Stage IV Colorectal Adenocarcinoma: Lauren's Patient Story

Patient Info: Lauren, Female, 40s | Stage IV

Biomarkers: No actionable biomarkers reported; tumor testing suggested Lynch syndrome/hereditary pattern was unlikely; germline genetic testing pending

Lauren had Stage IV signet-ring cell colon cancer diagnosed after obstruction and emergency surgery with colostomy. As of July 2025, she was receiving traditional colorectal chemotherapy and awaiting germline genetic testing; remission was not stated.

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Primary perianal Paget disease: clear margins and disease-free 2-year follow-up after local excision

Patient Info: Anonymized, Male

Biomarkers: Cytokeratin 7 strongly positive; immunohistology suggestive of primary perianal Paget disease

At 2-year follow-up, he remained disease-free after wide local excision with clear margins, temporary defunctioning colostomy, delayed flap closure, and later colostomy reversal.

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Metastatic colorectal cancer treated with chemotherapy, cytoreductive surgery and HIPEC

Patient Info: Anonymized, Female, 40s | Stage IV

Metastatic Site: peritoneum, liver

She recovered sufficiently to be discharged home after cytoreductive surgery with HIPEC despite postoperative bone-marrow suppression, anastomotic dehiscence and pelvic sepsis.

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Stage III Colorectal Cancer: James's Survivor Story

Patient Info: James, Male | Stage III

James had Stage IIIC / possible Stage IV rectal cancer with major lymph node involvement and an uncertain liver spot. After chemotherapy, radiation, multiple surgeries, permanent colostomy, and adjuvant chemotherapy, he later reported no evidence of disease.

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Colorectal Cancer: Crystal's Survivor Story

Patient Info: Crystal, Female

Crystal completed limited chemotherapy and multiple major surgeries for colon cancer complicated by bladder involvement and infection risk. She lost her bladder and adapted to ostomy changes. No explicit NED, recurrence, or active-disease status was given.

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Stage IV Colorectal Cancer: Crystal's Survivor Story

Patient Info: Crystal, Female | Stage IV

Metastatic Site: Bladder involvement

As of May 2025, Crystal was living after major surgery for Stage IV colon cancer involving the bladder, with both colostomy and urostomy bags and an emphasis on mental health, support, and quality of life.

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Lynch syndrome bifocal colon cancer: complete pathological remission after sintilimab

Patient Info: Anonymized, Male, 40s | Stage III

Biomarkers: Lynch-associated colon cancer with MSI-H and KRAS/NRAS/BRAF wild type; tumor markers were low or near normal.

As of April 2025, pathology after proximal colectomy showed tumor regression grade 0 with complete pathological remission, and follow-up found no recurrence or metastasis.

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Stage III Colorectal Cancer: Heather's Survivor Story

Patient Info: Heather Russell, Female, Under 40 | Stage III

In her fifth year of remission at the time of the 2025 story after treatment for Stage III rectal cancer; she had returned to family and working life, with some lasting treatment effects.

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Colorectal Cancer: Cattie's Patient Story

Patient Info: Cattie Fleming, Female

Cattie remained on chemotherapy, and her most recent scans showed that treatment was effective.

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Stage II Colorectal Cancer: Tracy's Survivor Story

Patient Info: Tracy, Female, 40s | Stage II

As of February 2025, Tracy was in post-treatment survivorship after Stage IIB colorectal cancer treated with 28 days of Xeloda chemoradiation, colostomy surgery in December 2015, and discontinued post-surgery chemotherapy.

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Stage IV Colorectal Cancer: Rachael's Patient Story

Patient Info: Rachael, Female, Under 40 | Stage IV

Metastatic Site: Ovaries; liver

As of January 2025, Rachael had completed intensive chemotherapy for Stage IV sigmoid colon cancer involving the ovaries and liver and was awaiting scans to determine whether liver surgery and HIPEC would be next.

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How I Found Out I Had Stage 4 Colon Cancer!

