Metastatic Clear Cell Ovarian Cancer Complicated by Treatment-Related Sarcoidosis

Patient Info: Anonymized, Female, 60s | Stage Metastatic/Advanced

Metastatic Site: peritoneum

During a treatment holiday, biopsy and laboratory evaluation showed treatment-related sarcoidosis rather than ovarian-cancer spread in the enlarged lymph nodes. After prednisone, the sarcoidosis resolved and imaging showed no progression of the clear cell ovarian cancer; she remained clinically well 4 months later.

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BRCA Ovarian Cancer: Christie's Patient Story

Patient Info: Christie Siebel, female

Biomarkers: BRCA mutation

At the latest update, Christie was doing well and having a CA125 blood test every 3 months for ovarian cancer follow-up.

MD AndersonRead more →

Immature Ovarian Teratoma Followed by Anti-NMDAR Encephalitis

Patient Info: Anonymized, Female

Biomarkers: AFP 67.6 ng/mL; CA-125 89 at presentation

After 4 cycles of chemotherapy, her neurological deficits fully recovered and she could walk independently, with mild stuttering improving through speech therapy.

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Ovarian Cancer: Shelley's Patient Story

Patient Info: Shelley O’Keefe, female

Shelley was nearing the end of chemotherapy, rebuilding her strength, and returning to demanding golf activity with strong family and community support.

Early-Stage Primary Ovarian Synovial Sarcoma Managed With Surgery and Surveillance

Patient Info: Anonymized, Female, Under 40

Biomarkers: SS18 gene rearrangement confirmed by FISH; CA-125 10.9 U/mL

Serial CT and PET imaging showed no residual disease, recurrence, or metastasis. She remained disease-free 27 months after diagnosis.

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Ovarian Cancer: Dana's Patient Story

Patient Info: Dana Kivel, female

Dana was living with recurrent, metastatic granulosa cell ovarian cancer and taking an aromatase inhibitor for a current tumor.

Stage 4 Ovarian Cancer Discovered During Trigeminal Neuralgia Evaluation

Patient Info: Anonymized, Female, 50s | Stage IV

Three months after surgery, she had recovered well from debulking and 6 total chemotherapy cycles, with complete macroscopic clearance achieved at surgery. Trigeminal-neuralgia symptoms persisted and continued to require daily medication.

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MSI-High Malignant Struma Ovarii With Lung and Liver Metastases 17 Years Later

Patient Info: Anonymized, Female, 50s | Stage Metastatic/Advanced

Biomarkers: NRAS, and ATM mutations; Ki-67 approximately 15%–29%

Metastatic Site: lungs|liver

She remained asymptomatic and tolerated pembrolizumab without obvious adverse effects after 4 doses, with follow-up imaging planned for metastatic lung and liver disease.

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Rapidly Progressive Stage IIIA2 Ovarian Cancer With Anaplastic Features

Patient Info: Anonymized, Female, Under 40 | Stage Metastatic/Advanced

Biomarkers: CA-125 419 IU/mL; CA19-9 elevated; lactate dehydrogenase elevated

Metastatic Site: lungs|liver

Within 30 days of surgery, the cancer had progressed with a large retroperitoneal nodal mass and new lung and liver metastases. She died from advanced ovarian cancer 5 weeks after surgery.

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Kidney Complications After Treatment for Stage IV Ovarian Cancer

Patient Info: Anonymized, Female, 60s | Stage IV

Metastatic Site: peritoneum|left lymph node

No further ovarian-cancer progression was observed during the 10 months after kidney biopsy. The nephrotic syndrome reached partial remission after immunosuppressive treatment was stopped and supportive care continued.

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Aggressive Presumed Ovarian Solid Pseudopapillary Tumor With Widespread Metastases

Patient Info: Anonymized, Female | Stage Metastatic/Advanced

Metastatic Site: peritoneum|pelvic soft tissue|inguinal lymph…

The disease progressed rapidly across multiple abdominal and nodal sites. She died from disease-related complications 2 months after the oncology consultation while receiving induction chemotherapy.

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Ovarian Cancer: Lauren's Survivor Story

Patient Info: Lauren Wells, Female, Under 40

Lauren was described as cancer-free and making a strong recovery while continuing physical, occupational, and speech therapy.

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Ovarian Cancer: Elle's Patient Story

Patient Info: Elle Simone, female

Elle was dealing with an ovarian cancer recurrence while continuing her work and advocacy.

Stage III Ovarian Cancer: Jackie's Survivor Story

Patient Info: Jackie Page, Female, 50s | Stage III

In remission with no sign of recurrent disease at the September 2020 publication, while continuing treatment on the clinical trial.

Dana-FarberRead more →

Ovarian Fibrosarcoma Recurring Rapidly After Debulking Surgery

Patient Info: Anonymized, Female, 40s

Biomarkers: Ki-67 greater than 20%; vimentin diffusely positive; muscle-specific antigen weakly positive

The cancer recurred with a new pelvic mass and ascites 3 months after surgery. Her condition was too poor for chemotherapy, and she died on the second day of palliative hospital care.

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Emergency Surgery for a Malignant Brenner Tumor Causing Bowel Obstruction

Patient Info: Anonymized, Female, 60s

Biomarkers: CA-125 184.2 U/mL

A 62-year-old woman with a rare malignant Brenner tumor required emergency surgery after the ovarian mass caused bowel obstruction and a sealed perforation.

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Ovarian Cancer: Kimberly's Survivor Story

Patient Info: Kimberly Richardson, 50s

Kimberly described living with no evidence of disease while undergoing frequent tumor-marker surveillance because granulosa cell tumors can recur.

Ovarian Cancer: Jamie's Patient Story

Patient Info: Jamie, female, Under 40

By age 28, Jamie was rebuilding physical strength after two surgeries and had trained as an OCRA peer mentor.

Ovarian Wilms tumor with early abdominal recurrence

Patient Info: Anonymized, Female, Under 40

Biomarkers: WT1-positive; residual tumor MyoD1-positive

After 3 months of radiation and a further 3 months of chemotherapy, PET showed no FDG-avid malignancy.

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Ovarian Wilms tumor arising in a mature cystic teratoma

Patient Info: Anonymized, Female, Under 40

Biomarkers: WT1-positive; PAX8-positive

After the diagnosis was revised to ovarian Wilms tumor, she was advised to see a gynecologic oncologist but did not return for follow-up.

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Ovarian cancer that later spread to an axillary lymph node

Patient Info: Anonymized, Female, 60s | Stage IV

Metastatic Site: axillary lymph nodes

After later peritoneal progression, additional treatment brought the disease to a stable state through her last recorded visit in July 2019.

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Ovarian cancer presenting with axillary lymph-node spread

Patient Info: Anonymized, Female, Under 40 | Stage IV

Metastatic Site: axillary lymph nodes

A 39-year-old woman with high-grade serous ovarian cancer had confirmed spread to an axillary lymph node at diagnosis and underwent extensive cytoreductive surgery.

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Stage IV ovarian cancer with axillary lymph-node spread

Patient Info: Anonymized, Female, 50s | Stage IV

Metastatic Site: axillary lymph nodes

A 58-year-old woman with ovarian serous carcinoma and axillary lymph-node spread received chemotherapy, cytoreductive surgery, and postoperative chemotherapy.

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Stage III BRCA1 Ovarian Cancer: Patty's Patient Story

Patient Info: Patty Klein, Female | Stage III

Biomarkers: BRCA1 mutation

Patty was able to continue the olaparib plus BKM120 clinical trial as long as her tumor remained controlled. She later died.