FOLFIRINOX: 12 Real Stories

Colorectal Cancer: Monica's Survivor Story

Patient Info: Monica Diaz

Monica reported no evidence of disease since March 17, 2025, while continuing to recover physically and emotionally.

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Rectal Cancer Treatment Complicated by a New Bleeding Disorder

Patient Info: Anonymized, female, 60s

The rectal cancer entered complete remission after surgery and 6 cycles of adjuvant chemotherapy.

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Stage IV Colorectal Adenocarcinoma: Adrienne's Patient Story

Patient Info: Adrienne, Female | Stage IV

Metastatic Site: Liver

As of June 2026, Adrienne had Stage IV colon adenocarcinoma with liver metastases, had experienced liver recurrence after intensive multimodal treatment, and was back on FOLFIRI plus Avastin.

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Stage IV rectal mucinous adenocarcinoma with pancreatic metastasis: response to chemotherapy and staged surgery

Patient Info: Anonymized, Male, 70+ | Stage IV

Biomarkers: CA 19-9 93.4 U/mL; CEA 3.4 ng/mL; pancreatic lesion biopsy consistent with colorectal origin

Metastatic Site: pancreas

As of May 2026, he had good clinical progress during 5 months of follow-up after staged treatment, including chemoradiation, FOLFOX, abdominoperineal resection, FOLFIRINOX, and Whipple resection of the pancreatic metastasis.

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My STAGE 4 Colon Cancer was Revealed by a Routine Blood Test! (NO SYMPTOMS!)

Patient Info: Jim, Male, 40s | Stage IV

Metastatic Site: Liver; lungs

Stage IV colon cancer with liver and lung metastases responded strongly to FOLFIRINOX-based chemotherapy, with tumor reduction over 70%, no detectable lung cancer on testing, and ongoing maintenance chemotherapy for remaining liver disease.

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Stage III Colorectal Cancer: Kara's Survivor Story

Patient Info: Kara Lionetta, Female | Stage III

An update to Kara's story reported that she was no evidence of disease while completing cleanup chemotherapy and planning later ileostomy reversal.

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Stage IB pancreatic adenocarcinoma with lung and pleural recurrence: long-term disease control on chemotherapy

Patient Info: Anonymized, Male, 70+ | Stage IV

Biomarkers: Metastatic pancreatic cancer in lung: CK19/MUC1/CA19-9-positive, TTF-1-negative. UGT1A1 *6 heterozygous; no actionable mutation found.

Metastatic Site: lung, pleura

As of April 2025, he remained alive on chemotherapy 6 years and 8 months after initial pancreatic surgery and 4 years and 7 months after pulmonary oligometastatic recurrence, with no new lesions and stable disease on imaging.

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Stage IV Colorectal Cancer: Dan's Survivor Story

Patient Info: Dan Trombley, Male, Under 40 | Stage IV

Metastatic Site: Liver; portal vein; duodenum

As of July 2025, after Stage IV colon cancer that had spread through much of the liver and involved the portal vein and duodenum, Dan’s cancer had not returned and he had regained strength, returned to work, and welcomed a daughter in 2023.

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Jason Randall: stage IV colorectal cancer and liver metastases

Patient Info: Jason Randall, Male, Under 40 | Stage IV

Metastatic Site: Liver; lung; tailbone/sacrum/pelvis

As of March 2024, Jason was 2.5 years off chemotherapy and 16 months with no evidence of disease after treatment for Stage IV rectosigmoid colorectal cancer.

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My Stage 4 Colorectal Cancer Story: How I Never Lost Hope

Patient Info: Jason Randall, Male | Stage IV

Metastatic Site: Liver; lungs; bone/sacrum

As of June 2023, Jason had a negative Signatera test, CT scans showing 9 months with no evidence of disease, and about 2.5 years off chemotherapy after Stage IV colorectal cancer treatment and lung ablation.

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Bilateral adrenal bleeding during bevacizumab treatment for metastatic colon cancer

Patient Info: Anonymized, Male, 50s | Stage IV

Biomarkers: RAS-mutant; BRAF-wild type; microsatellite stable.

Metastatic Site: peritoneum; liver; lung

Despite multiple systemic and local treatments, his metastatic colon cancer progressed in the liver and peritoneum, and he died from disease progression in November 2018.

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Aggressive Presumed Ovarian Solid Pseudopapillary Tumor With Widespread Metastases

Patient Info: Anonymized, Female | Stage Metastatic/Advanced

Metastatic Site: peritoneum|pelvic soft tissue|inguinal lymph…

The disease progressed rapidly across multiple abdominal and nodal sites. She died from disease-related complications 2 months after the oncology consultation while receiving induction chemotherapy.

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