Radiation: 1,109 Real Stories

1,109 stories match radiation. 868 of them mention chemotherapy.

Cancer Stories

A patient, who was diagnosed with Stage IV Lung AdenocarcinomaLung Cancer

Stage IV Lung Adenocarcinoma Presenting as Persistent Chest Pain and Rib Metastasis

Patient Info: Anonymized, male, 60s | Stage IV

Biomarkers: TP53 mutation; PD-L1 30%; no sensitive driver mutation identified

Metastatic Site: bone

After delayed diagnosis of Stage IV lung adenocarcinoma with a painful rib metastasis, he began systemic immunotherapy and local treatment for the painful bone lesion.

PubMed Central
OutcomeCare Ongoing
MT
Breast Cancer

Metaplastic triple-negative breast cancer: near-complete response to taxane/carboplatin before surgery

Patient Info: Anonymized, Female, Under 40 | Stage Metastatic/Advanced

Biomarkers: ER-negative; PR-negative; HER2-negative; CA 15-3 elevated, triple negative

As of April 2025, imaging after taxane/carboplatin showed a near-complete morpho-metabolic response in the right breast and major reduction of axillary nodal disease, followed by surgery and adjuvant chemotherapy/radiotherapy.

PubMed Central
OutcomeResponding Well
A patient, who was diagnosed with Stage IV Non-Small Cell Lung CancerLung Cancer

Metastatic SMARCA4-Deficient Lung Cancer Controlled for More Than Two Years With Tislelizumab and Fruquintinib

Patient Info: Anonymized, male, 60s | Stage IV

Biomarkers: PD-L1 8%; no target-sensitive mutation identified

Metastatic Site: left adrenal gland, cervical lymph nodes

After radiotherapy reduced the cervical-node metastasis, imaging on April 26, 2024 showed stable disease. He ended trial treatment after 2 years and continued regular follow-up.

PubMed Central
OutcomeStable Disease
A patient, who was diagnosed with Stage II Breast CancerBreast Cancer

HER2-amplified primary mucinous cystadenocarcinoma of the breast: surgery and adjuvant treatment

Patient Info: Anonymized, Female, 60s | Stage II

Biomarkers: HER2-amplified / HER2 3+; ER/PR-negative; Ki-67 ~50%; p53 high; microsatellite stable. No clinically significant inherited mutation reported.

As of November 2024, she had more than 104 months of disease-free survival after breast-conserving surgery, sentinel lymph node biopsy, EC-T chemotherapy, and radiotherapy for Stage IIA HER2-amplified primary mucinous cystadenocarcinoma of the breast.

PubMed Central
OutcomeCancer-Free / NED
A patient, who was diagnosed with Invasive Ductal CarcinomaBreast Cancer

Lung inflammation from pembrolizumab immunotherapy returned months after stopping treatment

Patient Info: Anonymized, Female, 70+

Biomarkers: Estrogen receptor-negative; progesterone receptor-negative; HER2-negative

Surgery confirmed a pathologic complete response, and she remained in breast-cancer remission during routine follow-up after treatment for recurrent pembrolizumab-related pneumonitis.

PubMed Central
OutcomeCancer-Free / NED
A patient, who was diagnosed with Stage IV Lung AdenocarcinomaLung Cancer

Stage 4 ALK-rearranged lung cancer: complete response with alectinib and SBRT

Patient Info: Anonymized, Female, 70+ | Stage IV

Biomarkers: Initial tumor: EML4-ALK fusion, EGFR wild type. Later tumor: EGFR L858R/T790M and TP53 L194R, without ALK rearrangement.

Metastatic Site: pleura, lymph nodes

As of March 2025, the original ALK-rearranged metastatic disease had responded to alectinib, the separate EGFR-mutant right upper-lobe lesion had responded to SBRT, and PET-CT showed no hypermetabolic lung lesion.

PubMed Central
OutcomeCancer-Free / NED
A patient, who was diagnosed with Stage IV Non-Small Cell Lung CancerLung Cancer

Stage 4 SMARCA4-deficient lung cancer: ongoing treatment response

Patient Info: Anonymized, Male, 50s | Stage IV

Biomarkers: SMARCA4-deficient lung cancer with BRG-1 loss, CK/CK7 positive, Ki-67 >40%. CEA

Metastatic Site: sigmoid colon, left adrenal gland

After colon metastasis surgery, continued radiotherapy, and later gemcitabine/nedaplatin/bevacizumab/camrelizumab for adrenal metastasis, the cancer showed a favorable response with no further recurrence or new metastasis reported.

