Genetic Testing: 25 Real Stories

25 stories match genetic testing. 24 of them mention surgery.

Susan, who was diagnosed with Stage I Invasive Ductal CarcinomaBreast Cancer

Stage I Invasive Ductal Carcinoma: Susan's Patient Story

Patient Info: Susan, Female | Stage I

Biomarkers: ER 100% positive; HER2-negative; progesterone receptor result not reported; multigene testing pending

Susan had completed breast surgery for a small early-stage invasive ductal cancer and was awaiting final pathology and genetic results to determine whether radiation, chemotherapy, and long-term endocrine therapy would be needed.

breastcancer.org
OutcomeCare Ongoing
Linnea, who was diagnosed with Stage IV Non-Small Cell Lung CancerLung Cancer

Stage IV ALK Non-Small Cell Lung Cancer: Linnea's Patient Story

Patient Info: Linnea Olson, Female, 40s | Stage IV

Biomarkers: ALK mutation / ALK-rearranged lung cancer

Metastatic Site: Lungs / intrapulmonary disease

Living long term with Stage IV ALK-positive NSCLC; ALK-targeted clinical trials controlled disease for years but were described as disease control rather than cure.

Massachusetts General Hospital
OutcomeLiving With Cancer
Jay, who was diagnosed with Stage IV Lung CancerLung Cancer

Stage IV ALK Lung Cancer: Jay's Survivor Story

Patient Info: Jay Petri, Male | Stage IV

Biomarkers: ALK mutation / ALK-rearranged lung cancer

Metastatic Site: Not reported

Stage IV ALK-positive lung cancer treated through clinical trials at Mass General; he reported being cancer-free for nearly 1.5 years after going through 3 trials.

Massachusetts General Hospital
OutcomeCancer-Free / NED
Kevin, who was diagnosed with Stage I Breast CancerBreast Cancer

Stage I Breast Cancer: Kevin's Patient Story

Patient Info: Kevin Jarvis, Male | Stage I

Biomarkers: Genetic testing inconclusive; receptor status not reported

Early male breast cancer treated with mastectomy, sentinel node biopsy, EC chemotherapy, paclitaxel/Taxol, and ongoing daily tamoxifen; latest source text describes good spirits and continued discussion of risk-reducing surgery, but does not explicitly state NED.

Cancer Council Australia
OutcomeCare Ongoing
Amber, who was diagnosed with Stage IV Colorectal CancerColorectal Cancer

Stage IV Colorectal Cancer: Amber's Survivor Story

Patient Info: Amber Madden, Female, 40s | Stage IV

Biomarkers: Comprehensive hereditary cancer genetic testing negative; tumor biomarkers not reported

Metastatic Site: Liver

Stage III colon cancer upstaged to Stage IV after liver metastasis was found; after colectomy, chemotherapy, liver surgery, and more chemotherapy, CT scans in May, August, and November 2025 showed no evidence of active cancer.

Fight Colorectal Cancer
OutcomeCancer-Free / NED
Rachel, who was diagnosed with Stage II Breast CancerBreast Cancer

Stage II BRCA2 Breast Cancer: Rachel's Patient Story

Patient Info: Rachel Zitofsky, Female, Under 40 | Stage II

Biomarkers: BRCA2 mutation

Rachel was doing well 4.5 years after Stage II breast cancer diagnosis and continued tamoxifen; her BRCA2 result also led her sister to expanded testing and preventive care.

Memorial Sloan Kettering
OutcomeCare Ongoing
Jackie, who was diagnosed with Stage IV Colorectal CancerColorectal Cancer

Stage IV Colorectal Cancer: Jackie's Patient Story

Patient Info: Jackie, Female | Stage IV

Biomarkers: Lynch syndrome

Metastatic Site: Not reported

Jackie’s Stage IIIB rectal cancer later recurred as Stage IV/metastatic disease, but early immunotherapy response was strong, with no visible tumor on MD Anderson sigmoid scope about 6 weeks after starting treatment.

The Patient Story
OutcomeResponding Well
Tommy, who was diagnosed with Stage III Colorectal CancerColorectal Cancer

Stage III MSI-High Colorectal Cancer: Tommy's Survivor Story

Patient Info: Tommy Allen, Male, 50s | Stage III

Biomarkers: MSI-high; Lynch syndrome

As of November 2025, Tommy was cancer-free 5 years after pembrolizumab, ileostomy, Whipple procedure, partial colectomy, and ileostomy closure for Stage III MSI-high colon cancer with Lynch syndrome.

