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A 69-year-old man had experienced upper-abdominal discomfort for 6 months when endoscopy found a small raised gastric lesion with an irregular depressed center. Magnifying endoscopy showed an abnormal vascular pattern, and ultrasound suggested that the lesion was mainly confined to the mucosa. Biopsy showed adenocarcinoma with limited differentiation.
He underwent endoscopic submucosal dissection. The removed lesion measured 23 x 18 mm and was diagnosed as moderately to poorly differentiated tubular adenocarcinoma with intramucosal invasion. There was no lymphovascular invasion, and both the horizontal and deep margins were negative. In situ hybridization showed that the tumor cells were positive for Epstein-Barr virus, identifying the cancer as EBV-associated gastric cancer.
He continued endoscopic surveillance after treatment. Gastroscopy 12 months later showed no signs of recurrence.
This is a lay summary of an account first published by PMC / PubMed Central. Read the original in full
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These are lay summaries of published cancer stories, for information only. No two cancers behave the same way, and nothing here predicts your own diagnosis or replaces advice from your oncology team. Read the full disclaimer