BRCA2 Breast Cancer: Erika's Patient Story

Patient Info: Erika, Female, Under 40

Biomarkers: BRCA2 mutation

As of June 2026, Erika had no cancer diagnosis after a BRCA2-positive result and preventive double mastectomy with implant reconstruction, with ongoing hereditary-risk surveillance.

The Patient StoryRead more →

Stage III HR-Positive Invasive Lobular Carcinoma: Tina's Patient Story

Patient Info: Tina, Female, Under 40 | Stage III

Biomarkers: ER-positive

As of June 2026, Tina was in survivorship after double mastectomy, AC-T chemotherapy, radiation, and ongoing hormone therapy with daily tamoxifen and Zoladex every 3 months.

The Patient StoryRead more →

Stage III HER2-Positive Breast Cancer: Genoa's Survivor Story

Patient Info: Genoa M., Female | Stage III

Biomarkers: HER2-positive; ER-positive

As of June 2026, Genoa had completed treatment for Stage III HER2-positive, ER-positive breast cancer with neoadjuvant Taxotere/carboplatin/trastuzumab, lumpectomy, and radiation, and was focused on survivorship and rebuilding life after treatment.

The Patient StoryRead more →

Stage I HR-Positive Invasive Ductal Carcinoma: Amelia's Patient Story

Patient Info: Amelia, Female, 40s | Stage I

Biomarkers: ER-positive; PR-positive; HER2-negative; BRCA negative; Oncotype DX score 22

As of June 2026, Amelia had no evidence of disease after lumpectomy, bilateral mastectomy, TC chemotherapy, and reconstruction, and she remained on tamoxifen.

The Patient StoryRead more →

Metastatic triple-negative breast cancer with orbital and bone metastases responding to nab-paclitaxel plus everolimus

Patient Info: Anonymized, Female, 70+ | Stage IV

Biomarkers: Primary breast cancer was ER-low, PR/HER2 negative. Orbital metastasis was triple-negative with AKT1 exon 4 mutation.

Metastatic Site: right orbit/orbital mass; bone

At 6-month follow-up, systemic disease was stable, ocular symptoms had significantly improved, orbital metastases were stable on MRI, and the response was described as RECIST partial response/progression-free interval while treatment continued.

PubMed CentralRead more →

Amy’s Stage 4 Hormone-Positive Lobular Breast Cancer Story

Patient Info: Amy, Female | Stage IV

Biomarkers: ER-positive; PR-positive; HER2-negative

Metastatic Site: Spine; pelvis

Amy was living with de novo stage 4 lobular breast cancer involving the spine and pelvis and remained active in rural-patient advocacy.

Lobular Breast Cancer AllianceRead more →

Stage IIB triple-negative metaplastic breast cancer with early metastatic recurrence: durable response to pembrolizumab-based therapy

Patient Info: Anonymized, Female, 50s | Stage IV

Biomarkers: Triple-negative metaplastic breast cancer with PD-L1 CPS 83.2, BRCA1/2 negative

Metastatic Site: lung, sternum

As of May 2026, she had more than 30 months of disease control after pembrolizumab-based therapy for early recurrent metastatic metaplastic breast cancer, with only mild residual sternal uptake and no disease progression.

PubMed CentralRead more →

Stage IV BRCA Breast Cancer: Maralee's Survivor Story

Patient Info: Maralee, Female, Under 40 | Stage IV

Biomarkers: BRCA mutation

Metastatic Site: Brain

As of May 2026, Maralee had no evidence of active disease after prior Stage IV breast cancer with brain metastasis, had stopped the PARP inhibitor after 2 years, remained without brain recurrence long enough to pursue pregnancy, and gave birth to a second daughter.

Cleveland ClinicRead more →

Stage ypT1aN0 triple-negative breast cancer with familial BRCA1 and OBSCN deletions

Patient Info: Anonymized, Female, Under 40

Biomarkers: Triple-negative breast cancer; HER2 1+/negative; Ki-67 20%+. Familial testing showed BRCA1 and OBSCN deletions.

She underwent modified radical mastectomy with sentinel lymph node dissection and continued postoperative follow-up, with the main clinical emphasis on familial BRCA1/OBSCN genetic susceptibility.

PubMed CentralRead more →

Stage I luminal A invasive ductal breast cancer with post-treatment cognitive symptoms

Patient Info: Anonymized, Female, 70+ | Stage I

Biomarkers: ER 100% positive; PR 95% positive; HER2 score 0 / HER2-negative; Ki-67 10%; P63 negative

As of April 2026, the case focused on survivorship after Stage I luminal A breast cancer treatment, with cognitive complaints after chemotherapy and improved MoCA and depression scores after 12 sessions of tDCS; brain metastases had been ruled out.

PubMed CentralRead more →

Stage II Breast Cancer: Jenna's Patient Story

Patient Info: Jenna, Female, Under 40 | Stage II

Biomarkers: Hormone receptor-positive; HER2-negative; BRCA inherited gene mutations negative

As of April 2026, Jenna had completed pregnancy-associated chemotherapy and double mastectomy for Stage II HR-positive, HER2-negative breast cancer with 1 involved lymph node, did not need radiation, and was on hormone therapy for 10 years.

Breast Cancer: Muriel's Patient Story

Patient Info: Muriel, Female

As of 16 April 2026, Muriel was in the antihormonal-therapy phase, living largely symptom-free after breast surgery and chemotherapy, and supporting other people with cancer as a peer counselor.

