Stage III Colorectal Cancer: Amanda's Survivor Story

Patient Info: Amanda Peters, Female, 40s | Stage III

Biomarkers: No genetic markers reported

As of September 2023, Amanda reported no recurrence about 3 years after Stage IIIB rectal cancer surgery and adjuvant chemotherapy, with surveillance CT scans now yearly.

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Stage IV Colorectal Cancer: Keith's Patient Story

Patient Info: Keith, Male, 40s | Stage IV

Metastatic Site: Liver; lymph nodes; lungs

As of September 2023, Keith was on third-line treatment for Stage IV colon cancer with lung metastases, small lung lesions under 1 cm, a low tumor marker after 2 rounds, and possible trial/transplant options after standard care.

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Rectal Cancer Treated With Radiation, FOLFOX and Surgery in a Woman With a Separate Breast Cancer

Patient Info: Anonymized, female, 60s

Surgery showed only minimal residual rectal adenocarcinoma with clear margins, and later follow-up described both of her cancers as appearing in remission.

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Colorectal cancer causing severe hip/back pain and kidney swelling

Patient Info: Anonymized, Male | Stage IV

Biomarkers: MLH1, MSH2, MSH6 and PMS2 expression retained; metastatic cells CK20-

Metastatic Site: distant lymph nodes; left psoas muscle /…

He had active metastatic colorectal cancer with malignant psoas syndrome; his condition worsened after the second palliative FOLFOX cycle and chemotherapy was discontinued.

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Stage IV Colorectal Cancer: Michelle's Survivor Story

Patient Info: Michelle Cappel, Female, 40s | Stage IV

Biomarkers: Lynch syndrome negative; no hereditary genetic markers reported

Metastatic Site: Ovary

As of July 2023, Michelle had achieved no evidence of disease after FOLFOX chemotherapy and 12-hour surgery for Stage IV colorectal cancer with ovarian metastasis, while continuing to live with scan anxiety and surveillance.

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My Colorectal Cancer Story: How I Changed My Diet After Cancer

Patient Info: Angelica Allen, Female, Under 40 | Stage III

As of June 2023, Angelica was all-clear after 5 years following Stage III bowel cancer treatment and described survivorship changes in diet, exercise, rest, stress, and emotional healing.

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Stage III Colorectal Cancer: Angelica's Survivor Story

Patient Info: Angelica Allen, Female, Under 40 | Stage III

As of June 2023, Angelica had received her 5-year all-clear after Stage III bowel cancer treatment; later colonoscopy surveillance was reassuring and a liver cyst had disappeared.

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My Stage 4 Colorectal Cancer Story: How I Never Lost Hope

Patient Info: Jason Randall, Male | Stage IV

Metastatic Site: Liver; lungs; bone/sacrum

As of June 2023, Jason had a negative Signatera test, CT scans showing 9 months with no evidence of disease, and about 2.5 years off chemotherapy after Stage IV colorectal cancer treatment and lung ablation.

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Gastric cancer and a large abdominal aortic aneurysm treated in one operation

Patient Info: Anonymized, male, 50s | Stage III

At 1-year follow-up, CT and upper endoscopy showed no local or distant recurrence.

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Stage IV Colorectal Cancer: Bart's Survivor Story

Patient Info: Bart Wilson, Male, Under 40 | Stage IV

Metastatic Site: Liver

As of May 2023, Bart had shown no evidence of disease for almost 3 years after surgery, FOLFOX, portal vein embolization, extended right hepatectomy, and adjuvant capecitabine for Stage IV colon cancer with liver metastases.

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I was in Disbelief When I got Colon Cancer

Patient Info: JJ Singleton, Male, Under 40 | Stage IV

Biomarkers: Lynch syndrome

Metastatic Site: Abdominal wall; lymph nodes

After surgery and 12 rounds of FOLFOX, JJ had a clean scan and colonoscopy, but about 6 weeks later cancer recurred outside the colon with spread to the abdominal wall and lymph nodes.

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Stage III Colorectal Adenocarcinoma: Ashley's Patient Story

Patient Info: Ashley | Stage III

Ashley continues chemotherapy with Xeloda after surgery and 8 rounds of FOLFOX.

