Managing severe hypothyroidism before surgery for obstructing gastric cancer

This gastric cancer diagnosis at a glance

Subtype
Adenocarcinoma
Sex
Male
Treatment
surgery

Treatment course, step by step

  1. Underwent subtotal gastrectomy with Roux-en-Y gastrojejunostomy and lymph-node dissection.

What happened, in summary

A 53-year-old man with long-standing hypothyroidism developed progressive upper-abdominal pain and repeated vomiting. Endoscopy found a large ulcerating mass that completely blocked the gastric outlet, and biopsy confirmed gastric adenocarcinoma. Staging CT showed that the cancer was considered surgically resectable.

Before major surgery, however, his severe hypothyroidism created an additional safety concern. Because the obstruction prevented reliable absorption of his usual oral levothyroxine and injectable treatment was not immediately available, the medical team tried alternative thyroid-hormone delivery, including rectal levothyroxine enemas. Higher-dose rectal treatment eventually restored his thyroid hormone levels sufficiently for surgery.

On hospital day 19, he underwent subtotal gastrectomy with Roux-en-Y gastrojejunostomy and lymph-node dissection. Intravenous thyroid hormone became available for the immediate postoperative period.

Where this story comes from

This is a lay summary of an account first published by PMC / PubMed Central. Read the original in full

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