Gastric cancer recurs in the spermatic cord 7 years after treatment

Patient Info: Anonymized, Male, 40s | Stage IV

Metastatic Site: epididymis, spermatic cord

At 26 months after orchiectomy, he was doing well with no evidence of recurrence, more than 9 years after his original gastric-cancer surgery.

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Sigmoid colon cancer: complete response after repeated metastatic recurrences and multimodal therapy

Patient Info: Anonymized, Male, 60s | Stage IV

Biomarkers: KRAS/NRAS/BRAF status not reported; CEA elevation used for recurrence monitoring

Metastatic Site: left lung, mediastinal lymph nodes, left adrenal…

By 2011, all metastatic lesions had achieved complete response; nearly 1 year after the last adrenal irradiation, no recurrence had been detected.

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Stage III sigmoid colon invasive micropapillary carcinoma treated with sigmoidectomy and modified FOLFOX6

Patient Info: Anonymized, Male, 70+ | Stage III

Biomarkers: CEA normal; CA 19-9 normal; MUC1 inside-out staining pattern in micropapillary component

After diagnostic endoscopic resection, sigmoidectomy with regional lymph node resection, and 6 cycles of modified FOLFOX6, he was in good condition with no evidence of recurrence 12 months after surgery.

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Sigmoid colon cancer with later inguinal lymph-node metastasis: surgery, FOLFOX, FOLFIRI, and cetuximab

Patient Info: Anonymized, Male, 60s | Stage IV

Biomarkers: CEA was elevated at diagnosis and recurrence. Metastatic lymph node was CK20 positive/CK7 negative; EGFR mutation status not reported.

Metastatic Site: left inguinal lymph node

Apparently disease-free 8 months after surgical removal of the left inguinal lymph-node metastasis followed by FOLFIRI plus cetuximab.

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