Rectal cancer surgery followed by treatment for severe anastomotic narrowing

Patient Info: Anonymized, female, 50s

After rectal-cancer surgery, a woman developed severe anastomotic narrowing that was treated with a minimally invasive magnetic technique.

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Colorectal Cancer: Kristen's Patient Story

Patient Info: Kristen Van de Geer, Female, 40s

Chemotherapy was complete, and she was focused on physical recovery after treatment.

Dana-FarberRead more →

Regorafenib produced a radiologic complete response in metastatic colon cancer with lung metastases

Patient Info: Anonymized, male, 60s | Stage IV

Biomarkers: KRAS codon 146 mutation; BRAF wild type; MSI-low

Metastatic Site: liver, lung

Nine months after stopping regorafenib, CT showed scarring of the lung metastases consistent with a radiologic complete response.

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Stage III Colorectal Cancer: Katie's Patient Story

Patient Info: Katie LaPira, Female, 40s | Stage III

Katie described herself as in the middle of her Stage III colon cancer journey after surgery, with 6 months of oral and intravenous chemotherapy recommended.

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Stage IV Colorectal Cancer: Bobbi's Survivor Story

Patient Info: Bobbi Ratliff, 50s | Stage IV

Metastatic Site: liver|lungs

On February 1, 2024, scans showed no evidence of cancer after multimodal treatment for Stage IV disease.

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Pembrolizumab produced a complete response in unresectable dMMR colon cancer

Patient Info: Anonymized, female, 70+

Biomarkers: dMMR/MSI-H; MLH1 loss; MSH2 loss; RAS/BRAF wild type; MLH1 promoter hypermethylation

Surgery found a pathological complete response with no residual cancer in the colon or 58 lymph nodes, and follow-up showed no relapse.

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Pembrolizumab enabled complete response and surgery for unresectable dMMR colon cancer

Patient Info: Anonymized, male, 60s

Biomarkers: dMMR/MSI-H; MLH1 loss; PMS2 loss; BRAF mutation; MLH1 promoter hypermethylation

The surgical specimen showed a pathological complete response with no residual cancer and 0 of 43 lymph nodes involved, and follow-up showed no relapse.

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Pembrolizumab and surgery for metastatic dMMR colorectal cancer with major response

Patient Info: Anonymized, female, 50s | Stage IV

Biomarkers: dMMR/MSI-H; MLH1 loss; PMS2 loss; BRAF/RAS wild type; RET::NCOA4 fusion; MLH1 promoter hypermethylation

Metastatic Site: non-regional lymph nodes

Surgery showed a major pathological response with less than 10% viable tumor. Pembrolizumab was restarted after surgery, and no relapse had been documented.

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Pembrolizumab led to complete response before surgery for metastatic dMMR colon cancer

Patient Info: Anonymized, male, 70+ | Stage IV

Biomarkers: dMMR/MSI-H; MLH1 loss; PMS2 loss; BRAF mutation; heterozygous MUTYH p. pathogenic variant

Metastatic Site: liver

The 2023 liver resection showed a pathological complete response with no residual tumor, and he entered follow-up without additional therapy.

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Stage IV colon cancer treated with FOLFOX during hemodialysis

Patient Info: Anonymized, male, 70+ | Stage IV

Biomarkers: RAS mutation; BRAF wild type

Metastatic Site: lung

Cancer was controlled during chemotherapy for a period, but modified FOLFOX was ultimately stopped because the disease progressed.

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Stage IV rectal cancer treated with multiple chemotherapy lines during hemodialysis

Patient Info: Anonymized, female, 70+ | Stage IV

Biomarkers: RAS mutation; BRAF wild type

Metastatic Site: liver

Modified FOLFOX was stopped after 6 cycles because the metastatic rectal cancer progressed.

PubMed CentralRead more →

Stage IV Colorectal Cancer: Cristina's Survivor Story

Patient Info: Cristina Patrick, Female | Stage IV

Metastatic Site: ovary

Cristina reported no evidence of disease since June 2021 after surgery and 6 months of chemotherapy for metastatic colon cancer.

Fight Colorectal CancerRead more →

Stage III Colorectal Cancer: Jena's Patient Story

Patient Info: Jena Sica, Under 40 | Stage III

Biomarkers: Biomarker testing completed; results not reported

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Stage III Colorectal Cancer: Jelena's Survivor Story

Patient Info: Jelena, Female, Under 40 | Stage III

As of January 2024, Jelena was on annual follow-up after Stage III rectal cancer treatment, with her latest colonoscopy showing no polyps or suspicious findings.

The Patient StoryRead more →

Colorectal Cancer: Ann's Survivor Story

Patient Info: Ann Gustafson, 40s

Biomarkers: No genetic markers identified on biomarker testing; specific panel not reported

After colon resection and chemotherapy, Ann described feeling stronger and healthier than when treatment began; current recurrence status was not stated.

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Stage II Colorectal Cancer: Kara's Patient Story

Patient Info: Kara Wutzke | Stage II

After chemotherapy, surgery, a temporary ileostomy, and reversal, Kara focused on gradually rebuilding her fitness, strength, and sense of self.

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Stage III Colorectal Cancer: Stacy's Survivor Story

Patient Info: Stacy Hughes, Under 40 | Stage III

Stacy completed 8 rounds of chemotherapy after surgery and reported being cancer-free.

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Stage II Colorectal Cancer: Jay's Survivor Story

Patient Info: Jay McCoy, Male, 40s | Stage II

As of January 2024, Jay had made a full recovery after Stage II colon cancer was found early by colonoscopy and treated surgically, with normal numbers at his second annual physical in June 2023.

Cleveland ClinicRead more →

Stage IV Colorectal Cancer: Jim's Patient Story

Patient Info: Jim Bromwich, Male, Under 40 | Stage IV

Metastatic Site: Lung

As of January 2024, he had completed focused radiation to an isolated lung nodule and was awaiting follow-up scans; another tiny lung nodule was being monitored but was not PET-avid.

The Patient StoryRead more →

Stage III Colorectal Cancer: Marianne's Survivor Story

Patient Info: Marianne | Stage III

Declared cancer-free in 2025 after surgery and an abbreviated chemotherapy course.

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Rectal signet ring cell cancer with an unusual metastasis into a lipoma

Patient Info: Anonymized, male, 40s | Stage IV

Metastatic Site: subcutaneous abdominal wall lipoma, peritoneum

Peritoneal carcinomatosis developed during adjuvant FOLFOX. Second-line chemotherapy was proposed, and he died 12 months later.

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Stage III Colorectal Adenocarcinoma: Marissa's Patient Story

Patient Info: Marissa | Stage III

Still in active treatment at the time of the story after surgery and chemotherapy, with 15 radiation sessions delivered in September 2025.

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Stage II Colorectal Adenocarcinoma: Keith's Patient Story

Patient Info: Keith | Stage II

After surgery, no lymph nodes were positive and his latest scan showed nothing of concern.

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Colorectal Cancer: Bridget's Survivor Story

Patient Info: Bridget

Bridget was declared cancer-free in 2025.

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