Triple-Negative: 166 Real Stories

166 stories match triple-negative. 141 of them mention surgery.

A patient, who was diagnosed with Stage III Breast CancerBreast Cancer

Triple-negative breast cancer: partial response to TAC chemotherapy

Patient Info: Anonymized, Female, 70+ | Stage III

Biomarkers: Triple-negative breast cancer with EGFR positivity and high Ki-67; BRCA1 staining was positive by IHC.

After 1 cycle of TAC chemotherapy, the large ulcerated breast tumor shrank enough for surgery. Radical mastectomy with adjacent flap transfer achieved clear margins and no nodal metastatic cancer; she was recovering at home while awaiting planned postoperative AC-T chemotherapy.

PubMed Central
OutcomeCare Ongoing
A patient, who was diagnosed with Breast CancerBreast Cancer

Triple-Negative Breast Cancer in a Family With a Rare MT1E Variant

Patient Info: Anonymized, female, 50s

Biomarkers: Triple-negative; BRCA1/2 no pathogenic variants; MT1E c. variant identified in this family

A 56-year-old woman with a strong family history of breast cancer was treated surgically for triple-negative breast cancer while genetic testing identified a rare MT1E variant in the family.

PubMed Central
OutcomeNot reported
A patient, who was diagnosed with Stage IV Breast CancerBreast Cancer

Triple-negative breast cancer: partial response to immunotherapy combination

Patient Info: Anonymized, Female, 40s | Stage IV

Biomarkers: Initial tumor: ER-negative; PR-negative; HER2-negative; Ki-67 >80%

Metastatic Site: left lung, neck lymph nodes, mediastinal lymph nodes

Metastatic triple-negative breast cancer had a partial response after 9 months of pembrolizumab plus MK-4830, with reduced tumor burden, decreased lung and mediastinal metastases, and no new metastatic lesions; immunotherapy continued after prednisone controlled a grade 2 lichenoid eruption.

PubMed Central
OutcomeResponding Well
A patient, who was diagnosed with Stage IV Invasive Ductal CarcinomaBreast Cancer

Triple-positive breast cancer: complete response to targeted therapy

Patient Info: Anonymized, Female, 40s | Stage IV

Biomarkers: Triple-positive breast cancer; SBDS variants present; no detected TP53 variant on MyeloSeq.

Metastatic Site: liver

Stage IV triple-positive breast cancer with liver metastasis achieved complete response after paclitaxel, trastuzumab, pertuzumab, and G-CSF support; complete response was maintained for 18 months after treatment initiation while on maintenance HER2-directed and endocrine therapy.

PubMed Central
OutcomeCancer-Free / NED
A patient, who was diagnosed with Stage IV Breast CancerBreast Cancer

Stage IV triple-negative breast cancer in remission: CBD and exercise for neuropathy

Patient Info: Anonymized, Female, 50s | Stage IV

Biomarkers: Triple-negative breast cancer. Blood and immune inflammation measures were tracked during neuropathy care.

Metastatic Site: liver

She was in remission for more than 5 years after Stage IV breast cancer with a solitary liver metastasis, while later managing chemotherapy-induced peripheral neuropathy with CBD and an exercise program that improved symptoms and function.

PubMed Central
OutcomeCancer-Free / NED
A patient, who was diagnosed with Stage II Invasive Ductal CarcinomaBreast Cancer

Stage 2 triple-negative breast cancer: pathologic complete response to chemotherapy

Patient Info: Anonymized, Female, 40s | Stage II

Biomarkers: Triple-negative breast cancer, with pathogenic PALB2 c.1451T>A variant found in blood/buccal/tumor testing.

As of May 2024, more than 1 year after surgery, she was well and free of cancer after neoadjuvant chemotherapy, mastectomy, reconstruction, and preventive adnexectomy.

