Targeted Therapy: 297 Real Stories

297 stories match targeted therapy. 183 of them mention chemotherapy.

  1. Stage IV Breast Cancer: Maria’s Patient Story

    Stage 4 · Chemotherapy · Hormone Therapy

    Maria first went through chemotherapy, surgery, radiation, and targeted/endocrine therapy for breast cancer. Surgery showed more lymph-node involvement than expected on PET imaging, and up to 20 lymph nodes were removed. Pathology later showed more cancer in…

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  2. Stage IV ALK Non-Small Cell Lung Cancer: Steven’s Patient Story

    Stage 4 · ALK Positive · Fertility Preservation · Surveillance

    Steven Huff was 29, newly engaged, and starting a teaching career when shortness of breath, a daily cough, and a lump near his collarbone led to a lung cancer diagnosis. Doctors told him he had Stage IV non-small cell lung adenocarcinoma, with cancer in both…

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  3. Stage IV ALK Lung Adenocarcinoma: Allison’s Patient Story

    Stage 4 · ALK Positive · Bone Modifying Agent · Radiation

    Allison was an active 45-year-old mother of 2 when back pain that seemed muscular turned into a much larger warning sign. A CT report mentioned possible metastatic lesions in her spine. More testing followed, including chest imaging, MRI, brain imaging, PET…

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  4. Breast Cancer: Marissa’s Survivor Story

    Bone Modifying Agent · Chemotherapy

    Marissa Coreno was 27 when she felt a breast lump in June 2021. She was young, healthy, living independently, and had no family history of breast cancer, so she did not expect the lump to be serious. Diagnostic imaging at Cleveland Clinic Fairview Hospital…

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  5. Stage IV Breast Cancer: Linda’s Patient Story

    Stage 4 · abemaciclib · anastrozole

    Linda Norman was approaching her 60th birthday in January 2019 when a routine mammogram found a small mass in her left breast. Biopsy confirmed breast cancer. She had a lumpectomy, then 10 radiation treatments over 2 weeks. Anastrozole caused extreme joint…

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  6. Stage IV Breast Cancer: Suzy’s Survivor Story

    Stage 4 · Surgery · Targeted Therapy

    Suzy was a respiratory therapist with 17 years of experience when her own symptoms were dismissed. In late 2022, she noticed a lump under her collarbone and frequent pain in her left breast. A clear mammogram the year before made clinicians less concerned…

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  7. Stage IV HER2-Positive Breast Cancer: Elissa’s Patient Story

    Stage 4 · HER2 Positive · carboplatin · Chemotherapy

    Elissa was 34 and only a few months postpartum when numbness in her feet began interfering with daily life. She could not keep shoes on comfortably and could barely play tennis for 20 to 30 minutes. Because she had recently given birth, the symptoms were easy…

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  8. Stage IV ALK Lung Cancer: Kathrin’s Patient Story

    Stage 4 · ALK Positive · Radiation · Targeted Therapy

    Kathrin was a fitness professional living in Munich when fatigue and foot pain began to interrupt an active life. At first, the foot pain seemed like a sports injury from yoga or exercise. Imaging of the left foot showed a tumor, and biopsy revealed that it…

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  9. Stage II EGFR Lung Cancer: Samantha’s Patient Story

    Stage 2 · EGFR Mutation · Clinical Trial · osimertinib

    Samantha Vaughn first noticed breathlessness and hoarseness after having COVID in 2022. For about 6 months, the symptoms were treated as long COVID, sinus problems, or infection, with inhalers, steroids, and antibiotics that did not help. In May 2023, she…

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  10. Stage IV HER2-Positive Breast Cancer: Kathleen’s Patient Story

    Stage 4 · HER2 Positive · Chemotherapy · Clinical Trial

    Kathleen McEvoy-Schufreider was first diagnosed in 2011 with early-stage HER2-positive, hormone receptor-positive breast cancer. She joined a clinical trial and received 16 weeks of paclitaxel with trastuzumab. After surgery, she received 4 doses of AC…

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  11. Stage IV HER2-Positive Breast Cancer: Jennifer’s Survivor Story

    Stage 4 · HER2 Positive · Chemotherapy · Clinical Trial

    Jennifer Masters was 63 when she described the long road through Stage IV HER2-positive metastatic breast cancer. She first noticed a lump in her left breast in February 2016 but waited several months before seeing a doctor. After a diagnosis of HER2-positive…

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  12. Stage IV ALK Non-Small Cell Lung Cancer: Alisa’s Patient Story

    Stage 4 · ALK Positive · alectinib · carboplatin

    Alisa Secaida was 35 when cough, fatigue, shortness of breath, chest tightness and shoulder pain were dismissed as asthma or long COVID. She paid for her own CT scan, which showed a mass in the upper left lung, and later biopsy confirmed Stage IVB non-small…

