Breast cancer spreading to the colon, rectum and peritoneal surfaces

Patient Info: Anonymized, Female, 60s | Stage IV

Biomarkers: Primary tumor: ER >80% positive; PR 50–60% positive; HER2 negative; E-cadherin positive. Later colorectal metastases: ER positive; PR negative; HER2 negative; CK7 positive; CK20 negative; CDX2 negative.

Metastatic Site: colon, rectum, peritoneum, diaphragm, liver, bowel,…

Metastatic breast cancer was subsequently confirmed in the colon and rectum, with later laparoscopic biopsies showing peritoneal and additional intra-abdominal metastatic disease.

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Breast cancer recurrence presenting with numb chin syndrome

Patient Info: Anonymized, Female, 50s | Stage IV

Metastatic Site: sternum, left mandibular foramen

She was discharged ambulatory without lower-limb pain, although left mandibular numbness persisted, with monthly oncology follow-up planned.

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Severe patent blue dye allergy during planned breast cancer surgery

Patient Info: Anonymized, Female, 50s

The repeat operation proceeded without blue dyes and without another perioperative allergic reaction.

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Locally advanced transverse colon cancer complicated by a colocutaneous fistula

Patient Info: Anonymized, Female, 60s | Stage III

After initially recovering from surgery, she developed a respiratory infection, sepsis and metabolic encephalopathy and died after cardiorespiratory arrest on postoperative day 12.

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Luminal A breast cancer growing over 1 year in a 76-year-old woman

Patient Info: Anonymized, Female, 70+ | Stage II

Biomarkers: ER positive; PR negative; HER2 negative; Ki-67 20%

She had recovered from surgery and completed radiotherapy about 4 months after the initial operation, with adjuvant hormonal therapy planned.

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Metastatic lung cancer causing recurrent small-bowel intussusception

Patient Info: Anonymized, Female, 50s | Stage IV

Biomarkers: EGFR mutation; exon 19 deletion in metastatic bowel lesions

Metastatic Site: small bowel

She recovered satisfactorily after bowel surgery, and care shifted to palliation with long-term nutritional support planned.

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Colorectal cancer discovered during treatment for Klebsiella endophthalmitis

Patient Info: Anonymized, Male, 60s | Stage II

Post-treatment pathology showed Stage II rectal adenocarcinoma, with a synchronous sigmoid adenocarcinoma also identified.

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Employees' own cancer treatment shapes how they give back

Patient Info: Jamie Bernard, female, Under 40 | Stage II

After mastectomy and chemotherapy, Jamie became active in patient and caregiver support programs at MD Anderson.

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Stage IV Ovarian Cancer: Janelle's Patient Story

Patient Info: Janelle Kister, female | Stage IV

Treatment ended, and Janelle was still doing well 17 years after her Stage IV ovarian cancer diagnosis.

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Colon cancer chemotherapy complicated by a severe manic episode

Patient Info: Anonymized, Male, 40s | Stage III

He completed chemotherapy without further affective episodes on the revised regimen and remained under regular follow-up.

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Stage III Colorectal Cancer: Annie's Patient Story

Patient Info: Annie Schreiber, Female, Under 40 | Stage III

As of March 2018, Annie had recovered from TaTME surgery with a temporary ileostomy instead of a permanent colostomy and was undergoing chemotherapy with a very good prognosis.

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Stage IV gastric cancer with peritoneal metastases responds to combined chemotherapy, surgery and HIPEC

Patient Info: Anonymized, Female, Under 40 | Stage IV

Metastatic Site: peritoneum

At last follow-up in January 2018, she was asymptomatic and examinations showed no evidence of disease.

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Stage IV signet-ring gastric cancer with peritoneal metastases treated with chemotherapy, surgery and HIPEC

Patient Info: Anonymized, Female, 50s | Stage IV

Metastatic Site: peritoneum

Developed peritoneal recurrence 3 months after postoperative chemotherapy and was receiving second-line chemotherapy at follow-up.

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Stage IV signet-ring gastric cancer with peritoneal metastases treated with chemotherapy, gastrectomy and HIPEC

Patient Info: Anonymized, Male, 50s | Stage IV

Metastatic Site: peritoneum

At follow-up, he had no signs of recurrence.

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Stage II metaplastic breast cancer in a 47-year-old man

Patient Info: Anonymized, Male, 40s | Stage II

Biomarkers: ER 1%; PR negative; HER2 negative; E-cadherin positive; p63 positive; genetic testing reported no abnormal mutations

Two years after surgery he was doing well, with only occasional pain at the mastectomy site and a negative recent mammogram of the left breast.

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Breast Cancer: Heather's Survivor Story

Patient Info: Heather Kokinda, Female, Under 40

As of March 2018, Heather had completed chemotherapy and double mastectomy, had a clear scan before trying to conceive again, and had given birth to another daughter in July 2017.

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Robotic gastric cancer surgery in a man with situs inversus totalis and no recurrence at 2.5 years

Patient Info: Anonymized, Male, 50s

Biomarkers: HER2 2+

At 2.5 years after surgery, there was no recurrence.

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Rectal cancer treatment followed by a rare rectovaginal fistula

Patient Info: Anonymized, Female, 60s

After fistula repair and later ileostomy closure, she remained fully continent despite 5–10 liquid bowel movements per day.

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Breast reconstruction after implant loss in a woman with BMI 50.8

Patient Info: Anonymized, Female, 50s | Stage I

At 3-month follow-up, the DIEP flap remained viable with no fat or skin necrosis and a satisfactory aesthetic result.

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Stage IV ovarian cancer presenting as a persistent umbilical ulcer

Patient Info: Anonymized, Female, 40s | Stage IV

Metastatic Site: bilateral cardiophrenic lymph nodes

She recovered from extensive cytoreductive surgery without major abdominal or pulmonary complications and began adjuvant paclitaxel and carboplatin on postoperative day 25.

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Stage III BRCA2 Breast Cancer: Ashley's Survivor Story

Patient Info: Ashley, female, Under 40 | Stage III

Biomarkers: BRCA2 positive; HER2 positive

Ashley described herself as cancer-free after chemotherapy, double mastectomy and 30 rounds of radiation, with 10 months of Herceptin planned.

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Breast Cancer: Michael's Patient Story

Patient Info: Michael Johnston, male

After completing surgery, chemotherapy, and radiation, Michael focused on male breast cancer awareness and on traveling with his wife.

Dana-FarberRead more →

Triple receptor-positive neuroendocrine breast cancer in a 32-year-old woman

Patient Info: Anonymized, Female, Under 40 | Stage III

Biomarkers: ER positive; PR positive; HER2 positive; neuron-specific enolase positive; synaptophysin positive

She was stable on follow-up and was receiving adjuvant chest-wall radiation plus systemic chemotherapy and trastuzumab-based therapy.

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Stage IV Ovarian Cancer With 20 Years of Tumor-Free Survival

Patient Info: Anonymized, female, 50s | Stage IV

Biomarkers: BRCA1 negative, BRCA2 negative

Metastatic Site: peritoneum, liver, right adrenal gland

Regular follow-up found no recurrence or other tumor, and at 20 years of follow-up she remained tumor-free with good health and quality of life.

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