PubMed Central
OutcomeCancer-Free / NED
A patient, who was diagnosed with Stage II Breast CancerBreast Cancer

Secretory breast cancer: mastectomy and radiotherapy to no evidence of disease

Patient Info: Anonymized, Female, 60s | Stage II

Biomarkers: ER-negative; PR-negative; HER2-negative; Ki-67 50%; tumor-infiltrating lymphocytes 60%

As of May 2024, 6 months after mastectomy and adjuvant radiotherapy for pT2N0M0 triple-negative secretory breast cancer, clinical examination and imaging showed no evidence of relapse.

PubMed Central
OutcomeCancer-Free / NED
A patient, who was diagnosed with Breast CancerBreast Cancer

Triple-negative metaplastic breast cancer with complete pathologic response to chemotherapy

Patient Info: Anonymized, Female, 40s

Biomarkers: ER-negative; PR-negative; HER2-negative; Ki-67 <10%; CK-positive; S100-positive; focal vimentin-positive

At 1-year follow-up, there were no signs of recurrence after doxorubicin/cyclophosphamide chemotherapy and modified radical mastectomy with complete pathologic response.

PubMed Central
OutcomeCancer-Free / NED
Samantha, who was diagnosed with Breast CancerBreast Cancer

Triple-Negative Breast Cancer: Samantha's Survivor Story

Patient Info: Samantha Salway, Female, Under 40

Biomarkers: ER-negative; PR-negative; HER2-negative

As of May 2024, Samantha had delivered a healthy baby, completed chemotherapy, lumpectomy, radiation and additional chemotherapy, had no current evidence of cancer, and remained under close monitoring.

Cleveland Clinic
OutcomeCancer-Free / NED
Allison, who was diagnosed with Stage I Breast CancerBreast Cancer

Stage I HR-Positive Breast Cancer: Allison's Survivor Story

Patient Info: Allison Tierney, Female | Stage I

Biomarkers: ER-positive; PR-positive; HER2-positive

As of May 2024, Allison had recently completed her cancer treatment journey and reported successful hair preservation with cold capping during Taxol chemotherapy.

The Patient Story
OutcomeSurvivorship / Completed Treatment
A patient, who was diagnosed with Stage III Invasive Ductal CarcinomaBreast Cancer

Triple-negative breast cancer and ovarian cancer treated with chemotherapy and PARP inhibitor

Patient Info: Anonymized, Female, 40s | Stage III

Biomarkers: Germline pathogenic BRCA2 c.6468_6469del; breast tumor triple-negative

As of April 2024, 6-week follow-up after breast and nodal radiation was unremarkable, erythema had resolved, and no breast, chest wall, respiratory, or axillary abnormality was found; longer-term control was not reported.

PubMed Central
OutcomeCare Ongoing
A patient, who was diagnosed with Invasive Ductal CarcinomaBreast Cancer

Freezing treatment (cryoablation) used to manage slow-growing triple-negative breast cancer

Patient Info: Anonymized, Female | Stage Metastatic/Advanced

Biomarkers: ER-negative; PR-negative; HER2-negative; androgen receptor-positive in original tumor; Ki-67 5% initially and 10% at recurrence

At 29 months after recurrence diagnosis and 20 months after the first cryoablation, no viable breast tumor was seen at treated sites, axillary nodes were unchanged, pain was absent, and she remained active and independent.

PubMed Central
OutcomeStable
Allison, who was diagnosed with Stage II Invasive Ductal CarcinomaBreast Cancer

Stage II HR-Positive Invasive Ductal Carcinoma: Allison's Patient Story

Patient Info: Allison Tierney, Female | Stage II

Biomarkers: ER-positive; PR-positive; HER2-positive; CHEK2 mutation; BRCA1/2 negative

As of March 2024, Allison had completed Taxol and Herceptin treatment, was on tamoxifen planned for 10 years, and had moved to 6-month oncology follow-up. No metastatic disease or recurrence was reported.

