EBV-positive early gastric cancer treated by endoscopic removal in a 61-year-old man

Patient Info: Anonymized, male, 60s

Biomarkers: EBV-positive

Follow-up endoscopy 6 months after treatment showed only a scar at the resection site and no signs of recurrence.

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Stage IIB Gastric Cancer With a Gastric-Wall Abscess

Patient Info: Anonymized, Female, 70+ | Stage II

Biomarkers: Synaptophysin positive; CD56 negative; chromogranin A negative; SALL4 negative

The tumor and abscess were removed completely, and no lymph-node metastases were found. She remained disease-free through 22 months of follow-up.

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EBV-positive early gastric cancer treated by endoscopic removal in a 40-year-old man

Patient Info: Anonymized, male, 40s

Biomarkers: EBV-positive

Follow-up gastroscopy 3 months after endoscopic treatment showed no evidence of recurrence.

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EBV-positive early gastric cancer treated by endoscopic removal in a 69-year-old man

Patient Info: Anonymized, male, 60s

Biomarkers: EBV-positive

Follow-up gastroscopy 12 months after endoscopic treatment showed no signs of recurrence.

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Stage IV gastric cancer with liver metastases cleared after chemotherapy, nivolumab and surgery

Patient Info: Anonymized, male, 60s | Stage IV

Biomarkers: PD-L1-positive, HER2-negative

Metastatic Site: liver

After treatment cleared the gastric and liver lesions, all anticancer therapy was stopped. He remained relapse-free with no evidence of disease for 32 months.

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Triple-Negative Breast Cancer Recurring in Groin Lymph Nodes

Patient Info: Anonymized, Female | Stage IV

Biomarkers: ER-negative; PR-negative; HER2-negative

Metastatic Site: right inguinal lymph node; right iliac/pelvic lymph…

Her condition deteriorated after 3 cycles of palliative capecitabine. She developed vomiting, headache and seizures concerning for brain metastases and died about 4 months after the groin metastasis was detected.

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Stage III Breast Cancer: Christal's Survivor Story

Patient Info: Christal Love, Female, Under 40 | Stage III

Biomarkers: hormone-positive; HER2-negative

After chemotherapy complications, surgery, radiation, later preventive removal of the other breast and reconstruction, Christal remained cancer-free for more than 5 years as of June 2022.

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32-year-old woman with Stage IV rectal cancer, liver and lung metastases, targeted chemotherapy, surgery, ablation, radiation, and ongoing chemotherapy

Patient Info: Anonymized, Female, Under 40 | Stage IV

Biomarkers: KRAS wild-type; NRAS wild-type; BRAF wild-type

Metastatic Site: Liver | Lung | Presacral/perirectal lymph nodes

As of the story endpoint around December 2020, she was 5 years into treatment for Stage IV rectal cancer after multiple systemic regimens, bowel/liver/lung surgery, liver recurrence treatment, ablation, lung surgery, TOMO radiation, and ongoing chemotherapy.

Stage III colon cancer: surgery and treatment story

Patient Info: Anonymized, Female | Stage III

As of June 2022, she had completed colon surgery and 6 months of IV chemotherapy for Stage III colon adenocarcinoma; recurrence, remission, or NED status was not stated.

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Stage III BRCA Ovarian Cancer: Mimi's Survivor Story

Patient Info: Mimi Gallagher, 40s | Stage III

Biomarkers: BRCA-positive

Mimi was cancer-free after surgery and 4 months of intraperitoneal chemotherapy, completed in December 2012.

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Stage IV Breast Cancer: Lise's Patient Story

Patient Info: Lise Pass, Female, 50s | Stage IV

Metastatic Site: bone

Living with metastatic breast cancer for nearly a decade, feeling well and continuing nightly oral chemotherapy after 5 years of monthly infusions.

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Ovarian Cancer Can Present Unique Challenges Around Gender

Patient Info: Anonymized, 40s

At annual follow-up, the ovarian cancer remained in remission with no recurrences since treatment ended in December 2009.

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Stage III signet-ring gastric cancer complicated by a life-threatening aortic fistula after treatment

Patient Info: Anonymized, male, 60s | Stage III

After staged repair of a life-threatening aortoesophageal fistula and later esophageal reconstruction, he was living independently and remained under follow-up without tumor recurrence.

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A young man with metastatic rectal cancer and inherited BRCA1 and MLH1 mutations

Patient Info: Anonymized, Male, Under 40 | Stage IV

Biomarkers: Germline BRCA1 c.4065_4068delTCAA and MLH1 c.232G>T mutations; tumor microsatellite instability-high; loss of MLH1 and PMS2 expression; elevated tumor mutational burden; loss of heterozygosity of wild-type MLH1.

Metastatic Site: liver

The rectal and liver tumors showed a partial response, no viable carcinoma was found in the resected liver lesions, and maintenance nivolumab continued without evidence of growth or recurrence.

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Stage III Ovarian Cancer: Margaret's Patient Story

Patient Info: Margaret Winchester | Stage III

Margaret experienced recurrent small ovarian tumors, underwent cryoablation, and had recently completed another clinical trial while continuing her work.

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Stage IV Colorectal Cancer: Almudena's Survivor Story

Patient Info: Almudena, Female, Under 40 | Stage IV

Metastatic Site: Peritoneum

As of May 2022, Almudena was cancer-free after surgery and 12 chemotherapy sessions, had been medically cleared as cured after 6 years, and continued genetics follow-up because her case was unusual for her age.

Invasive Lobular Carcinoma: Daneen's Survivor Story

Patient Info: Daneen, Female, 50s

Daneen underwent double mastectomy and reconstruction, started radiation and had been taking anastrozole for 2 years when she shared her story.

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Breast Cancer: Kehau's Survivor Story

Patient Info: Kehau Matsumoto, Female, 70+

Kehau had 5 years without a breast cancer recurrence after her 2006 mastectomy, and at the latest report she said she had no signs of cancer.

Stage III Triple-Negative Breast Cancer: Marlena's Patient Story

Patient Info: Marlena Murphy, Female, 40s | Stage III

Biomarkers: triple-negative

Later testing found cancer cells after Marlena noticed a small bump under her right arm. She died on July 3, 2024.

Stage I HR-Positive Breast Cancer: Faye's Patient Story

Patient Info: Faye Ruopp, Female, 60s | Stage I

Biomarkers: ER-positive

Completed lumpectomy and radiation and began long-term hormone therapy in September 2014.

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Colorectal Cancer: Alejandro's Patient Story

Patient Info: Alejandro Mirazo, Male

Biomarkers: Lynch syndrome

Alejandro recovered quickly from colon surgery and had started a planned 4-cycle course of chemotherapy by May 2022, with ongoing surveillance for recurrence and other Lynch syndrome-associated cancers.

Ovarian Cancer: Faye's Patient Story

Patient Info: Faye Belvin, Female

Faye was still receiving the trial combination and said the treatment was working and that she felt better than she had in the previous 2 years.

Metastatic Follicular Carcinoma Arising From Struma Ovarii

Patient Info: Anonymized, Female | Stage Metastatic/Advanced

Metastatic Site: right fallopian tube|peritoneum|omentum|bladder…

Four years after diagnosis, she had no evidence of recurrence or metastasis while continuing thyroid-hormone suppression and 6-monthly surveillance.

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Colon Cancer Returned in a Mesenteric Lymph Node 2 Years After Surgery

Patient Info: Anonymized, Male

The recurrent disease was removed with negative margins in a curative-intent operation. At 8 months, his weight was stable and his energy was improving.

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