MD Anderson
OutcomeCancer-Free / NED
Jennifer, who was diagnosed with Stage II Breast CancerBreast Cancer

Stage II Triple-Negative Breast Cancer: Jennifer's Survivor Story

Patient Info: Jennifer Rancik, Female, Under 40 | Stage II

Biomarkers: BRCA1 mutation; triple-negative breast cancer

Jennifer entered remission in October 2017 after Stage II triple-negative breast cancer treatment and, as of October 2025, reported doing great and being off medications except occasional Zometa.

City of Hope
OutcomeCancer-Free / NED
Sara, who was diagnosed with Breast CancerBreast Cancer

HR-Positive Breast Cancer: Sara's Patient Story

Patient Info: Sara Glenn, Female, Under 40

Biomarkers: TP53 mutation / Li-Fraumeni syndrome; ER-positive; HER2-negative

As of June 2025, Sara had completed bilateral mastectomy and reconstruction for ER-positive, HER2-negative breast cancer and was on planned 10-year tamoxifen plus intensive Li-Fraumeni syndrome surveillance for herself and her daughters.

City of Hope
OutcomeCare Ongoing
Savannah, who was diagnosed with Stage II Colorectal CancerColorectal Cancer

Stage II Colorectal Cancer: Savannah's Survivor Story

Patient Info: Savannah Kaspar, Female, Under 40 | Stage II

Biomarkers: Lynch syndrome genetic testing negative

As of March 2024, Savannah had completed partial colectomy and 4 rounds of adjuvant chemotherapy for Stage II sigmoid colon cancer and had entered surveillance with bloodwork every 3 months.

MD Anderson
OutcomeSurvivorship / Surveillance
Shannon, who was diagnosed with Stage II Colorectal CancerColorectal Cancer

Stage II MSI-High Colorectal Cancer: Shannon's Survivor Story

Patient Info: Shannon, Female, Under 40 | Stage II

Biomarkers: MSI-H; Lynch syndrome; MLH1 mutation

As of October 2023, Shannon had no recurrence described while approaching year 5 after Stage IIA colon cancer surgery and continued intensive Lynch syndrome surveillance.

The Patient Story
OutcomeCancer-Free / NED
Amanda, who was diagnosed with Stage II Colorectal CancerColorectal Cancer

Stage II Colorectal Cancer: Amanda's Survivor Story

Patient Info: Amanda, Female, Under 40 | Stage II

Biomarkers: Genetic mutations involving colon, kidney, and skin cancer risk were reported; specific genes were not named

As of May 2023, Amanda had completed surgery and chemotherapy for Stage IIA sigmoid colon cancer and was in close surveillance, with CT scans every 6 months, bloodwork every 3 months, colonoscopy follow-up, and normal cancer-marker bloodwork.

The Patient Story
OutcomeSurvivorship / Completed Treatment
Amy, who was diagnosed with Stage III Colorectal CancerColorectal Cancer

Stage III MSI-High Colorectal Cancer: Amy's Patient Story

Patient Info: Amy Hart, Female, Under 40 | Stage III

Biomarkers: Lynch syndrome; tumor described as Lynch-related but not MSI-high

As of March 2023, Amy’s story described Stage IIIB colorectal/rectal cancer diagnosis, Lynch syndrome confirmation, rapid start of daily radiation, and major surgery planning; no completed-treatment, recurrence, NED, or cancer-free status was stated.

The Patient Story
OutcomeCare Ongoing
A patient, who was diagnosed with Breast CancerBreast Cancer

Rare breast blood-vessel cancer (angiosarcoma) in a teenage girl

Patient Info: Anonymized, Female

Biomarkers: Testing for Li-Fraumeni syndrome and POT1 mutation was inconclusive; no inherited cancer predisposition was established

She remained in remission 3 years after diagnosis and continued annual MRI surveillance of the reconstructed and opposite breasts.

PubMed Central
OutcomeCancer-Free / NED
Sue, who was diagnosed with Breast CancerBreast Cancer

BRCA2 Breast Cancer: Sue's Survivor Story

Patient Info: Sue Friedman, Female, Under 40

Biomarkers: BRCA2 mutation

As of February 2023, Sue Friedman was a long-term breast cancer survivor and founder of FORCE after a BRCA2-associated breast cancer and recurrence; the video is educational and does not state current active disease, NED, or metastatic status for Sue.