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  13. Stage IV EGFR Lung Cancer: Natasha’s Patient Story

    Stage 4 · EGFR Mutation · osimertinib · Radiation

    Natasha, a primary school teacher from Yorkshire, England, was diagnosed with EGFR-positive lung cancer in January 2023 after months of cough, hoarse voice, and squeaky breathing. She was active and had never expected lung cancer, especially as a nonsmoker…

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  14. Stage IV HR-Positive Invasive Ductal Carcinoma: Samantha’s Patient Story

    Stage 4 · ER Positive · abemaciclib · anastrozole

    Samantha was 22 when a breast lump, initially treated as an infection, was confirmed as cancer. Further imaging found a small rib lesion that shrank with chemotherapy, showing that the disease had already spread and making the diagnosis stage 4. She received…

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  15. Stage II HR-Positive Breast Cancer: Kelsey’s Patient Story

    Stage 2 · ER Positive · abemaciclib · AC-T

    Kelsey was 27 when she felt a slightly tender breast lump in May 2023. Her primary care doctor initially thought it might be a cyst, but ultrasound and mammogram showed something more serious: Stage IIB estrogen-positive breast cancer. The diagnosis was…

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  16. Stage IV EGFR Lung Cancer: Leah’s Patient Story

    Stage 4 · EGFR Mutation · lobectomy · osimertinib

    Leah Phillips, co-founder of the Young Lung Cancer Initiative, was diagnosed in December 2019 with Stage IV lung cancer carrying an EGFR exon 19 deletion. At diagnosis, her primary tumor was in the right middle lobe of the lung, and she had 13 bone metastases…

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  17. Stage IV HER2-Positive Breast Cancer: Stephani’s Survivor Story

    Stage 4 · capecitabine · Chemotherapy

    Stephani St. Cyr felt a long lump under her right arm while watching a movie at home. Her primary doctor suspected a cyst but referred her to a specialist. The breast cancer doctor immediately suspected cancer, and biopsy confirmed it. Further tests showed…

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  18. Stage IV ROS1 Lung Adenocarcinoma: Luna’s Patient Story

    Stage 4 · ROS1 Positive · Antiangiogenic Therapy · bevacizumab

    Luna Okada was 54 when she was diagnosed in December 2012 with Stage IV lung adenocarcinoma. She had just returned from climbing Machu Picchu and had no cough or shortness of breath. Two days after the trip, severe abdominal pain brought her to the emergency…

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  19. Stage IV HER2-Positive Breast Cancer: Anne’s Patient Story

    Stage 4 · HER2 Positive · Chemotherapy · pertuzumab

    Anne Keane was diagnosed in 2016 after pain in her sternum led to testing that found HER2-positive breast cancer already involving her bones and liver. She was a young mother, and learning that the disease was metastatic and incurable was devastating. At 42…

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  20. Stage IV KRAS Lung Cancer: Rosemary’s Patient Story

    Stage 4 · KRAS Mutation · Chemotherapy · Clinical Trial

    Rosemary Conway was 60 when she was diagnosed with lung cancer in August 2017 after developing a raspy voice and coughing up a small amount of blood. She had never smoked and was an active runner. In September, surgeons removed the lower lobe of her left lung…

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  21. Stage IV EGFR Non-Small Cell Lung Cancer: Jeff’s Patient Story

    Stage 4 · EGFR Mutation · osimertinib · Targeted Therapy

    Jeff had already survived an unusual cancer experience before his lung cancer diagnosis. In 2017, a painful cervical spine mass was first treated as a likely non-cancerous schwannoma, but surgery showed cancer and could not remove everything safely because of…

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  22. Stage IV Colorectal Cancer: Jennifer’s Survivor Story

    Stage 4 · Single Nthl1 Mutation · cetuximab · Chemotherapy

    Jennifer Trefzger was diagnosed with colon cancer at 23 in 2017 after years of symptoms and severe iron deficiency. A colonoscopy found a 5 cm tumor blocking her descending colon. She was initially told the cancer was Stage III, but later learned it had…

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  23. Stage III HR-Positive Invasive Lobular Carcinoma: Katie’s Patient Story

    Stage 3 · ER Positive · abemaciclib · AC-T

    Katie, a nurse in Cleveland, was 38 when she was diagnosed with Stage III invasive lobular carcinoma in March 2024. She had been referred to a high-risk breast clinic because her mother and 2 sisters had developed breast cancer, but her first mammogram and…

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  24. Stage IV ALK Lung Cancer: Sydney’s Patient Story

    Stage 4 · ALK Positive · Targeted Therapy

    Sydney Barned was 33 and completing her internal medicine residency when she was diagnosed with Stage IV ALK-positive lung cancer in 2017. She had always been active, including ballet, track, swimming, and 5K runs, so the first sign was subtle but…

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