Right Stage IIB ER/PR-positive breast cancer with left epithelioid MPNST: no recurrence after surgery

Patient Info: Anonymized, Female, 70+ | Stage II

Biomarkers: Right breast cancer was ER/PR-positive, HER2-negative/1+

As of March 2025, 3 years after bilateral mastectomy, there was no recurrence of the right breast cancer or the left epithelioid malignant peripheral nerve sheath tumor; she remained on anastrozole for the right breast cancer.

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Left breast epithelioid MPNST with concurrent right breast cancer: no recurrence after surgery

Patient Info: Anonymized, Female, 70+ | Stage III

Biomarkers: Left MPNST markers included S100 and SOX10 positivity. Right breast cancer was ER/PR-positive, HER2-negative/1+

As of March 2025, 3 years after bilateral mastectomy, there was no recurrence of the left epithelioid MPNST or the concurrent right breast invasive ductal carcinoma.

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Breast Cancer: Erica's Survivor Story

Patient Info: Erica Deligne, Female

As of March 2025, Erica Deligne was a breast cancer survivor and style advocate helping people understand aesthetic flat closure and post-surgery confidence.

Invasive Lobular Carcinoma: Claudia's Survivor Story

Patient Info: Claudia, Female, 40s

Biomarkers: Grade 3

As of March 2025, Claudia described herself as a breast cancer survivor and advocate after mastectomy for multifocal grade 3 ILC, with whole-person healing and community support central to recovery.

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Synchronous breast and right colon cancers: response to carboplatin-paclitaxel and surgery

Patient Info: Anonymized, Female, 70+

Biomarkers: Breast cancer was ER/PR positive, HER2 negative

As of March 2025, 9-month follow-up showed no local recurrence or distant metastasis after multimodal treatment, while she continued anastrozole.

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Stage II Triple-Negative Breast Cancer With Severe Myelitis During Pembrolizumab Treatment

Patient Info: Anonymized, Female, 60s | Stage II

Biomarkers: ER-negative, PR-negative, HER2-negative, germline PALB2 variation

Imaging showed a complete tumor response before surgery, and surgery 6 months later found no residual breast cancer or involved sentinel nodes.

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Stage III HR-Positive Invasive Lobular Carcinoma: Katie's Patient Story

Patient Info: Katie, Female, Under 40 | Stage III

Biomarkers: ER-positive; PR-positive; HER2-negative; genetic testing negative

As of February 2025, Katie was a few months beyond active treatment for Stage III ER-positive, PR-positive, HER2-negative ILC and was adjusting to maintenance therapy with Verzenio, Lupron, and Letrozole.

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Facing Triple-Negative Breast Cancer: Chance’s Story

Patient Info: Chance, Female, Under 40 | Stage II

Biomarkers: ER-negative; PR-negative; HER2-negative; BRCA1 mutation

As of February 2025, Chance described follow-up after Stage II BRCA1-associated triple-negative breast cancer and stated that she did not currently have cancer, while continuing close surveillance.

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Stage III Triple-Negative Breast Cancer: Kelly's Survivor Story

Patient Info: Kelly, Female, Under 40 | Stage III

Biomarkers: Triple-negative breast cancer; no inherited cancer gene mutation found.

As of February 2025, Kelly identified as a Stage IIIC triple-negative breast cancer survivor after neoadjuvant chemotherapy, double mastectomy with reconstruction, and radiation, and was using her experience to support others through TNBC Thrivers.

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Metastatic Breast Cancer Returning About 20 Years After Initial Treatment

Patient Info: Anonymized, Female | Stage IV

Biomarkers: ER-positive, PR-negative, HER2-positive

Metastatic Site: bones

About 20 years after her original breast-cancer treatment and sustained remission, bone biopsy confirmed metastatic recurrence; she became too unwell for planned cancer therapy and chose supportive care.

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Breast cancer survivor with synchronous intercostal nerve schwannomas mimicking metastasis

Patient Info: Anonymized, Female, Under 40

Biomarkers: Breast cancer biomarkers not reported; schwannomas were S100-positive

After prior breast cancer treatment, later D6-D7/rib lesions were proven to be S100-positive schwannomas rather than metastases, and surgical removal relieved the patient’s rib-cage numbness and pain.

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Stage 4 hormone receptor-positive breast cancer: remission with PARP inhibitor

Patient Info: Anonymized, Female, 40s | Stage IV

Biomarkers: HR-positive breast cancer with HER2-low/negative recurrence, and pathogenic BRCA2 R2318* mutation.