The Patient Story
OutcomeSurvivorship / Completed Treatment
JJ, who was diagnosed with Stage IV Colorectal CancerColorectal Cancer

I was in Disbelief When I got Colon Cancer

Patient Info: JJ Singleton, Male, Under 40 | Stage IV

Biomarkers: Lynch syndrome

Metastatic Site: Abdominal wall; lymph nodes

After surgery and 12 rounds of FOLFOX, JJ had a clean scan and colonoscopy, but about 6 weeks later cancer recurred outside the colon with spread to the abdominal wall and lymph nodes.

The Patient Story
OutcomeSetback / Progression
Lucy, who was diagnosed with Stage II Breast CancerBreast Cancer

Stage II Triple-Negative Breast Cancer: Lucy's Patient Story

Patient Info: Lucy, Female, Under 40 | Stage II

Biomarkers: BRCA1 mutation; triple-negative breast cancer

As of January 2023, Lucy had gone through fertility preservation, chemotherapy, and double mastectomy for Stage II grade 3 triple-negative breast cancer with BRCA1 mutation; no NED or recurrence status was stated.

The Patient Story
OutcomeCare Ongoing
Stephanie, who was diagnosed with Breast CancerBreast Cancer

Triple-Negative Breast Cancer: Stephanie's Survivor Story

Patient Info: Stephanie, Female, Under 40

Biomarkers: ER-negative; PR-negative; HER2-negative; genetic testing negative

As of October 2022, Stephanie had completed treatment for triple-negative breast cancer in January 2022, follow-up tests showed she was cancer-free, and she had no evidence of cancer.

Cleveland Clinic
OutcomeCancer-Free / NED
Almudena, who was diagnosed with Stage IV Colorectal CancerColorectal Cancer

Stage IV Colorectal Cancer: Almudena's Survivor Story

Patient Info: Almudena, Female, Under 40 | Stage IV

Metastatic Site: Peritoneum

As of May 2022, Almudena was cancer-free after surgery and 12 chemotherapy sessions, had been medically cleared as cured after 6 years, and continued genetics follow-up because her case was unusual for her age.

MatchTrial Historias Reales
OutcomeCancer-Free / NED
Sandra, who was diagnosed with Breast CancerBreast Cancer

Triple-Negative Breast Cancer: Sandra's Survivor Story

Patient Info: Sandra Monsonís, Female, 40s

Biomarkers: Triple-negative breast cancer; BRCA-positive

As of November 2021, Sandra felt healthy and happy after treatment for triple-negative breast cancer, BRCA-positive testing, double mastectomy, implant complication care, external prosthesis, and ovary removal to reduce future cancer risk.

MatchTrial Historias Reales
OutcomeSurvivorship / Completed Treatment
Tamara, who was diagnosed with Breast CancerBreast Cancer

Breast Cancer: Tamara's Survivor Story

Patient Info: Tamara Bumpus, Female

Biomarkers: No specific hereditary breast cancer gene identified; strong family history of breast cancer

As of November 2020, Tamara had successful breast cancer removal and DIEP reconstruction after a 2016 diagnosis, with no specific hereditary gene identified despite a strong family history; recurrence status was not reported.

Cleveland Clinic
OutcomeSurvivorship / Surveillance
Shannon, who was diagnosed with Stage II Colorectal CancerColorectal Cancer

Cancer Survivor Story: Colon Cancer (Lynch Syndrome)

Patient Info: Shannon, Female, Under 40 | Stage II

Biomarkers: Lynch syndrome; MSI-high / dMMR

As of May 2020, Shannon was considered cancer-free after surgery-only treatment for Stage IIA MSI-high/Lynch-associated colon cancer and remained on strict Lynch syndrome surveillance.

The Patient Story
OutcomeCancer-Free / NED
Heather, who was diagnosed with Breast CancerBreast Cancer

Breast Cancer: Heather's Survivor Story

Patient Info: Heather Kokinda, Female, Under 40

As of March 2018, Heather had completed chemotherapy and double mastectomy, had a clear scan before trying to conceive again, and had given birth to another daughter in July 2017.

Cleveland Clinic
OutcomeCancer-Free / NED