Patient Info: Rachael Marie, Female, Under 40 | Stage IV

Metastatic Site: ovaries, liver

Rachael completed 12 cycles of FOLFOX/oxaliplatin; colonoscopy looked clear, liver lesions had shrunk, and no new lesions were reported, with further surgical planning pending.

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Stage IV Colorectal Cancer: Roshonda's Survivor Story

Patient Info: Roshonda Clark, Female, 40s | Stage IV

Roshonda completed chemoradiation and permanent-colostomy surgery, returned to work, and described living day by day with recurrence worries but no active treatment reported.

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Stage IV Colorectal Cancer: Roshonda's Patient Story

Patient Info: Roshonda, Female | Stage IV

Metastatic Site: Lung

As of January 2025, Roshonda was living after treatment for Stage IV rectal cancer with a lung spot, including chemoradiation, IV chemotherapy, and permanent colostomy surgery.

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Gastric cancer recurring in the rectum about 20 months after gastrectomy

Patient Info: Anonymized, Male, 60s | Stage IV

Metastatic Site: rectum, peritoneum

Metastatic gastric adenocarcinoma involved the rectum and pericolonic fat, with peritoneal nodules seen at surgery. He died 6 months after the rectal operation.

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Rectal cancer surgery in a man with situs inversus and prior major stroke

Patient Info: Anonymized, Male, 60s

He recovered from surgery and had no tumor recurrence or metastasis during 24 months of follow-up.

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Jazz: Stage III / borderline Stage IV colorectal cancer

Patient Info: Jazz, Male | Stage III

As of November 2024, Jazz was in active treatment for Stage III / borderline Stage IV colorectal cancer after colostomy surgery, chemotherapy, stomach tumor removal, and radiation, with surgery still planned for the remaining tumor.

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Stage III Colorectal Cancer: Jazz's Patient Story

Patient Info: Jazz Page, Male | Stage III

As of November 2024, Jazz was still in active treatment planning with radiation, oral chemotherapy pills, and final surgery expected; no post-treatment remission status was reported.

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Stage III Colorectal Cancer: Jessenia's Patient Story

Patient Info: Jessenia, Female, Under 40 | Stage III

As of September 2024, Jessenia had completed major treatment steps and was adapting to the physical and emotional effects of treatment, including a temporary colostomy; a clear remission/NED status was not stated.

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Stephanie’s Stage 3 Colon Cancer Story

Patient Info: Stephanie, Female, Under 40 | Stage III

CT and PET imaging after treatment showed no active colon cancer. Her October 2023 scans were clear and her oncologist described the cancer as in remission; unchanged spots in the liver and lung continued to be monitored.

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Stage 0 Colorectal Cancer: Tracy's Survivor Story

Patient Info: Tracy Robert, Female, 40s | Stage 0

Biomarkers: Chemotherapy metabolism gene variant reported; exact gene not stated

As of August 2024, Tracy was a long-term survivor. After chemoradiation and surgery, pathology showed Stage 0/no remaining cancer, and no recurrence was reported.

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Lung squamous cell carcinoma spreading to bone and intestine

Patient Info: Anonymized, Male, 50s | Stage IV

Biomarkers: PD-L1 positive in almost all tumor cells

Metastatic Site: bone (left femur), intestine, abdomen

Despite chemotherapy, immunotherapy and radiation, the lung cancer progressed with intestinal and extensive abdominal metastases, cachexia and gastrointestinal bleeding. Palliative care was planned, but he chose discharge and received no further treatment.

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Rectal cancer with an isolated vaginal metastasis treated with repeat surgery

Patient Info: Anonymized, female, 70+ | Stage IV

Metastatic Site: vagina

After resection of an isolated vaginal metastasis, she was receiving ongoing adjuvant chemotherapy with good tolerance.

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Ovarian Clear Cell Cancer Surgery Followed by a Serious Bowel Complication

Patient Info: Anonymized, Female

She recovered from the bowel perforation and reactive subdiaphragmatic cyst, stopped infection medication after negative cultures, and was discharged 78 days after the initial surgery while additional anticancer treatment remained planned.

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