Stage I Transverse Colon Cancer Among Five Synchronous Gastrointestinal Cancers

Patient Info: Anonymized, male, 50s | Stage I

Six years after the operation, he remained without recurrence or metastasis and continued regular follow-up.

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Stage III Rectal Cancer Among Five Synchronous Gastrointestinal Cancers

Patient Info: Anonymized, male, 50s | Stage III

Six years after surgery and adjuvant treatment, he remained without recurrence or metastasis and continued regular follow-up.

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Stage I Gastric Cancer Among Five Synchronous Gastrointestinal Cancers

Patient Info: Anonymized, male, 50s | Stage I

Six years after the operation, he remained without recurrence or metastasis and continued regular follow-up.

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Stage IV HER2-Positive Breast Cancer: Sarah's Patient Story

Patient Info: Sarah, Female, Under 40 | Stage IV

Biomarkers: HER2-positive; BRCA and other known hereditary breast cancer genes not identified in family history discussion

As of January 2017, Sarah had been living for almost 3 years with recurrent Stage IV HER2-positive breast cancer and was receiving Kadcyla every 3 weeks.

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Colorectal Cancer: Theresa's Survivor Story

Patient Info: Theresa Cotton, Female, 40s

As of January 2017, Theresa was cancer-free for more than 5 years after colorectal cancer treatment that included complete hysterectomy, permanent colostomy, chemotherapy and 28 radiation treatments.

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Stage II Breast Cancer: Tasha's Patient Story

Patient Info: Tasha | Stage II

She completed surgery and radiation and is doing well as a survivor while continuing tamoxifen.

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Stage III Breast Cancer: Elizabeth's Survivor Story

Patient Info: Elizabeth, 40s | Stage III

Biomarkers: Cancer described as highly hormone-dependent.

Elizabeth said she was in remission and no longer required treatment after lumpectomy, chemotherapy, radiation, and an aromatase-inhibitor clinical trial.

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Stage III Colorectal Adenocarcinoma: Anne's Survivor Story

Patient Info: Anne, Under 40 | Stage III

Anne was declared cancer-free in December 2017 and reports doing well 7 years after treatment.

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Lung Cancer Immunotherapy Caused New Type 1 Diabetes

Patient Info: Anonymized, Male, 70+ | Stage IV

Biomarkers: No ALK, ROS1, KRAS or EGFR alteration was detected; CK7-positive; TTF-1-negative; PAX-negative; CK20-negative

Metastatic Site: Pleura

After 4 combination-treatment cycles, the right-lung nodules had decreased markedly and nearly resolved. He continued maintenance pembrolizumab every 3 weeks and remained on insulin with stable glucose control.

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Stage IV Breast Cancer: Debora's Patient Story

Patient Info: Debora, Female, 60s | Stage IV

Debora was living with metastatic breast cancer after Stage III disease treated with surgery, chemotherapy, radiation therapy, and targeted therapy; four years after surgery, she was told the cancer had metastasized and was on targeted therapy.

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Gastric Cancer: Amanda's Survivor Story

Patient Info: Amanda

Biomarkers: CDH1 gene deletion

About 7 years after gastrectomy and mastectomy, Amanda said all of the cancer had been removed, although long-term effects of surgery continued to affect daily life.

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Pulmonary Carcinoid Tumorlets Found After Lung Surgery for Chronic Cough and Bronchiectasis

Patient Info: Anonymized, male, 60s

His cough improved after lobectomy, an octreotide scan was normal, and he continued close follow-up with no evidence of distant metastasis or carcinoid syndrome.

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Breast Cancer: Amanda's Survivor Story

Patient Info: Amanda

Biomarkers: CDH1 gene deletion

About 7 years after gastrectomy and mastectomy, Amanda said all of the cancer had been removed, although long-term effects of surgery continued to affect daily life.

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Stage II Breast Cancer: Natalia's Survivor Story

Patient Info: Natalia | Stage II

Natalia was declared cancer-free on February 21, 2024, and continued regular follow-up while taking letrozole.

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BRCA1 Non-Small Cell Lung Cancer: Nadine's Survivor Story

Patient Info: Nadine Beech, Female, Under 40

Biomarkers: Germline BRCA1 mutation for hereditary breast/ovarian cancer risk; lung cancer biomarker not reported

As of November 2016, Nadine was cancer-free after right bilobectomy for recurrent non-small cell lung cancer, following 19 years of lung cancer management that included left lower lobectomy, surveillance, Tarceva, and risk-reducing surgery for germline BRCA1.

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Male Breast Cancer Treatment Complicated by Stevens-Johnson Syndrome

Patient Info: Anonymized, male, 60s

After the third chemotherapy cycle he developed severe Stevens-Johnson syndrome with disseminated intravascular coagulation and multiorgan failure, and he died after care was shifted to comfort measures.

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Stage III HER2-Positive Invasive Ductal Carcinoma: Dorothy's Survivor Story

Patient Info: Dorothy Paterson, Female, 40s | Stage III

Biomarkers: HER2-positive

As of November 2016, Dorothy had remained cancer-free since completing treatment for Stage III HER2-positive invasive ductal carcinoma in April 1999.

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A small gastric adenocarcinoma arising in a sporadic fundic gland polyp is removed endoscopically

Patient Info: Anonymized, Male, 60s

A 68-year-old man had a 4-mm gastric adenocarcinoma arising in a sporadic fundic gland polyp removed by endoscopic submucosal dissection.

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A tiny gastric adenocarcinoma arising in a sporadic fundic gland polyp is treated by endoscopic resection

Patient Info: Anonymized, Female, 60s

A 63-year-old woman had a 3-mm gastric adenocarcinoma arising in a sporadic fundic gland polyp removed by endoscopic submucosal dissection.

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Stage IV Lung Cancer: Bill's Patient Story

Patient Info: Bill Smith, Male | Stage IV

Biomarkers: Genomic testing performed; specific result not reported

Metastatic Site: Brain; liver; bone/humerus

As of October 2016, Bill was receiving immunotherapy every 2 weeks, all tumors had shrunk, chemotherapy had stopped and he reported markedly improved quality of life while living with Stage IV lung cancer.

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The Stomach-less Sisters — Case 1

Patient Info: Anonymized, Female | Stage I

Biomarkers: CDH1 mutation

After surgery, she adapted to weight loss and changed eating habits while focusing on family life and hereditary-cancer advocacy.

The Stomach-less Sisters

Patient Info: Anonymized, Female | Stage I

Biomarkers: CDH1 mutation

After surgery, she adapted to weight loss and changed eating habits while raising her family and supporting hereditary-cancer awareness.

Stage III Inflammatory Breast Cancer Diagnosed After Severe Breast Pain and Swelling Following Mammography

Patient Info: Anonymized, female, 60s | Stage IV

Biomarkers: ER negative, PR negative, HER2 highly positive

After later metastatic disease was found, she chose no further active treatment and died of progressive disease in 2012.

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HER2-Positive Right Breast Cancer With Complete Response Before Bilateral Mastectomy

Patient Info: Anonymized, female, 50s

Biomarkers: ER negative, PR negative, HER2 positive

After neoadjuvant treatment, imaging showed complete resolution of the right-breast mass and mastectomy pathology found no residual right-breast tumor or malignant right sentinel node.

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