Lobular breast cancer with extraocular muscle and lung metastases: ocular improvement after radiotherapy and tamoxifen

Patient Info: Anonymized, Female, 60s | Stage IV

Biomarkers: Original breast cancer: ER-negative; PR-negative. Extraocular muscle metastasis/recurrent disease: ER strongly positive; PR strongly positive.

Metastatic Site: bilateral extraocular muscles, right upper lobe lung,…

At 18 months after presentation with extraocular muscle metastases, PET showed no abnormality, diplopia had resolved, and ocular motility had markedly improved, with mild bilateral ptosis remaining.

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Triple-negative glycogen-rich clear cell carcinoma of the breast: chemotherapy, mastectomy, and radiation

Patient Info: Anonymized, Female, 50s | Stage III

Biomarkers: Triple-negative breast cancer with glycogen-rich clear cell features; pathology stains supported breast carcinoma.

Asymptomatic and disease-free 14 months after surgery, additional chemotherapy, and 50 Gy radiotherapy for T4N0M0 triple-negative glycogen-rich clear cell breast carcinoma.

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Male invasive papillary breast cancer: mastectomy and tamoxifen with 2-year well status

Patient Info: Anonymized, Male, 70+ | Stage I

Biomarkers: ER-positive; HER2 not over-amplified

Recovered after mastectomy and sentinel node biopsy, received adjuvant tamoxifen, and remained well 2 years after surgery.

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Male invasive ductal breast cancer treated with mastectomy and tamoxifen

Patient Info: Anonymized, Male, 70+

Biomarkers: ER-positive

Treated with mastectomy, negative sentinel lymph node biopsy, and adjuvant tamoxifen; remained well 4 years after surgery.

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Cutaneous granular cell tumor of the breast: no recurrence after complete excision

Patient Info: Anonymized, Female, 70+

Biomarkers: and CD68; ER/PR negative; low Ki-67.

As of August 2010, the cutaneous granular cell tumor had been completely excised, with no evidence of recurrence in the left breast after 4 years of follow-up.

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ER-positive breast cancer recurrence after DCIS: chemotherapy, nodal surgery, radiation, and endocrine therapy

Patient Info: Anonymized, Female, 40s

Biomarkers: Recurrent invasive breast cancer: ER-positive; HER2/neu-negative. PR not reported.

Disease-free for 33 months after treatment of ER-positive, HER2-negative invasive breast cancer recurring in the mastectomy skin flap with positive axillary sentinel nodes.

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Male ER/PR-positive breast cancer with contralateral DCIS: mastectomy and tamoxifen with no recurrence

Patient Info: Anonymized, Male, 60s

Biomarkers: Left breast cancer was ER+/PR+ with weak HER2. Right breast had intermediate-grade DCIS; no node spread reported.

Well with no evidence of locoregional recurrence after 5 years of follow-up on adjuvant tamoxifen after bilateral breast surgery.

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Localized breast carcinosarcoma: surgery and chemotherapy with no disease at 54 months

Patient Info: Anonymized, Female, 40s

Biomarkers: Breast carcinosarcoma was ER/PR negative, c-erbB2 5%

Under follow-up with no disease at 54 months after excision, modified radical mastectomy, and 6 courses of chemotherapy for localized breast carcinosarcoma.

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HER2-positive breast cancer with isolated adrenal metastasis: adrenalectomy with no recurrence at follow-up

Patient Info: Anonymized, Female, 60s | Stage IV

Biomarkers: Primary breast tumor and adrenal metastasis were HER2-positive and ER/PR negative; adrenal markers supported breast origin.

Metastatic Site: left adrenal gland

Alive in good condition with no evidence of recurrence more than 3 years after adrenalectomy for isolated adrenal metastasis and more than 5 years after the original breast surgery.

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Stage IV Breast Cancer: Su's Patient Story

Patient Info: Su Chiao | Stage IV

Metastatic Site: bones, thymus, liver

After 7 years, the breast cancer had spread to the bones and thymus, and more recently it spread to the liver, where she underwent embolization.

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Stage II Breast Cancer: Martha's Survivor Story

Patient Info: Martha | Stage II

Martha completed treatment and said she had been declared cancer-free, 14 years after her stage II diagnosis.

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Stage I BRCA1 Breast Cancer: Karen's Patient Story

Patient Info: Karen | Stage I

Biomarkers: BRCA1 mutation

Karen completed surgery and chemotherapy for stage 1 breast cancer and chose prophylactic bilateral mastectomy because of a BRCA1 mutation, while continuing to live with fear of recurrence.

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Stage 0 Breast Cancer: Linda's Survivor Story

Patient Info: Linda | Stage 0

Linda completed lumpectomy, chemotherapy, and radiation after a stage 0 diagnosis in 2007 and described the cancer as being in remission years later.

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Stage III Breast Cancer: Mary's Survivor Story

Patient Info: Mary | Stage III

Mary said she was in remission and no longer required cancer treatment.

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