Bilateral adrenal bleeding during bevacizumab treatment for metastatic colon cancer

Patient Info: Anonymized, Male, 50s | Stage IV

Biomarkers: RAS-mutant; BRAF-wild type; microsatellite stable.

Metastatic Site: peritoneum; liver; lung

Despite multiple systemic and local treatments, his metastatic colon cancer progressed in the liver and peritoneum, and he died from disease progression in November 2018.

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Perforated appendicitis after surgery for stage I rectal cancer

Patient Info: Anonymized, Male, 70+ | Stage I

He recovered well after appendicectomy, was doing well at the four-week review, and remained under intensive rectal-cancer follow-up with community stoma and wound-care support.

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Rectosigmoid cancer first discovered through bone marrow spread

Patient Info: Anonymized, Female, Under 40 | Stage IV

Metastatic Site: bone marrow|ovaries|bone

She died from overwhelming sepsis 1 week after the diagnosis of metastatic rectosigmoid cancer.

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Budesonide resolved severe capecitabine-related diarrhoea during rectal cancer treatment

Patient Info: Anonymized, Female, 70+ | Stage II

The treatment-resistant diarrhoea resolved within two weeks of starting budesonide, and follow-up endoscopy and biopsies showed complete resolution of the bowel inflammation.

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Pemphigus Vulgaris After Rectal Cancer Surgery and Ileostomy

Patient Info: Anonymized, Female, 50s | Stage Metastatic/Advanced

Clinicians found no evidence of residual internal malignancy during evaluation of her skin disease, and the pemphigus lesions healed after rituximab with remission maintained for 14 months.

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Colon Cancer Discovered During Emergency Surgery for Intussusception

Patient Info: Anonymized, Female, 70+

She recovered from emergency surgery, was managed conservatively without chemotherapy, and continued regular follow-up after discharge to a nursing home.

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Ureter-to-Colon Fistula After Surgery for Sigmoid Cancer

Patient Info: Anonymized, Male, 60s

He recovered from repair of the postoperative ureterocolic fistula and returned to work six months after the original cancer operation, although he remained very tired.

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Metastatic Rectal Cancer Complicated by Salmonella-Related Bowel Perforation

Patient Info: Anonymized, Male, 60s | Stage IV

Metastatic Site: liver; lungs

Postoperative infection and wound complications delayed palliative chemotherapy, and he died from metastatic rectal cancer one year later.

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