Metastatic Site: pleura

As of January 2025, she had maintained complete response for 36 months after sequential FEC/docetaxel and olaparib for hormone receptor-positive, HER2-negative/HER2-low metastatic breast cancer with BRCA2 R2318* mutation.

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Breast Cancer Recurring Years Later With Leptomeningeal Spread and a Brief Response to Trastuzumab Deruxtecan

Patient Info: Anonymized, Female, 60s | Stage IV

Biomarkers: ER-positive, PR-positive, HER2-low

Metastatic Site: peritoneum, retroperitoneum, bones, leptomeninges

Died on May 10, 2024, about 18 years after her April 2006 breast-cancer diagnosis and about 6 years after metastatic recurrence.

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Stage 3B breast cancer: partial mastectomy with pulmonary complications

Patient Info: Anonymized, Female, 70+ | Stage III

Partial mastectomy was completed for local control of bleeding/anemia in Stage IIIB breast cancer; she was discharged on postoperative day 7 without complications, but long-term cancer control was not reported.

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Stage II HR-Positive Invasive Lobular Carcinoma: Karen's Survivor Story

Patient Info: Karen, Female, 40s | Stage II

Biomarkers: ER-positive; PR-positive; HER2-negative; grade 2; inherited genetic testing negative

Karen completed double mastectomy, 3 months of chemotherapy and reconstruction. She was doing well on ongoing endocrine and targeted therapy and walking 3–5 miles daily.

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Breast Cancer Followed by a Separate Pleural Mesothelioma

Patient Info: Anonymized, Female, 40s

Follow-up imaging after breast-cancer treatment showed no regrowth before a separate pleural mesothelioma was diagnosed.

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Stage I ER-positive/HER2-positive breast cancer with radiation-associated morphea

Patient Info: Anonymized, Female, 70+ | Stage I

Biomarkers: ER-positive; PR-negative; HER2-positive

No evidence of breast cancer recurrence after 2018 treatment; ongoing issue was generalized morphea and breast deformity related to prior radiation, improved with mycophenolate by April 2024.

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Stage I Triple-Negative Adenoid Cystic Carcinoma of the Breast

Patient Info: Anonymized, Female, 50s | Stage I

Biomarkers: Triple-negative

At 6-month follow-up, imaging showed no recurrence or new cancer-related complications.

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Stage IV Breast Cancer: Kate's Patient Story

Patient Info: Kate, Female, Under 40 | Stage IV

Biomarkers: Hormone-positive

Metastatic Site: Hip bone; lymph nodes near the lungs

Kate remained in active chemotherapy for stage IV disease, with surgery and radiation planned.

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Stage IV HR-Positive Breast Cancer: Kate's Patient Story

Patient Info: Kate, Female, Under 40 | Stage IV

Biomarkers: HR-positive

Metastatic Site: lymph nodes near the lungs; chest wall and skin…

Kate was receiving chemotherapy for Stage IV hormone-positive breast cancer, with surgery and radiation discussed as planned next steps but not yet completed in the source.

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Two sisters with invasive lobular breast cancer and a shared CDH1 mutation

Patient Info: Anonymized, Female | Stage Metastatic/Advanced

Biomarkers: Both sisters had pathogenic CDH1 p.. Breast cancers were HER2-negative; older sister also had a PTCH1 variant of uncertain significance.

As of January 2025, both sisters were under ongoing hereditary diffuse gastric cancer surveillance with annual EGD after breast cancer treatment; no signs of HDGC or metastatic breast cancer were reported.

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Stage III Breast Cancer Complicated by a Large Liver Abscess

Patient Info: Anonymized, Female, 70+ | Stage III

Biomarkers: ER-positive, HER2-negative

Continuing adjuvant anastrozole and oncology follow-up after mastectomy for Stage III breast cancer.

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Stage IIIA encapsulated papillary breast carcinoma with invasion: mastectomy, axillary dissection, and anastrozole

Patient Info: Anonymized, Female, 70+ | Stage III

Biomarkers: ER 100%; PgR 80%; HER2 2+ by IHC with FISH negative; Ki-67 20%; initial biopsy HER2 1+

She received postoperative anastrozole alone after right mastectomy and axillary dissection; no apparent recurrence was observed 18 months after surgery.

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Stage I triple-negative solid basaloid adenoid cystic breast cancer treated with mastectomy and oral chemotherapy

Patient Info: Anonymized, Female, 70+ | Stage I

Biomarkers: Current tumor was triple-negative with high Ki-67 and c-kit/CK7 staining. Prior breast cancer was ER-positive, HER2-positive, PR-negative.

One year after mastectomy and postoperative tegafur-gimeracil-oteracil potassium, she was recovering well without signs of metastasis.

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