Stage IV Breast Cancer: Erica's Patient Story

Patient Info: Erica, Female, 40s | Stage IV

Biomarkers: Hormone-positive; HER2-negative

Metastatic Site: Bone — ribs, sternum, spine, femur/right hip, shoulder…

Living with stable Stage IV hormone-positive, HER2-negative metastatic breast cancer involving multiple bones, currently managed with monthly hormone-suppressant injections and monitoring.

The Patient StoryRead more →

Invasive Lobular Carcinoma: Liz's Survivor Story

Patient Info: Liz O’Riordan, Female, 40s

Technically cancer-free after 2 local recurrences, with no metastatic disease stated, while continuing lifelong monthly injection treatment to reduce the risk of metastatic disease and living with scanxiety.

The Patient StoryRead more →

Triple-Negative Breast Cancer: Jes's Survivor Story

Patient Info: Jes, Female

Biomarkers: ER-negative; PR-negative; HER2-negative

No evidence of disease after chemotherapy/immunotherapy and bilateral mastectomy; no positive lymph nodes were found, chemotherapy cleared the cancer, and radiation was not needed, though she continued to experience long-term treatment effects.

The Patient StoryRead more →

Hormone receptor-positive high-grade encapsulated papillary breast carcinoma with limited invasion

Patient Info: Anonymized, Female, 40s

Biomarkers: ER/PR-positive, HER2-negative breast cancer; Ki-67 high in papillary/high-grade invasive areas; sentinel lymph nodes negative.

After mastectomy, sentinel-node evaluation, S-1, and endocrine therapy, she remained disease-free and in good health under regular follow-up.

PubMed CentralRead more →

Triple-Negative Breast Cancer: Marina's Survivor Story

Patient Info: Marina, Female, Under 40

Biomarkers: BRCA1 mutation; triple-negative breast cancer

Triple-negative breast cancer survivor with a BRCA1 mutation who completed treatment after an initial diagnosis and a second diagnosis at the 5-year mark; no formal stage or metastatic disease was stated in the available source text.

The Patient StoryRead more →

Breast cancer treated separately from concurrent diffuse large B-cell lymphoma

Patient Info: Anonymized, Female, 50s

Biomarkers: ER-positive; PR-positive; HER2-positive

Follow-up after mastectomy showed no local recurrence of the breast cancer.

PubMed CentralRead more →

Metastatic invasive lobular breast cancer with stomach, ovarian, peritoneal, rectal, and jejunal spread

Patient Info: Anonymized, Female, 40s | Stage IV

Biomarkers: Primary tumor and gastric metastasis were ER/PR positive and HER2 negative; GATA3 supported breast origin in the metastasis.

Metastatic Site: stomach; ovaries; peritoneum; rectum; jejunum

During 2025, she remained under active oncologic management for metastatic invasive lobular breast cancer with gastrointestinal, ovarian, peritoneal, rectal, and jejunal involvement.

PubMed CentralRead more →

ER-positive/HER2-positive breast cancer with rare paranasal sinus and skull metastasis

Patient Info: Anonymized, Female, 70+ | Stage IV

Biomarkers: Primary and paranasal sinus metastasis were ER positive, PR negative, HER2 positive; GATA3 supported breast origin in metastasis.

Metastatic Site: left frontal sinus; ethmoid air cells; posterior…

The paranasal sinus/skull metastasis did not respond to palliative radiotherapy; her condition deteriorated and she died 2 years after her initial presentation to the treating facility.

PubMed CentralRead more →

Triple-Negative Breast Cancer: Jacqueline's Patient Story

Patient Info: Jacqueline Bennett, Female, Under 40

Biomarkers: Initial ER-negative, PR-negative, HER2-negative; later HER2-positive

Jacqueline completed treatment for initial Stage IA triple-negative breast cancer during pregnancy and later developed a HER2-positive, hormone receptor-negative breast cancer. After 3 of 6 current treatments, the tumor was no longer visible on ultrasound or MRI, with targeted therapy and double mastectomy still planned.

The Patient StoryRead more →

Invasive Lobular Carcinoma: Louise's Survivor Story

Patient Info: Louise Butcher, Female

As of February 2026, Louise Butcher was living after lobular breast cancer, raising awareness about going flat, body image, and running after bilateral mastectomy.

Non-metastatic metaplastic triple-negative breast cancer with residual disease after chemotherapy

Patient Info: Anonymized, Female, 40s

Biomarkers: Metaplastic triple-negative breast cancer; HER2 0

The patient had an initial partial response to neoadjuvant chemotherapy but then progressed before surgery. Modified radical mastectomy found substantial residual metaplastic carcinoma with 0/21 nodes involved, followed by adjuvant radiotherapy and metronomic capecitabine.

PubMed CentralRead more →

Stage II HR-Positive Invasive Ductal Carcinoma: Janet's Patient Story

Patient Info: Janet Ayala, Female, Under 40 | Stage II

Biomarkers: ER-positive; PR-positive; HER2-positive; ATM mutation

After complete pathologic response and completion of HER2-targeted infusions, Janet remained in survivorship-focused ongoing care with estrogen suppression and additional endocrine/targeted therapy planning to reduce recurrence risk.

City of HopeRead more →