Portal-vein thrombosis after surgery and chemotherapy for Stage III gastric cancer — Case 1

Patient Info: Anonymized, female, 40s | Stage III

At 6 months of follow-up after treatment for the thrombosis, no hepatic decompensation or liver cirrhosis had developed.

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Portal-vein thrombosis after surgery and chemotherapy for Stage III gastric cancer — Case 2

Patient Info: Anonymized, female, 60s | Stage III

Two months into follow-up after the thrombosis, no hepatic decompensation or liver cirrhosis had been identified.

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Gastric cancer diagnosed during late pregnancy after severe gastrointestinal bleeding

Patient Info: Anonymized, female, 40s

Biomarkers: HER2-negative

Six months after emergency surgery, chemotherapy and radiation were still ongoing.

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Gastric cancer with an unexpected appendix metastasis

Patient Info: Anonymized, female, 50s | Stage IV

Metastatic Site: appendix

PET/CT at 6, 12 and 18 months showed no recurrence, giving at least 18 months with no evidence of disease after treatment.

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Stage III Gastric Cancer: Abdul's Patient Story

Patient Info: Abdul | Stage III

Abdul later stopped further treatment and focused on spending meaningful time with family while living with gastric cancer.

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Stage I Gastric Adenocarcinoma: Kaisu's Survivor Story

Patient Info: Kaisu, female | Stage I

Kaisu reported being cancer-free since November 2020 after chemotherapy and total gastrectomy, while continuing to manage lasting treatment and surgery effects.

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Primary gastric squamous cell carcinoma with early chest metastases

Patient Info: Anonymized, male, 60s | Stage IV

Biomarkers: HER2-negative

Metastatic Site: lungs, distant lymph nodes

Twelve months after chemotherapy began, the metastatic chest lesions had not progressed and showed minor regression.

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Gastric Choriocarcinoma With Adenocarcinoma and Rapid Liver Metastases After Surgery

Patient Info: Anonymized, female, 70+ | Stage IV

Biomarkers: β-hCG positive; serum β-hCG 972.1 mIU/mL after diagnosis

Metastatic Site: liver

Multiple liver metastases appeared 2 months after discharge, and she died from hepatic failure 5 months after surgery.

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Recovery from a severe duodenal fistula after gastric cancer surgery

Patient Info: Anonymized, male, 70+ | Stage III

He was in good health with no recurrence or metastasis 2 years after the original gastric-cancer surgery.

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Mixed adenocarcinoma-neuroendocrine gastric cancer progressing after multiple treatments

Patient Info: Anonymized, male, 60s | Stage IV

Biomarkers: HER2-negative

Metastatic Site: liver

After progression through several treatments and development of liver metastasis, he was taking apatinib at the latest update.

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Gastric cancer causing outlet obstruction and esophageal perforation

Patient Info: Anonymized, male, 60s

After nearly 3 months in hospital, he was eating a regular diet and walking independently and had been referred for adjuvant oncology evaluation.

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Stage III Gastric Cancer: Holly's Patient Story

Patient Info: Holly Clegg, Female | Stage III

She was receiving hospice support at home while continuing gastric-cancer advocacy and fundraising.

Gastric Cancer: Brian's Survivor Story

Patient Info: Brian

Brian reported being declared cancer-free in June 2022 after a partial gastrectomy and continued follow-up with medical teams.

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Perforated gastric cancer treated with staged surgery, HIPEC and chemotherapy

Patient Info: Anonymized, male, 60s

Adjuvant capecitabine plus oxaliplatin began one month after surgery. At the 6-month follow-up, he was eating without discomfort and had no other symptoms.

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Severe dumping syndrome after gastrectomy for gastric cancer

Patient Info: Anonymized, Male, 60s

A 68-year-old man developed severe early dumping syndrome with shock after a previous total gastrectomy for gastric cancer.

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EBV-associated gastric cancer recurring after endoscopic resection in a woman with CTLA4 insufficiency

Patient Info: Anonymized, female, 40s

Biomarkers: CTLA4 mutation; EBV-associated

She reached complete remission after total gastrectomy for the recurrence and was about 3 years beyond that surgery at the latest description.

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In situ gastric adenocarcinoma treated endoscopically in a man with CTLA4 insufficiency

Patient Info: Anonymized, male, 40s

Biomarkers: CTLA4 mutation; EBV-associated

Six months after endoscopic resection, gastroscopy showed quiescent tubular adenomas with low-grade dysplasia and ongoing endoscopic surveillance was planned.

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Gastric adenocarcinoma treated with total gastrectomy in a man with CTLA4 insufficiency

Patient Info: Anonymized, male, Under 40

Biomarkers: CTLA4 mutation

He died from Klebsiella pneumonia sepsis 25 months after total gastrectomy.

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Teenage-onset gastric adenocarcinoma followed by 7 years of complete remission

Patient Info: Anonymized, male, Under 40

Biomarkers: CTLA4 mutation; EBV-negative

He remained in complete remission for 7 years after total gastrectomy.

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Poorly differentiated gastric cancer treated surgically in a woman with CTLA4 insufficiency

Patient Info: Anonymized, female, Under 40

Biomarkers: CTLA4 mutation; EBV-negative

She had no gastric-cancer relapse for more than 3 years after subtotal gastrectomy.

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AFP-producing hepatoid gastric cancer with neuroendocrine differentiation

Patient Info: Anonymized, male, 60s

Biomarkers: AFP-producing; synaptophysin-positive; chromogranin A-positive

At 6 months after surgery, AFP had risen above 2,000 ng/mL while CT showed no obvious abnormality. He declined PET/CT and left the hospital.

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Managing severe hypothyroidism before surgery for obstructing gastric cancer

Patient Info: Anonymized, Male, 50s

A 53-year-old man with an obstructing gastric adenocarcinoma needed urgent correction of severe hypothyroidism before cancer surgery could proceed.

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Hereditary diffuse gastric cancer in a 34-year-old man with a CDH1 mutation

Patient Info: Anonymized, Male, Under 40 | Stage III

Biomarkers: CDH1 monoallelic deletion of exons 1-2

Under surveillance with the most recent CT showing no active disease and no evidence of disease at the latest follow-up.

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Microscopic gastric cancer found after preventive gastrectomy in a 32-year-old man with a CDH1 mutation

Patient Info: Anonymized, Male, Under 40

Biomarkers: CDH1 monoallelic deletion of exons 1-2

Recovered after a postoperative pancreatitis episode and was doing well without evidence of disease at the latest follow-up.

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