Paclitaxel: 361 Real Stories

361 stories match paclitaxel. 359 of them mention chemotherapy.

Harper, who was diagnosed with Stage IV Breast CancerBreast Cancer

Stage IV Breast Cancer: Harper's Patient Story

Patient Info: Harper, Female, 50s | Stage IV

Harper was living with Stage IV breast cancer after self-funded private treatment that included mastectomy, lymphadenectomy, chemotherapy, and radiation therapy; she felt better than before diagnosis but still hoped for complete recovery.

Our Cancer Stories
OutcomeLiving With Cancer
A patient, who was diagnosed with Lung AdenocarcinomaLung Cancer

Recurrent Mucinous Lung Cancer With Dose-Dependent Afatinib Responses

Patient Info: Anonymized, Female, Under 40 | Stage Metastatic/Advanced

Biomarkers: SDC4-NRG1 fusion; PD-L1 not expressed; low tumor mutation burden

Metastatic Site: bilateral lungs

She had progressive lung disease after several targeted-treatment attempts and was receiving paclitaxel with bevacizumab as of February 2020.

PubMed Central
OutcomeCare Ongoing
A patient, who was diagnosed with Stage IV Invasive Ductal CarcinomaBreast Cancer

HER2-positive breast cancer diagnosed during pregnancy and later spread to bone and brain

Patient Info: Anonymized, Female, Under 40 | Stage IV

Biomarkers: Initial tumour: ER 0%, PR <1%, HER2 3+

Metastatic Site: bone (L3)|brain

After treatment and surveillance without new lesions, she developed a large symptomatic occipital brain metastasis 14 months after completing paclitaxel and radiation and died after rapid neurological deterioration.

PubMed Central
OutcomeIn Memory
A patient, who was diagnosed with Stage IV Gastric AdenocarcinomaGastric Cancer

Sjögren syndrome during nivolumab treatment for HER2-positive metastatic gastric cancer

Patient Info: Anonymized, male, 60s | Stage IV

Biomarkers: HER2-positive

Metastatic Site: liver, lungs, adrenal gland

One year after nivolumab was stopped, the shrinkage of lung metastases was maintained and the adrenal metastasis remained unchanged, although severe dry-mouth symptoms from treatment-related Sjögren syndrome persisted.

PubMed Central
OutcomeStable Disease
A patient, who was diagnosed with Invasive Ductal CarcinomaBreast Cancer

Triple-Negative Breast Cancer Treated With Mastectomy and Chemotherapy

Patient Info: Anonymized, Female, 40s

Biomarkers: Triple-negative.

The later accessory-breast-tissue cancer was considered a separate new primary after a five-year interval, and she was currently without evidence of disease.

PubMed Central
OutcomeCancer-Free / NED
A patient, who was diagnosed with Stage IV Gastric CancerGastric Cancer

Graves disease during nivolumab treatment for HER2-positive metastatic gastric cancer

Patient Info: Anonymized, male, 60s | Stage IV

Biomarkers: HER2-positive

Metastatic Site: liver, brain

After progression through several treatment lines and development of brain metastasis, he died 4 months after evaluation for nivolumab-associated Graves disease, more than 1.5 years after his Stage IV gastric-cancer diagnosis.

PubMed Central
OutcomeIn Memory
A patient, who was diagnosed with Invasive Ductal CarcinomaBreast Cancer

HER2-Positive Breast Cancer Linked to a Rare Immune-Related Neurological Syndrome

Patient Info: Anonymized, Female, 40s

Biomarkers: HER2-positive in both foci; one focus ER-negative/PR-positive with Ki-67 45%; second focus ER-negative/PR-negative with Ki-67 35%; anti-Yo antibodies positive in serum and CSF; tumour-susceptibility gene panel negative

At 1 year, she had completed trastuzumab, continued tamoxifen, and had no evidence of recurrent breast cancer; intensive rehabilitation improved her mobility, although balance and right-sided neurological deficits persisted.

PubMed Central
OutcomeCancer-Free / NED
A patient, who was diagnosed with Stage IV Invasive Ductal CarcinomaBreast Cancer

Recurrent Breast Cancer With a Benign-Appearing Chest-Wall Rash

Patient Info: Anonymized, Female | Stage IV

Biomarkers: Initial tumor: ER-positive; PR-negative; HER2-negative.

Metastatic Site: mediastinal lymph nodes

She had recurrent chest-wall and mediastinal metastatic disease; a later rash biopsy showed dermatitis rather than another skin recurrence.

PubMed Central
OutcomeLiving With Cancer
A patient, who was diagnosed with Invasive Ductal CarcinomaBreast Cancer

Heart Failure and Electrical Conduction Changes During Trastuzumab Treatment

Patient Info: Anonymized, Female, 70+

Biomarkers: HER2-positive; ER-positive

Trastuzumab was suspended after acute heart failure and electrical conduction abnormalities; 4 weeks later, left ventricular function recovered and the ECG returned to normal during cardio-oncology follow-up.

