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A 40-year-old man with no symptoms underwent routine gastroscopy. The examination found a 20-mm reddish depressed lesion with a surrounding elevation in the upper gastric body. Magnifying endoscopy showed an abnormal vascular pattern, and biopsy confirmed adenocarcinoma.
He underwent endoscopic submucosal dissection. The resected tumor measured 15 x 15 mm and was a moderately differentiated tubular adenocarcinoma confined to the stomach lining. There was no lymphovascular invasion, and both the horizontal and deep resection margins were negative. Tumor testing was positive for Epstein-Barr virus by EBER in situ hybridization, supporting the diagnosis of EBV-associated gastric cancer.
He continued follow-up after the endoscopic treatment. Gastroscopy at 3 months showed no evidence of recurrence. The endoscopic findings at that point showed no detectable disease after complete local resection.
This is a lay summary of an account first published by PMC / PubMed Central. Read the original in full
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