Stage IV Breast Cancer: Sherri's Patient Story

Patient Info: Sherri, Female | Stage IV

Biomarkers: BRCA1-negative

Metastatic Site: Bone marrow

As of November 2023, Sherri had no evidence of disease on recent breast cancer scans but remained on targeted treatment every 3 weeks and had started oxaliplatin after surgery for a separate Stage III colon cancer.

The Patient StoryRead more →

Stage IV HER2-Positive Multiple primaries: metastatic Breast Cancer + Colon/Colorectal Cancer: Sherri's Patient Story

Patient Info: Sherri, Female | Stage IV

Biomarkers: HER2-positive breast cancer; colon cancer Signatera positive before surgery and negative after surgery

Metastatic Site: Bone marrow

As of October 2023, Sherri had no evidence of disease on recent scans for HER2-positive metastatic breast cancer but was receiving oxaliplatin/Oxyplatin chemotherapy and transfusions for a separate early Stage III colon cancer.

The Patient StoryRead more →

Stage III Colorectal Cancer: Jessica's Patient Story

Patient Info: Jessica Bishop | Stage III

Jessica was receiving chemotherapy for Stage III colorectal cancer and had completed 2 of 4 planned rounds.

Fight Colorectal CancerRead more →

Breast cancer lung metastasis treated with a minimally invasive freezing procedure

Patient Info: Anonymized, Female | Stage IV

Biomarkers: HER2-positive; ER-negative

Metastatic Site: lungs

Follow-up PET/CT at 3, 6, 9 and 12 months after cryoablation showed no progression or new lesions without systemic therapy.

PubMed CentralRead more →

Nutritional recovery years after total gastrectomy for gastric cancer

Patient Info: Anonymized, male, 50s

He was alive 6 years after gastrectomy. PET in 2018 showed no recurrence, and CT in 2019 found no abdominal pathological changes while his later care focused on nutritional recovery.

PubMed CentralRead more →

Stage II MSI-High Colorectal Cancer: Shannon's Survivor Story

Patient Info: Shannon, Female, Under 40 | Stage II

Biomarkers: MSI-H; Lynch syndrome; MLH1 mutation

As of October 2023, Shannon had no recurrence described while approaching year 5 after Stage IIA colon cancer surgery and continued intensive Lynch syndrome surveillance.

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Invasive Lobular Carcinoma: Brenda's Survivor Story

Patient Info: Brenda, Female, 40s

Brenda completed mastectomy, chemotherapy, radiation and an oophorectomy. She remained on anastrozole and a CDK4/6 inhibitor when she shared her story.

Lobular Breast Cancer AllianceRead more →

Large Gastric Carcinosarcoma Removed With Partial Stomach Surgery

Patient Info: Anonymized, Female

Biomarkers: Pancytokeratin positive; CK7 positive; vimentin positive; DOG-1 negative; CD117 negative; calretinin negative; SMA negative; S100 negative

She recovered without postoperative complications and remained asymptomatic for 3 months. At 6 months, she died after intensive-care admission for a lower urinary tract infection and urosepsis.

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Stage IV HER2-Positive Inflammatory Breast Cancer: Olivia's Survivor Story

Patient Info: Olivia Franz, Female, Under 40 | Stage IV

Biomarkers: HER2-positive

Metastatic Site: Bones; distant lymph nodes

As of October 2023, Olivia continued to show no evidence of disease on scans while receiving maintenance trastuzumab and pertuzumab every 3 weeks and zoledronic acid every 3 months for bone health.

MD AndersonRead more →

Stage IV Colorectal Cancer: Julie's Patient Story

Patient Info: Julie Flower, Female | Stage IV

Metastatic Site: Liver; lungs; lymph nodes; bones

As of September 2023, Julie had longstanding Stage IV colorectal cancer but a strong clinical-trial response after about 2.5 years on trial, with possible first no-evidence-of-disease assessment expected soon but not confirmed in this record.

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Early-stage breast cancer (DCIS) found unexpectedly within a benign breast lump

Patient Info: Anonymized, Female

At 6 months she was asymptomatic with no palpable breast or axillary masses and entered annual MRI surveillance.

