Targeted Therapy: 297 Real Stories

297 stories match targeted therapy. 183 of them mention chemotherapy.

  1. Stage IV ALK Lung Cancer: Jake’s Patient Story

    Stage 4 · ALK Positive · Chemotherapy · Clinical Trial

    Jake was 15 when severe migraines began in late 2012. For about 25 days, he hid the pain, took large amounts of Advil, and kept playing sports until his mother pushed for an MRI. The scan showed a golf-ball-sized tumor in his cerebellum. After brain surgery…

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  2. Stage IV BRCA Breast Cancer: Maralee’s Survivor Story

    Stage 4 · BRCA Mutation · Chemotherapy · Fertility Preservation

    Maralee Lellio was 28 when she noticed a breast lump in 2018. A first evaluation called it a benign fibroadenoma, but the lump grew and became painful. Further mammogram and biopsy showed Stage II breast cancer. Before treatment, Maralee and her husband froze…

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  3. Stage IV ALK Lung Cancer: Kartik’s Patient Story

    Stage 4 · ALK Positive · Clinical Trial · Targeted Therapy

    Kartik was 28 and a third-year internal medicine resident when he was diagnosed with Stage IV lung cancer. Molecular testing identified an EML4/ALK mutation, and he entered a targeted clinical trial. That treatment allowed him to continue working in medicine…

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  4. Stage IV Colorectal Cancer: Helen’s Survivor Story

    Stage 4 · Chemotherapy · FOLFIRI

    Helen was 49 when symptoms that seemed like a urinary tract infection led to a Stage IV sigmoid colon cancer diagnosis. She had pelvic pressure, burning with urination, bowel changes, bloating, and low energy. After 3 rounds of antibiotics and 2 enemas that…

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  5. Stage II Lung Cancer: Michelle’s Patient Story

    Stage 2 · Chemotherapy · Fertility Preservation

    Michelle’s lung cancer was found while doctors were investigating a completely different problem. After a fall, she developed persistent pain that moved into her jaw, head, and neck and caused migraine-like symptoms. Months of physical therapy, pain…

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  6. Stage IV Breast Cancer: Erica’s Patient Story

    Stage 4 · Hormone Receptor Positive · Chemotherapy · Hormone Therapy

    Erica was 41, active, and working as a P.E. teacher when breast cancer became part of her daily life again. Her first diagnosis was Stage I hormone-positive, HER2-negative breast cancer. She completed chemotherapy in February 2025 and had a double mastectomy…

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  7. Stage IV EGFR Lung Cancer: Kelsey’s Patient Story

    Stage 4 · ALK Positive · Chemotherapy · Clinical Trial

    Kelsey was 36, a mother of 4, and working as a SoulCycle manager when severe back pain began changing her life. At first, she blamed work, commuting, aging, or a pulled muscle. Then she collapsed while coaching baseball and later had to crawl to the bathroom…

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  8. Stage II EGFR Non-Small Cell Lung Cancer: Daniel’s Patient Story

    Stage 2 · EGFR Mutation · Chemotherapy · lobectomy

    Daniel West had no symptoms before a routine heart scan in October 2022 showed 2 nodules in his right lung. A bronchoscopy biopsy confirmed early-stage non-small cell lung cancer. Daniel, who had quit smoking in 2006, sought a second opinion at UT MD Anderson…

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  9. Stage IV Colorectal Cancer: Jim’s Patient Story

    Stage 4 · bevacizumab · Chemotherapy

    Jim was 43 and felt healthy when routine blood work changed everything. A physical for an insurance discount showed high liver enzymes, and repeat blood work stayed abnormal. An ultrasound found multiple liver masses, followed by a biopsy and CT scan. He was…

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  10. Stage IV ALK Non-Small Cell Lung Cancer: Megan’s Survivor Story

    Stage 4 · ALK Positive · Targeted Therapy

    Megan was 33, active, a never-smoker, and raising 2 young children when chest pain began. Urgent care and ER visits first led to explanations such as a pulled muscle or anxiety. Then she developed shortness of breath on walks, arm pain, and visible veins in…

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  11. Stage IV Colorectal Cancer: Joe’s Patient Story

    Stage 4 · capecitabine · Chemotherapy

    Joe never had blood in his stool. His warning signs were fatigue, loss of appetite, feeling generally off, and then severe shoulder, back, stomach, and liver-area pain. Because he worked long hours in the restaurant industry, the fatigue was easy to explain…

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  12. Stage IV Colorectal Cancer: Alyssa’s Patient Story

    Stage 4 · Chemotherapy · FOLFIRI

    Alyssa Kelly was 38 and pregnant in early 2021 when abdominal discomfort, weight loss and a concerning ultrasound finding led to an MRI. The news came by phone: Stage IV colon cancer. The main tumor was the size of a softball and pressed on her uterus…

