BRCA1 mutation; triple-negative breast cancer

As of January 2023, Lucy had gone through fertility preservation, chemotherapy, and double mastectomy for Stage II grade 3 triple-negative breast cancer with BRCA1 mutation; no NED or recurrence status was stated.

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Stage II HR-Positive Breast Cancer: Becki's Patient Story

Patient Info: Becki, Female, 40s | Stage II

Biomarkers: ER-positive; PR-positive; HER2-positive

As of 2023, Becki was receiving ongoing treatment for Stage II triple-positive breast cancer after recently completing mastectomy and experiencing chemotherapy-related fatigue, hair loss, and chemo fog.

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Stage I Triple-Negative Breast Cancer: Emma's Patient Story

Patient Info: Emma, Female, 40s | Stage I

Biomarkers: Left breast: triple-negative; right breast: ER-positive

As of the 2023 story, Emma was receiving chemotherapy for Stage I bilateral breast cancer after the initial multimodality plan was changed because of borderline white blood cells.

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Stage I Triple-Negative Breast Cancer: Tracy's Patient Story

Patient Info: Tracy | Stage I

Biomarkers: Triple-negative

Some time after treatment, Tracy remained worried that her triple-negative breast cancer might not go away.

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Triple-Negative Breast Cancer: Stephanie's Survivor Story

Patient Info: Stephanie, Female, Under 40

Biomarkers: ER-negative; PR-negative; HER2-negative; genetic testing negative

As of October 2022, Stephanie had completed treatment for triple-negative breast cancer in January 2022, follow-up tests showed she was cancer-free, and she had no evidence of cancer.

Cleveland ClinicRead more →

Metastatic Breast Cancer Reclassified After NTRK Fusion Testing

Patient Info: Anonymized, Female | Stage IV

Biomarkers: ETV6-NTRK3 fusion detected in tissue but not circulating tumor DNA; ER low-positive; PR-negative; HER2-negative; PD-L1-negative; germline CHEK2 variant of uncertain significance

Metastatic Site: lungs and pleura; hilar, mediastinal and retrocaval…

After tissue testing identified an ETV6-NTRK3 fusion, treatment with larotrectinib produced a rapid clinical and radiological response.

PubMed CentralRead more →

Triple-Negative Breast Cancer: Kara's Survivor Story

Patient Info: Kara Niewohner, Female, 40s

Biomarkers: BRCA2 mutation; triple-negative

No trace of breast cancer remained after the September 2021 double mastectomy, and no radiation or additional breast-cancer treatment was needed.

Dana-FarberRead more →

Stage IV Triple-Negative Breast Cancer: Julie's Patient Story

Patient Info: Julie Campbell, Female | Stage IV

Biomarkers: triple-negative

Julie died on April 17, 2022.

Triple-Negative Breast Cancer Recurring in Groin Lymph Nodes

Patient Info: Anonymized, Female | Stage IV

Biomarkers: ER-negative; PR-negative; HER2-negative

Metastatic Site: right inguinal lymph node; right iliac/pelvic lymph…

Her condition deteriorated after 3 cycles of palliative capecitabine. She developed vomiting, headache and seizures concerning for brain metastases and died about 4 months after the groin metastasis was detected.

PubMed CentralRead more →

Triple-Negative Breast Cancer: Elizabeth's Patient Story

Patient Info: Elizabeth Cahn

Biomarkers: triple-negative

Elizabeth Cahn chose a clinical trial for triple-negative breast cancer in part to contribute to treatments that could help future patients.

Dana-FarberRead more →

Stage III Triple-Negative Breast Cancer: Marlena's Patient Story

Patient Info: Marlena Murphy, Female, 40s | Stage III

Biomarkers: triple-negative

Later testing found cancer cells after Marlena noticed a small bump under her right arm. She died on July 3, 2024.

Triple-Negative Breast Cancer in Her 30s Led to a Lynch Syndrome Diagnosis

Patient Info: Anonymized, Female

Biomarkers: Triple-negative breast cancer; germline MSH2 c.2458+976A>G likely pathogenic deep intronic splice variant identified by concurrent DNA and RNA testing

A woman diagnosed with triple-negative breast cancer and colon cancer in her mid-30s was found through RNA sequencing to carry a deep intronic MSH2 Lynch syndrome variant.

PubMed CentralRead more →

BRCA Breast Cancer: Christie's Patient Story

Patient Info: Christie Siebel, female, Under 40

Biomarkers: BRCA mutation

At the latest update, Christie was doing well and attending annual breast cancer follow-up visits.

MD AndersonRead more →

Triple-Negative Breast Cancer: Sandra's Survivor Story

Patient Info: Sandra Monsonís, Female, 40s

Biomarkers: Triple-negative breast cancer; BRCA-positive

As of November 2021, Sandra felt healthy and happy after treatment for triple-negative breast cancer, BRCA-positive testing, double mastectomy, implant complication care, external prosthesis, and ovary removal to reduce future cancer risk.