PubMed CentralRead more →

BRCA2-Mutated Metastatic Lung Adenocarcinoma Controlled for 30 Months With Olaparib

Patient Info: Anonymized, female, 60s | Stage IV

Biomarkers: PD-L1-negative; BRCA2 mutation; ATM mutation; EGFR-negative; ALK-negative

Metastatic Site: brain

Olaparib provided about 30 months of disease control, and PET imaging remained overall stable when a separate new breast primary was found in February 2023.

PubMed CentralRead more →

New Triple-Negative Breast Cancer Develops During Olaparib Treatment for a Separate Lung Cancer

Patient Info: Anonymized, female, 60s

Biomarkers: Triple-negative; germline BRCA2 mutation; BRCA2 reversion mutation

A woman receiving olaparib for BRCA2-mutated metastatic lung cancer developed a separate 14 mm triple-negative breast cancer with a BRCA2 reversion mutation.

PubMed CentralRead more →

Stage III Colorectal Cancer: Amanda's Survivor Story

Patient Info: Amanda Peters, Female, 40s | Stage III

Biomarkers: No genetic markers reported

As of September 2023, Amanda reported no recurrence about 3 years after Stage IIIB rectal cancer surgery and adjuvant chemotherapy, with surveillance CT scans now yearly.

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Invasive Lobular Carcinoma: Leigh's Patient Story

Patient Info: Leigh, Female

Leigh died in June 2022 from complications of ovarian cancer. Her lobular breast cancer experience led her to co-found the Lobular Breast Cancer Alliance and build a lasting patient-advocacy legacy.

Lobular Breast Cancer AllianceRead more →

Stage IV Colorectal Cancer: Keith's Patient Story

Patient Info: Keith, Male, 40s | Stage IV

Metastatic Site: Liver; lymph nodes; lungs

As of September 2023, Keith was on third-line treatment for Stage IV colon cancer with lung metastases, small lung lesions under 1 cm, a low tumor marker after 2 rounds, and possible trial/transplant options after standard care.

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Rare blood-vessel-based lung tumor (epithelioid hemangioendothelioma)

Patient Info: Anonymized, Female

Biomarkers: PEH positive for CD31, ERF and TFE3

At 1-year CT follow-up, residual pulmonary nodules were stable and there were no distant metastases.

PubMed CentralRead more →

Stage IV Triple-Negative Breast Cancer: April's Patient Story

Patient Info: April Donaldson, Female, 40s | Stage IV

Biomarkers: Triple-negative breast cancer; BRCA1 positive

Metastatic Site: Lungs

As of September 2023, April was living with Stage IV metastatic triple-negative breast cancer in the lungs; scans were stable in February but showed growth again in July, and PARP inhibitor therapy was being planned.

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Stage IV Ovarian Cancer: Melbey's Patient Story

Patient Info: Melbey Segovia, Female | Stage IV

Melbey Segovia died on May 4, 2021, about 5 years and 3 months after her February 2016 diagnosis, after three relapses and hospice care.

Dana-FarberRead more →

Hidden colon cancer first discovered through a rare brain/nerve inflammation

Patient Info: Anonymized, Male | Stage II

At 1 year he was asymptomatic and off treatment, with no neurological deficits and a normal repeat PET scan.

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Cancer Researcher Becomes Cancer Survivor

Patient Info: J. Mark Brown, Male | Stage III

Ten years after his Stage III colorectal cancer diagnosis, Mark described the treatment as having cured his cancer; he had completed 6 years of periodic oncology follow-up and was living actively with an ileostomy.

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Stage IV HER2-Positive Colorectal Cancer: Brian's Patient Story

Patient Info: Brian Beck, 50s | Stage IV

Biomarkers: HER2-positive

Metastatic Site: liver

Brian was receiving tucatinib plus trastuzumab on a clinical trial and was working full time 4.5 years after his Stage IV diagnosis.

Stage III Ovarian Cancer: Jaclyn's Patient Story

Patient Info: Jaclyn (Jackie) VanRaaphorst | Stage III

Biomarkers: FRα-positive; CA-125 monitored

AACR later reported that Jackie died on January 16, 2025.

Stage IV Colorectal Cancer: Danielle's Patient Story

Patient Info: Danielle Archer, Female, 40s | Stage IV

Biomarkers: No genetic markers reported

Metastatic Site: Liver; lungs

As of August 2023, Danielle was living with Stage IV metastatic colon cancer involving liver and lung lesions that were stable on ongoing treatment and 3-month surveillance scans.

The Patient StoryRead more →