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  13. Stage III EGFR Lung Cancer: Roxanne’s Patient Story

    Stage 3 · EGFR Mutation · Chemotherapy · lobectomy

    Roxanne was 43, a single mother, and a special needs teacher when lung cancer was found almost by accident. She had gone to her gynecologist for abdominal pain that felt like an ovarian cyst. A CT scan did show a cyst, but it also caught part of her right…

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  14. Stage IV HER2-Positive Breast Cancer: Christina’s Patient Story

    Stage 4 · HER2 Positive · Chemotherapy · Radiation

    Christina spent months feeling that something was wrong. In January 2024, she felt as if she had a cold, with swelling around her neck and head. The problem worsened, and she repeatedly told her doctor she felt seriously ill. She later learned that the…

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  15. Stage IV EGFR Non-Small Cell Lung Cancer: Maggie’s Patient Story

    Stage 4 · EGFR Mutation · Chemotherapy · Clinical Trial

    Maggie was 60 in 2021 and expected the year to be one of the best of her life. Instead, unusual symptoms led to a Stage IV lung cancer diagnosis. She first had an ocular migraine, then leg pain that turned out to be a partial blood clot. A CT scan showed…

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  16. Stage IV ALK Non-Small Cell Lung Cancer: Clara’s Patient Story

    Stage 4 · ALK Positive · Biomarker Testing · Chemotherapy

    Clara was living with Stage IV lung cancer when a difficult stretch of treatment nearly made her stop. She had already completed 7 rounds of chemotherapy and 10 rounds of radiation. During the summer, she also received immunotherapy, and August scans brought…

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  17. Triple-Negative Breast Cancer: Jacqueline’s Patient Story

    HER2 Positive · Chemotherapy · lumpectomy

    Jacqueline Bennett first noticed a breast lump months before diagnosis, but several doctors dismissed it as mastitis. In June 2017, shortly after learning she was pregnant again, a new OB/GYN sent her for ultrasound and biopsy. The biopsy confirmed breast…

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  18. Stage IV ROS1 Lung Cancer: Phil’s Patient Story

    Stage 4 · ROS1 Positive · Chemotherapy · Clinical Trial

    Phil was an active 60-year-old looking toward retirement when a cough would not go away. At first, doctors treated it like a sinus infection or pneumonia. A CT scan was read as not cancer, and the start of COVID delayed further evaluation. After an 8-month…

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  19. Stage IV ALK Non-Small Cell Lung Cancer: Stephanie’s Patient Story

    Stage 4 · ALK Positive · Chemotherapy · Targeted Therapy

    Stephanie was diagnosed with Stage IV non-small cell lung cancer in December 2024, shortly after turning 44. She had been healthy, working full time, raising 2 teenage daughters, and recovering from COVID when a hacking cough returned. She treated it like a…

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  20. Stage II HR-Positive Invasive Ductal Carcinoma: Janet’s Patient Story

    Stage 2 · ATM Mutation · Chemotherapy · Fertility Preservation

    Janet Ayala was 35 when she felt a breast lump while getting ready for a shower in summer 2024. After difficulty getting a diagnostic mammogram appointment, she finally had imaging in September and was told right away it was breast cancer. The diagnosis was…

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  21. Stage IV ALK Lung Cancer: Ruchira’s Survivor Story

    Stage 4 · ALK Positive · lobectomy · lorlatinib

    Ruchira had little reason to suspect lung cancer. She was young, healthy, a nonsmoker, and her cough was mild and intermittent. Her father first noticed it, but she ignored it for nearly a year. After she tested positive for COVID, a chest X-ray led to a CT…

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  22. Stage IV Lung Cancer: Tina’s Patient Story

    Stage 4 · Clinical Trial · Surveillance

    Tina Powell shared her experience as a Stage IV lung cancer patient on her 3-year cancerversary. The story focuses on scan anxiety, but it also gives key details about her current care. As of January 2026, she was being treated on a clinical trial at Memorial…

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  23. Stage IV HER2-Positive Colorectal Cancer: John’s Patient Story

    Stage 4 · HER2 Positive · Targeted Therapy

    John E. was 44 when he was given a two-year prognosis and told chemotherapy was his only treatment option. With a wife and two daughters, he wanted another perspective and sought care at Mayo Clinic. Biomarker testing was raised immediately as part of that…

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  24. Stage IV HER2-Positive Breast Cancer: Sonja’s Patient Story

    Stage 4 · HER2 Positive · anastrozole · carboplatin

    Sonja Rideout was diagnosed on October 19, 2022, with Stage II HER2-positive breast cancer after ultrasound and biopsy of a 2-inch breast mass. Her treatment began with 4 months of chemotherapy, followed by a total mastectomy and DIEP flap reconstruction…

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