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Stage III Colorectal Cancer: Gina's Patient Story

Patient Info: Gina | Stage III

The cancer returned in March near the original area. Gina completed radiation in August and was awaiting scans, with FOLFOX planned for November 2024.

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Stage III Colorectal Adenocarcinoma: Laura's Patient Story

Patient Info: Laura | Stage III

Laura completed about 6 months of chemotherapy after partial colectomy and returned to part-time work while continuing to manage fatigue.

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32-year-old woman with Stage IV rectal cancer, liver and lung metastases, targeted chemotherapy, surgery, ablation, radiation, and ongoing chemotherapy

Patient Info: Anonymized, Female, Under 40 | Stage IV

Biomarkers: KRAS wild-type; NRAS wild-type; BRAF wild-type

Metastatic Site: Liver | Lung | Presacral/perirectal lymph nodes

As of the story endpoint around December 2020, she was 5 years into treatment for Stage IV rectal cancer after multiple systemic regimens, bowel/liver/lung surgery, liver recurrence treatment, ablation, lung surgery, TOMO radiation, and ongoing chemotherapy.

A young man with metastatic rectal cancer and inherited BRCA1 and MLH1 mutations

Patient Info: Anonymized, Male, Under 40 | Stage IV

Biomarkers: Germline BRCA1 c.4065_4068delTCAA and MLH1 c.232G>T mutations; tumor microsatellite instability-high; loss of MLH1 and PMS2 expression; elevated tumor mutational burden; loss of heterozygosity of wild-type MLH1.

Metastatic Site: liver

The rectal and liver tumors showed a partial response, no viable carcinoma was found in the resected liver lesions, and maintenance nivolumab continued without evidence of growth or recurrence.

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Stage II Colorectal Adenocarcinoma: Michael's Survivor Story

Patient Info: Michael | Stage II

Declared cancer-free in July 2024 after surgery, chemotherapy and radiation.

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Stage IV HER2-Positive Gastric Cancer: Bryan's Patient Story

Patient Info: Bryan Chagolla, Male, Under 40 | Stage IV

Biomarkers: HER2-positive

Metastatic Site: liver

Bryan had a strong response to trastuzumab deruxtecan in 2021. He died on May 13, 2022, surrounded by loved ones.

Colorectal Cancer: Barbara's Survivor Story

Patient Info: Barbara, Female, 40s

As of October 2021, Barbara described life after completed colon-cancer treatment, including survivorship, parenting, and a stronger perspective; recurrence was not described in this edited video.

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A Severe Delayed Immune Reaction After Treatment for Metastatic Colon Cancer

Patient Info: Anonymized, Male, 70+ | Stage IV

Metastatic Site: liver

He recovered from repeated episodes of severe cytokine release syndrome after prolonged corticosteroids, completed adjuvant FOLFOX and CV301 without nivolumab, and had no further CRS episodes.

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Severe immune thrombocytopenia during treatment for metastatic colon cancer

Patient Info: Anonymized, Female, 50s | Stage IV

Biomarkers: KRAS-mutated; microsatellite stable; BRAF-wild type.

Metastatic Site: bilateral ovaries; pelvis; peritoneum; mesenteric…

After multiple metastatic recurrences and treatment changes, she died from progressive colon cancer; oxaliplatin had been permanently stopped after antibody-confirmed immune thrombocytopenia.

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Stage IV Colorectal Cancer: Lee's Survivor Story

Patient Info: Lee Jones, Male, 50s | Stage IV

Metastatic Site: Liver

As of February 2021, Lee reported no evidence of colon cancer since 2011 after treatment for Stage IV colon cancer with liver metastases, recurrence, chemotherapy, colon surgery, and liver surgery.

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Stage IV Colorectal Cancer: Maria's Patient Story

Patient Info: Maria | Stage IV

Metastatic Site: lungs

After colorectal cancer spread to the lungs, completed 6 months of chemotherapy and is being monitored with CT scans every 3 months.

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Stage IV Colorectal Adenocarcinoma: Amanda's Patient Story

Patient Info: Amanda, Under 40 | Stage IV

She remains on ongoing treatment for Stage IV disease and describes the cancer as pretty stable while maintaining a good quality of life.

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