YouTube — The Patient Story
OutcomeCare Ongoing
SI
Breast Cancer

Stage II Triple-Negative Breast Cancer: Chance's Survivor Story

Patient Info: Chance Osborne, Female, Under 40 | Stage II

Biomarkers: ER-negative; PR-negative; HER2-negative; BRCA1 mutation

As of March 2024, Chance Osborne was a young Stage II TNBC survivor with a BRCA1 mutation, sharing her experience with chemotherapy, double mastectomy recovery, and advocacy.

Dear Cancer, I'm Beautiful (LBBC)
OutcomeSurvivorship / Completed Treatment
Dorian, who was diagnosed with Stage II Invasive Ductal CarcinomaBreast Cancer

Stage II HR-Positive Invasive Ductal Carcinoma: Dorian's Survivor Story

Patient Info: Dorian de Salvo, Female | Stage II

Biomarkers: ER-positive; PR-positive; HER2-positive

As of March 2024, Dorian had a complete response to TCHP chemotherapy, clear surgical margins, and no lymph-node involvement after surgery, with radiation completed and additional care still expected for several months.

The Patient Story
OutcomeCancer-Free / NED
TB
Breast Cancer

Triple-Negative Breast Cancer: Katrina's Survivor Story

Patient Info: Katrina M. Johnson, Female

Biomarkers: ER-negative; PR-negative; HER2-negative

As of February 2024, Katrina M. Johnson was a triple-negative breast cancer survivor, three-time breast cancer survivor, and two-time melanoma survivor discussing self-care after diagnosis.

Dear Cancer, I'm Beautiful (LBBC)
OutcomeSurvivorship / Completed Treatment
Chantal, who was diagnosed with Stage II Breast CancerBreast Cancer

Stage II Triple-Negative Breast Cancer: Chantal's Survivor Story

Patient Info: Chantal, Female, Under 40 | Stage II

Biomarkers: Triple-negative breast cancer; BRCA1 mutation

As of December 2023, Chantal reported that she did not currently have cancer, was followed by medical oncology every 3-4 months, and used Signatera testing because tumor markers were not reliable for her.

The Patient Story
OutcomeCancer-Free / NED
A patient, who was diagnosed with Stage I Breast CancerBreast Cancer

Five Years Without Breast Cancer Recurrence Despite a Markedly Elevated CA 15-3

Patient Info: Anonymized, female, 70+ | Stage I

Biomarkers: ER-positive, PR-positive, HER2-positive

Five years after her Stage I breast-cancer diagnosis, breast imaging and systemic evaluation showed no evidence of recurrence. The markedly elevated CA 15-3 was traced to a separate renal tumor and normalized after nephrectomy.

PubMed Central
OutcomeCancer-Free / NED
A patient, who was diagnosed with Stage IV Invasive Lobular CarcinomaBreast Cancer

Treatment-Refractory Triple-Negative Breast Cancer Treated With Tumor-Infiltrating Lymphocytes

Patient Info: Anonymized, female, Under 40 | Stage IV

Biomarkers: Germline BRCA1 pathogenic variant; later triple-negative phenotype

Metastatic Site: skin, lungs, bones

Tumor burden briefly decreased after tumor-infiltrating lymphocyte therapy, but she developed severe treatment complications followed by rapid cancer relapse and died about 1 month after the TIL/IL-2 treatment began.

PubMed Central
OutcomeIn Memory
A patient, who was diagnosed with Stage IV Breast CancerBreast Cancer

Adenoid Cystic Breast Cancer Spreads to the Kidney, Lungs, Bone and Spleen

Patient Info: Anonymized, female, 70+ | Stage IV

Biomarkers: Triple-negative

Metastatic Site: kidneys, lungs, spleen, bone, lymph nodes

The cancer progressed from an initial kidney metastasis to widespread disease involving the lungs, spleen, right kidney, lymph nodes, and C4 vertebra. By May 2022 she had worsening cachexia and pain, and best supportive care was recommended.

PubMed Central
OutcomeSetback / Progression