PubMed Central
OutcomeResponding Well
A patient, who was diagnosed with Stage IV Invasive Ductal CarcinomaBreast Cancer

HER2-positive breast cancer with brain metastases: responding well to T-DXd

Patient Info: Anonymized, Female, 50s | Stage IV

Biomarkers: ER-positive; PR-positive; HER2-positive / HER2 IHC 3+

Metastatic Site: brain (left cerebellum, left frontal lobe, medulla)

After 14 months and 19 doses of T-DXd, brain metastases remained controlled with no symptomatic or radiological relapse and no severe T-DXd-related adverse events.

PubMed Central
OutcomeResponding Well
A patient, who was diagnosed with Stage III Inflammatory Breast CancerBreast Cancer

Bilateral inflammatory breast cancer treated with pembrolizumab and surgery

Patient Info: Anonymized, Female, 40s | Stage III

Biomarkers: Bilateral breast cancers had different biology: right side ER/PR-positive and HER2 FISH-negative; left side triple-negative/HER2 1+.

As of March 2025, she had no recurrence 6 months after bilateral mastectomy, bilateral axillary lymph node dissection, thoracoabdominal flap closure, and planned postmastectomy radiation for Stage IIIC bilateral inflammatory breast cancer.

PubMed Central
OutcomeCancer-Free / NED
Heather, who was diagnosed with Stage III Colorectal CancerColorectal Cancer

Stage III Colorectal Cancer: Heather's Survivor Story

Patient Info: Heather Russell, Female, Under 40 | Stage III

In her fifth year of remission at the time of the 2025 story after treatment for Stage III rectal cancer; she had returned to family and working life, with some lasting treatment effects.

Cleveland Clinic
OutcomeCancer-Free / NED
Courtney, who was diagnosed with Stage III Colorectal CancerColorectal Cancer

Stage III Colorectal Cancer: Courtney's Survivor Story

Patient Info: Courtney Vigars, Female, Under 40 | Stage III

In her fifth year of remission at the time of the 2025 story after transanal surgery, radiation, and chemotherapy for Stage III rectal cancer; she had returned to an active working life.

Cleveland Clinic
OutcomeCancer-Free / NED
Bill, who was diagnosed with Stage IV Colorectal CancerColorectal Cancer

Stage IV Colorectal Cancer: Bill's Patient Story

Patient Info: Bill, Male, 40s | Stage IV

Metastatic Site: Liver | Lungs | Brain

As of March 2025, Bill was living with incurable Stage IV colon cancer after liver, lung, and brain involvement, with ongoing chemotherapy and lifelong maintenance treatment.

The Patient Story
OutcomeLiving With Cancer
A patient, who was diagnosed with Stage IV Lung AdenocarcinomaLung Cancer

Metastatic lung adenocarcinoma: complete remission on nivolumab complicated by immune-mediated diabetes

Patient Info: Anonymized, Male, 50s | Stage IV

Biomarkers: Lung tumor: EGFR wild type, ALK rearrangement not detected. Immune-mediated diabetes: islet/GAD antibodies negative and C-peptide undetectable.

Metastatic Site: brain (cerebellum and occipital lobe); liver

As of March 2025, serial CT and MRI scans through October 2023 showed no evidence of oncologic disease after nivolumab, while immune-mediated diabetes was controlled with basal-bolus insulin.

PubMed Central
OutcomeCancer-Free / NED
Bill, who was diagnosed with Stage IV Colorectal CancerColorectal Cancer

Stage IV KRAS Colorectal Cancer: Bill's Patient Story

Patient Info: Bill, Male, 40s | Stage IV

Biomarkers: KRAS mutation

Metastatic Site: liver; lung; brain

Bill has Stage IV KRAS G12A-mutated colon cancer with liver, lung, and brain metastases. After multiple surgeries, ablation, Gamma Knife, and repeated chemotherapy, tumors shrank and he moved to lifelong maintenance chemotherapy every 2 weeks as of March 2025.

The Patient Story
OutcomeLiving With Cancer
Rosemary, who was diagnosed with Stage IV Lung CancerLung Cancer

Stage IV KRAS Lung Cancer: Rosemary's Patient Story

Patient Info: Rosemary Conway, female, 60s | Stage IV

Biomarkers: KRAS mutation

After 14 months on daraxonracib in a clinical trial, Rosemary’s Stage IV lung cancer had stopped growing and she had returned to walking and lifting weights.

Dana-Farber
OutcomeStable Disease