osimertinib: 29 Real Stories
29 stories match osimertinib. 11 of them mention surgery.
T790M-negative lung cancer on afatinib after AZD9291 trial ineligibility
This Noxte entry followed a disappointing oncology update on 19 April. The patient learned that the blood sample sent to the laboratory was negative for T790M resistance, so he could not enter the AZD9291/osimertinib clinical trial. He found that frustrating…
Read this storyLung cancer on afatinib after liquid biopsy showed T790M resistance no longer detected
This Noxte post explained how liquid biopsy was beginning to affect the patient’s lung cancer care. He had been participating in blood-based monitoring to track treatment effects and possible resistance. At an oncology visit, his doctors had the latest blood…
Read this storyLung cancer with acquired T790M resistance: erlotinib switched to afatinib while AZD9291/TAGRISSO trial was considered
By January 2016, this Spanish lung cancer blogger was marking 2 years of survival while facing a new treatment setback. Recent bronchoscopy and blood testing confirmed that the cancer had developed resistance, including the T790M mutation. That finding…
Read this storyLung cancer progression on Tarceva with urgent T790M resistance testing planned
In January 2016, this lung cancer patient learned that a recent CT scan explained his worsening cough. The scan showed clear progression: the right upper-lobe mass had grown to about 4.9 x 5 cm, with extension to the visceral pleura, involvement around the…
Read this storyEGFR-mutated NSCLC on Tarceva with CT follow-up pending and future resistance options discussed
In December 2015, this patient was living with EGFR-mutated non-small cell lung cancer and taking Tarceva, also called erlotinib, which he had started in January. Much of this post reflected his effort to understand the fast-changing treatment landscape. He…
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