Triple-Negative Breast Cancer: Susan's Patient Story

This breast cancer diagnosis at a glance

Biomarkers
BRCA negative; earlier breast cancer described as triple-negative; later breast cancer estrogen-positive and progesterone-positive; HER2 not reported
Sex
Female
Treatment
surgery, chemotherapy, radiation and hormone therapy
Outcome
Care Ongoing

Treatment course, step by step

  1. Initial left breast cancer in 2000: surgical removal after fine needle aspiration was falsely negative
  2. MD Anderson lumpectomy/additional margin surgery with sentinel node biopsy; 5 lymph nodes negative
  3. IV chemotherapy, 6 treatments given every 3 weeks; regimen name not recalled
  4. 6.5 weeks of radiation
  5. mammograms every 6 months, then annually, with long-term negative follow-up. Later breast cancer in 2021: mammogram and biopsy after nipple change; estrogen-positive and progesterone-positive, not metastatic
  6. bilateral mastectomy with aesthetic flat closure and nipple removal because the tumor was under the nipple
  7. 5-year estrogen blocker.

What happened, in summary

Susan was 72 when she shared a long history with breast cancer. Her first diagnosis began in 2000, when her husband, a physician, felt a small hard lump in her left breast. A fine needle aspiration missed the cancer 3 times, but surgical removal showed the lump was malignant. At MD Anderson, Susan had a lumpectomy with additional margin surgery and sentinel node biopsy. Five lymph nodes were removed and all were negative. Her oncologist recommended chemotherapy and radiation. She received 6 IV chemotherapy treatments 3 weeks apart, though she no longer remembered the regimen name. Anti-nausea medicines caused allergic reactions early on, and one treatment was especially hard when antiemetics were missed. She then completed 6.5 weeks of radiation and continued follow-up mammograms every 6 months, then yearly. The results stayed negative, and 10 years later she celebrated a cancer-free anniversary. In 2015, Susan was diagnosed with Parkinson’s disease. In 2021, a change in the appearance of her nipple led to mammogram and biopsy. This cancer was different: estrogen-positive and progesterone-positive, and not metastatic. Susan chose bilateral mastectomy without reconstruction, with aesthetic flat closure, because the tumor was under the nipple. As of August 2023, she was on a 5-year estrogen blocker and continuing to adjust emotionally to life after surgery.

Where this story comes from

This is a lay summary of an account first published by The Patient Story. Read the original in full

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