Silicone lymphadenopathy after treatment for recurrent triple-negative breast cancer

Patient Info: Anonymized, Female, 50s

Biomarkers: Triple-negative; BRCA1-negative; BRCA2-negative; latest recurrence Ki-67 60%–70%.

At the May 2020 follow-up, biopsies confirmed silicone-related lymph-node changes rather than cancer, and imaging showed no recurrent disease while six-monthly surveillance continued.

PubMed CentralRead more →

Rectal cancer that later spread to the vagina

Patient Info: Anonymized, Female, 60s | Stage IV

Metastatic Site: vagina

The isolated vaginal metastasis was surgically removed and followed by another 12 cycles of chemotherapy.

PubMed CentralRead more →

A difficult breast-reconstruction infection after breast cancer treatment

Patient Info: Anonymized, Female, 40s

After wide debridement and prolonged antibiotic treatment, the breast and abdominal wounds healed, imaging showed resolution of the subcutaneous infection, and no infection recurrence was seen over three years.

PubMed CentralRead more →

Lung cancer remission after pembrolizumab despite severe inflammatory arthritis

Patient Info: Anonymized, Male, 50s | Stage Metastatic/Advanced

Biomarkers: PD-L1-positive.

Metastatic Site: brain (temporal and parietal lobes)

The lung adenocarcinoma remained in complete remission 28 months after diagnosis, while the treatment-related arthritis also reached sustained remission and he returned to work and exercise.

PubMed CentralRead more →

Extensive-stage small cell lung cancer with acquired haemophilia

Patient Info: Anonymized, Female, 60s

Biomarkers: Synaptophysin weakly positive; Ki-67 greater than 90%.

Her small cell lung cancer remained stable on imaging one month before her death, which followed aseptic meningitis after intravenous immunoglobulin treatment for autoimmune myasthenia gravis.

PubMed CentralRead more →

Ductal and lobular carcinoma in situ arising within a fibroadenoma

Patient Info: Anonymized, Female, 40s

Biomarkers: DCIS ER-positive and PR-positive; LCIS E-cadherin-negative.

Lumpectomy achieved tumor-free margins for the in situ disease, and she subsequently completed adjuvant radiation therapy.

PubMed CentralRead more →

Locally advanced male breast cancer associated with a pathogenic ATM variant

Patient Info: Anonymized, Male, 50s | Stage Metastatic/Advanced

Biomarkers: ER 100% positive; PR 100% positive; HER2-negative; Ki-67 30%; germline pathogenic ATM variant c.2921+1G>A.

Two years after diagnosis, he had an ECOG performance status of 0 and remained without signs of breast-cancer relapse or another primary cancer.

PubMed CentralRead more →

A durable response to trastuzumab in heavily pretreated metastatic breast cancer

Patient Info: Anonymized, Female, 60s | Stage IV

Biomarkers: Initial tumor ER-positive and PR-positive. Metastatic liver biopsy ER-negative and PR-negative with HER2 IHC 1+ and nonamplified. Later biopsy ER and PR weakly positive at 5%–10%, HER2 IHC 1+ and nonamplified, and ERBB3 p. with evidence of HER2/HER3 pathway activation.

Metastatic Site: lungs; hilar and mediastinal lymph nodes; liver; bone

She had ongoing benefit for more than 10 months on trastuzumab and capecitabine, with improved symptoms, lower tumor markers, and a confirmed partial response.

PubMed CentralRead more →

Emergency Repair of a Long-Term Perineal Hernia After Rectal Cancer Surgery

Patient Info: Anonymized, Female, 70+ | Stage IV

Metastatic Site: lungs

She lived with metastatic rectal cancer and received community palliative care after becoming too frail for further chemotherapy.

PubMed CentralRead more →

Stage I Breast Cancer: Melissa's Patient Story

Patient Info: Melissa | Stage I

Melissa was in remission and continued hormone therapy while managing fear of recurrence.

Our Cancer StoriesRead more →

Ana's Stage 2 Breast Cancer and Cancer-Free Milestone

Patient Info: Ana, Female, 50s | Stage II

Ana completed intensive multimodal treatment and was declared cancer-free in 2024. She continued Tamoxifen as a planned 5-year hormone-therapy course.

