Stage 1 lung adenocarcinoma: complete response to cryoablation

Patient Info: Anonymized, Male, 70+

Biomarkers: Not reported for this patient

Two years after cryoablation, he remained clinically stable with no signs of local recurrence or distant metastasis.

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Stage IV Colorectal Cancer: Amy's Patient Story

Patient Info: Amy Nicole, Female, Under 40 | Stage IV

Metastatic Site: liver; lymph nodes near kidneys/retroperitoneal lymph…

As of June 2024, Amy was living with recurrent Stage IV colon cancer and was on an immunotherapy clinical trial that improved quality of life compared with chemotherapy, though she did not describe remission or NED.

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Stage IV Colorectal Cancer: Jessica's Survivor Story

Patient Info: Jessica Dazzler, Female, Under 40 | Stage IV

Biomarkers: FoundationOne testing performed; exact mutation not stated

Metastatic Site: lungs, spine, rib

As of May 2024, Jessica said it took 3 years and 4 months to reach no evidence of disease after Stage IV colorectal cancer, though she remained anxious about future scans and possible circulating cancer.

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Freezing treatment (cryoablation) used to manage slow-growing triple-negative breast cancer

Patient Info: Anonymized, Female | Stage Metastatic/Advanced

Biomarkers: ER-negative; PR-negative; HER2-negative; androgen receptor-positive in original tumor; Ki-67 5% initially and 10% at recurrence

At 29 months after recurrence diagnosis and 20 months after the first cryoablation, no viable breast tumor was seen at treated sites, axillary nodes were unchanged, pain was absent, and she remained active and independent.

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Stage IIIB to metastatic rectal cancer: setback and treatment journey

Patient Info: Justine, Female, Under 40 | Stage IV

Metastatic Site: Liver; lung

As of March 2024, Justine was living with metastatic rectal cancer involving liver and lung, described as treatable but not curable, after surgery, permanent ileostomy, IV chemotherapy, liver ablation, lung SBRT, and Y-90 liver radioembolization.

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Stage IV Colorectal Cancer: Bobbi's Survivor Story

Patient Info: Bobbi Ratliff, 50s | Stage IV

Metastatic Site: liver|lungs

On February 1, 2024, scans showed no evidence of cancer after multimodal treatment for Stage IV disease.

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Pembrolizumab led to complete response before surgery for metastatic dMMR colon cancer

Patient Info: Anonymized, male, 70+ | Stage IV

Biomarkers: dMMR/MSI-H; MLH1 loss; PMS2 loss; BRAF mutation; heterozygous MUTYH p. pathogenic variant

Metastatic Site: liver

The 2023 liver resection showed a pathological complete response with no residual tumor, and he entered follow-up without additional therapy.

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32-year-old woman with Stage IV rectal cancer, liver and lung metastases, targeted chemotherapy, surgery, ablation, radiation, and ongoing chemotherapy

Patient Info: Anonymized, Female, Under 40 | Stage IV

Biomarkers: KRAS wild-type; NRAS wild-type; BRAF wild-type

Metastatic Site: Liver | Lung | Presacral/perirectal lymph nodes

As of the story endpoint around December 2020, she was 5 years into treatment for Stage IV rectal cancer after multiple systemic regimens, bowel/liver/lung surgery, liver recurrence treatment, ablation, lung surgery, TOMO radiation, and ongoing chemotherapy.

Stage III KRAS Non-Small Cell Lung Cancer: Terri's Survivor Story

Patient Info: Terri Conneran, Female | Stage III

Biomarkers: KRAS-mutated; PD-L1 level reviewed/tested

As of March 2021, Terri had Stage IIIA KRAS-mutated NSCLC with 3 local recurrences treated over time and had again reached no evidence of disease while continuing close surveillance and advocacy through KRAS Kickers.

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