PubMed Central
OutcomeNot reported
A patient, who was diagnosed with Ovarian CancerOvarian Cancer

Ovarian Fibrosarcoma Recurring Rapidly After Debulking Surgery

Patient Info: Anonymized, Female, 40s

Biomarkers: Ki-67 greater than 20%; vimentin diffusely positive; muscle-specific antigen weakly positive

The cancer recurred with a new pelvic mass and ascites 3 months after surgery. Her condition was too poor for chemotherapy, and she died on the second day of palliative hospital care.

PubMed Central
OutcomeIn Memory
A patient, who was diagnosed with Stage IV Invasive Ductal CarcinomaBreast Cancer

Young woman with ductal breast cancer and bleeding gastric metastases

Patient Info: Anonymized, Female, Under 40 | Stage IV

Biomarkers: ER-positive; PR-negative; HER2-negative

Metastatic Site: pancreas|liver|kidney|stomach

After rapid progression to the pancreas, liver, kidney and stomach, she chose palliative care and died 1 month after presenting with gastrointestinal bleeding.

PubMed Central
OutcomeIn Memory
Caitlin, who was diagnosed with Stage II Invasive Ductal CarcinomaBreast Cancer

Stage II HR-Positive Invasive Ductal Carcinoma: Caitlin's Patient Story

Patient Info: Caitlin J., Female, Under 40 | Stage II

Biomarkers: ER-positive; PR-positive; BRCA-negative

As of July 2020, Caitlin had completed lumpectomy, AC chemotherapy, Taxol, and 33 radiation treatments for Stage IIB ER-positive, PR-positive IDC and was continuing monthly Lupron plus daily anastrozole.

The Patient Story
OutcomeCare Ongoing
A patient, who was diagnosed with Stage IV Lung CancerLung Cancer

Pleomorphic lung cancer responding to pembrolizumab plus chemotherapy

Patient Info: Anonymized, Male, 60s | Stage IV

Biomarkers: PD-L1 tumor proportion score >75%; EGFR negative; ROS1 negative; ALK fusion negative

Metastatic Site: right 8th rib, left adrenal gland

His general condition improved as the tumors shrank, and he remained well 7 months after diagnosis with maintenance pembrolizumab planned.

PubMed Central
OutcomeResponding Well
MS
Lung Cancer

Multifocal stage IIIA lung adenocarcinoma responding to nivolumab

Patient Info: Anonymized, Female, 60s | Stage III

Biomarkers: CK7-positive; TTF-1-positive; napsin-A-positive; PD-L1 85% positive.

The biopsied lung nodule nearly resolved after four nivolumab cycles, and the remaining pulmonary nodules were stable at 24 months.

PubMed Central
OutcomeResponding Well
Eva, who was diagnosed with Stage IV Breast CancerBreast Cancer

Stage IV Triple-Negative Breast Cancer: Eva's Patient Story

Patient Info: Eva Joseph | Stage IV

Biomarkers: Triple-negative

Metastatic Site: lungs, sternum

On ongoing atezolizumab plus nab-paclitaxel, Eva’s lung and sternum tumors became very small and were being kept at bay while she felt well enough to enjoy short trips.

AACR
OutcomeResponding Well
A patient, who was diagnosed with Stage II Breast CancerBreast Cancer

Triple-negative breast cancer developing beside a large breast cyst

Patient Info: Anonymized, Female, 60s | Stage II

Biomarkers: ER negative; PR negative; HER2 negative; Ki-67 >50%; p53 negative for overexpression, triple negative

She recovered after treatment with no clinical evidence of regional or distant recurrence.

PubMed Central
OutcomeCancer-Free / NED
A patient, who was diagnosed with Stage III Invasive Ductal CarcinomaBreast Cancer

Dramatic chemotherapy response in stage IIIB triple-negative breast cancer

Patient Info: Anonymized, Female, 40s | Stage III

Biomarkers: ER-negative; PR-negative; HER2-negative; BRCA1-negative; BRCA2-negative; germline FLCN c.1285delC associated with Birt-Hogg-Dubé syndrome; tumor TP53 p.T150fs.

Eighteen months after surgery, she had no recurrence following a dramatic chemotherapy response, bilateral mastectomy, chest-wall radiation, and adjuvant capecitabine.

PubMed Central
OutcomeCancer-Free / NED
A patient, who was diagnosed with Stage IV Gastric AdenocarcinomaGastric Cancer

Clival skull-base metastasis during treatment for Stage IV gastric cancer

Patient Info: Anonymized, male, 70+ | Stage IV

Biomarkers: HER2-negative

Metastatic Site: peritoneum, cervical lymph nodes, pelvic bone, lungs,…

At publication he was alive on fourth-line treatment, with no disease progression for 6 months after the clival metastasis was treated and with sustained improvement in his cranial-nerve symptoms.

PubMed Central
OutcomeStable Disease