Our Cancer StoriesRead more →

Stage II Breast Cancer: Ingrid's Patient Story

Patient Info: Ingrid | Stage II

Ingrid said her stage 2 breast cancer was in remission while she continued a low-toxicity systemic anticancer monotherapy.

Our Cancer StoriesRead more →

Stage II Colorectal Cancer: Chad's Patient Story

Patient Info: Chad | Stage II

Chad was recovering from radiation and preparing for major colorectal surgery while managing anxiety about treatment and its effects.

Our Cancer StoriesRead more →

Stage III Colorectal Cancer: Cleo's Survivor Story

Patient Info: Cleo | Stage III

Cleo completed active treatment and reports that she is in remission more than 3 years after her February 2021 diagnosis.

Our Cancer StoriesRead more →

NRG1-Fusion Lung Cancer With a 24-Month Response to Afatinib

Patient Info: Anonymized, Female, 50s | Stage Metastatic/Advanced

Biomarkers: NRG1 fusion; KRAS/EGFR/ALK/ROS1/ERBB2 alterations not detected

Metastatic Site: left lung

Her cancer progressed during atezolizumab, and she died in May 2019.

PubMed CentralRead more →

Nearly 5 years without rectal cancer recurrence when a lung nodule proved to be infection

Patient Info: Anonymized, Male, 60s

He remained without rectal-cancer recurrence for nearly 5 years after diagnosis. A new lung nodule found in 2020 was surgically biopsied and proved to be Pneumocystis infection rather than metastasis or a new lung cancer.

PubMed CentralRead more →

Stage IV Mucinous Lung Cancer Treated With Afatinib and Surgery

Patient Info: Anonymized, Female, 40s | Stage IV

Biomarkers: CD74-NRG1 fusion; ALK/ROS1/EGFR/BRAF/KRAS/MET/HER2 wild type; PD-L1 initially not expressed and later 0%-20%

Metastatic Site: bilateral lungs|bone|right adrenal gland

She was alive and receiving treatment after bone and right-adrenal progression at the latest follow-up.

PubMed CentralRead more →

Cherie's Stage 2 Breast Cancer Story After a Second Opinion

Patient Info: Cherie, Female, 50s | Stage II

Cherie described herself as being in remission while continuing hormone therapy. She remained concerned about relapse and used travel and painting to manage anxiety.

Our Cancer StoriesRead more →

Stage III Breast Cancer: Onagh's Survivor Story

Patient Info: Onagh, Female | Stage III

Her stage 3 breast cancer was in complete remission, and she no longer required treatment.

Our Cancer StoriesRead more →

Metastatic Right-Sided Colon Cancer With an NRG1 Fusion

Patient Info: Anonymized, Male, 60s | Stage IV

Biomarkers: KRAS mutation; POMK-NRG1 fusion

Metastatic Site: liver|lungs

He had persistent metastatic disease after 16 months of afatinib and entered a phase I trial in January 2020.

PubMed CentralRead more →

Stage IV Breast Cancer: Harper's Patient Story

Patient Info: Harper, Female, 50s | Stage IV

Harper was living with Stage IV breast cancer after self-funded private treatment that included mastectomy, lymphadenectomy, chemotherapy, and radiation therapy; she felt better than before diagnosis but still hoped for complete recovery.

Our Cancer StoriesRead more →

Stage III Breast Cancer: Aurora's Patient Story

Patient Info: Aurora, Female, 40s | Stage III

Aurora was treated for Stage III breast cancer with mastectomy, lymphadenectomy, Cytoxan chemotherapy, and radiation therapy, then moved to chemotherapy alone after the initial plan was not working effectively.

Our Cancer StoriesRead more →

Breast Cancer: Maria's Patient Story

Patient Info: Maria

Maria underwent mastectomy, lymph-node surgery, chemotherapy, and radiation and continued to work through fear that the treatment might not succeed.

Our Cancer StoriesRead more →

Stage IV Breast Cancer: Rachael's Patient Story

Patient Info: Rachael | Stage IV

Rachael was living with stage 4 breast cancer after following a plan of mastectomy, chemotherapy, and radiation therapy.

Our Cancer StoriesRead more →