Breast cancer treated separately from concurrent diffuse large B-cell lymphoma

This breast cancer diagnosis at a glance

Subtype
Invasive Ductal Carcinoma
Biomarkers
ER-positive; PR-positive; HER2-positive
Sex
Female
Treatment
surgery

Treatment course, step by step

  1. After treatment was prioritized for her separate lymphoma, she underwent left mastectomy for the breast cancer in October 2022.

What happened, in summary

A 54-year-old woman noticed a painless enlarging mass in her neck. Imaging showed an abnormal area in the left breast together with enlarged lymph nodes in several parts of the body. At first, the widespread lymph-node disease looked like metastatic breast cancer.

Biopsies showed that she actually had two separate cancers. The breast lesion was invasive ductal carcinoma that was ER-positive, PR-positive, and HER2-positive. The enlarged lymph nodes were caused by diffuse large B-cell lymphoma rather than spread of the breast cancer.

Because the lymphoma was the more urgent disease, treatment initially focused on the lymphoma. After completing the first phase of lymphoma treatment, she underwent a left mastectomy in October 2022. Pathology confirmed an approximately 2 cm invasive ductal breast tumor.

Follow-up showed no local recurrence of the breast cancer. Her lymphoma later relapsed and required several additional treatments, while follow-up continued to show no local recurrence of the breast cancer.

Where this story comes from

This is a lay summary of an account first published by PMC / PubMed Central. Read the original in full

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