Stage III Breast Cancer: Elizabeth's Survivor Story

Patient Info: Elizabeth, 40s | Stage III

Biomarkers: Cancer described as highly hormone-dependent.

Elizabeth said she was in remission and no longer required treatment after lumpectomy, chemotherapy, radiation, and an aromatase-inhibitor clinical trial.

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Stage III Colorectal Adenocarcinoma: Anne's Survivor Story

Patient Info: Anne, Under 40 | Stage III

Anne was declared cancer-free in December 2017 and reports doing well 7 years after treatment.

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Stage III HER2-Positive Invasive Ductal Carcinoma: Dorothy's Survivor Story

Patient Info: Dorothy Paterson, Female, 40s | Stage III

Biomarkers: HER2-positive

As of November 2016, Dorothy had remained cancer-free since completing treatment for Stage III HER2-positive invasive ductal carcinoma in April 1999.

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Ovarian Cancer With Severe Dermatomyositis During Treatment

Patient Info: Anonymized, female, 60s | Stage III

Biomarkers: BRCA1 mutation

She continued paclitaxel and carboplatin while being treated for severe dermatomyositis and later described herself as finally on the mend.

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Stage III gastric neuroendocrine carcinoma with signet-ring cells remains recurrence-free 6 years after surgery

Patient Info: Anonymized, Male, 60s | Stage III

Biomarkers: synaptophysin-positive; CD56-positive; Ki-67 23.1%

At 72 months, or 6 years, after surgery, he remained alive without recurrence.

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Stage III Breast Cancer: Zhan's Survivor Story

Patient Info: Zhan Shen Ya Dian Na | Stage III

She reports that her breast cancer is in remission and continues hormone therapy.

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High-Grade Serous Ovarian Cancer With Markedly Elevated Amylase

Patient Info: Anonymized, female | Stage III

At 6 months, she was receiving 3 additional chemotherapy cycles after an excellent initial clinical and imaging response, with later marker changes reflecting periods of progression and response.

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Stage III Ovarian Cancer Treated Over Years Before a Separate Oral Cancer

Patient Info: Anonymized, female, 40s | Stage III

Biomarkers: BRCA1 mutation

After prolonged treatment for recurrent ovarian cancer, follow-up visits documented her as free from ovarian disease.

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Ovarian Cancer Recurrence Complicated by a Benign Surgical Stitch Reaction

Patient Info: Anonymized, female, 40s | Stage III

Diffuse peritoneal relapse was confirmed, and she remained on third-line chemotherapy with persistent evidence of ovarian cancer.

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Stage III BRCA1 Ovarian Cancer: Meredith's Survivor Story

Patient Info: Meredith Ippolito, female | Stage III

Biomarkers: BRCA1 mutation

Meredith was told she was cancer-free in April 2009 and continued follow-up visits every 6 months.

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Stage IIIB lung adenocarcinoma with separate papillary renal cell carcinoma: doing well more than 6 years after revised diagnosis

Patient Info: Anonymized, Female, 40s | Stage III

Biomarkers: Lung tumor: TTF-1-positive; PET-avid. Kidney lesion: PET-negative; later papillary renal cell carcinoma. No lung molecular biomarkers reported.

As of February 2014, she was doing well more than 6 years after the initial diagnosis, after the diagnosis was revised from presumed Stage IV lung cancer to Stage IIIB lung adenocarcinoma plus a separate papillary renal cell carcinoma.

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Stage IIIA NSCLC with superior vena cava tumor thrombus: complete response to radiation and erlotinib

Patient Info: Anonymized, Male, 60s | Stage III

Biomarkers: EGFR protein expression positive; EGFR gene mutation not tested because tumor sample was inadequate

Radiation plus erlotinib led to complete response of the primary lung tumor at 6 months, disappearance of the SVC thrombosis at 9 months, and no progression during 45 months of close follow-up on maintenance erlotinib.

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Stage III signet-ring gastric cancer is diagnosed only after repeated negative biopsies

Patient Info: Anonymized, Male, 50s | Stage III

He was alive at the latest follow-up after surgery and 8 courses of XELOX chemotherapy.

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Stage III Ovarian Cancer Diagnosed With a Separate Vaginal Cancer

Patient Info: Anonymized, 50s | Stage III

A whole-body PET scan 4 weeks after treatment found no active malignant disease, and she continued regular follow-up.

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Stage III sigmoid colon invasive micropapillary carcinoma treated with sigmoidectomy and modified FOLFOX6

Patient Info: Anonymized, Male, 70+ | Stage III

Biomarkers: CEA normal; CA 19-9 normal; MUC1 inside-out staining pattern in micropapillary component

After diagnostic endoscopic resection, sigmoidectomy with regional lymph node resection, and 6 cycles of modified FOLFOX6, he was in good condition with no evidence of recurrence 12 months after surgery.

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Stage IIIA pleomorphic lung cancer treated with surgery, chemotherapy, and radiation

Patient Info: Anonymized, Male, Under 40 | Stage III

Alive 14 months after surgery without evidence of tumor recurrence after complete resection, adjuvant chemotherapy, oral S-1, and radiation.

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Stage III Ovarian Cancer in a BRCA1 Carrier Treated With Long-Term Maintenance Therapy

Patient Info: Anonymized, 50s | Stage III

Biomarkers: BRCA1 mutation

After long-term maintenance therapy, she had no evidence of ovarian cancer at the latest follow-up.

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Recurrent Stage III Ovarian Cancer in a BRCA2 Carrier Treated Over Many Years

Patient Info: Anonymized, 40s | Stage III

Biomarkers: BRCA2 mutation

She later developed a separate aggressive oral squamous cell carcinoma and died in 2011 from acute airway obstruction during progression of that cancer.

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Stage III Triple-Negative Breast Cancer: Bridgette's Survivor Story

Patient Info: Bridgette, Female, 60s | Stage III

Biomarkers: Triple-negative breast cancer

Bridgette completed treatment and described herself as being in remission and free of cancer. Fear of recurrence continued to affect her survivorship.

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Stage III Ovarian Cancer in a BRCA1 Carrier With Long-Term Disease Control

Patient Info: Anonymized, 60s | Stage III

Biomarkers: BRCA1 mutation

At the latest follow-up in January 2012, she had no recurrence of ovarian cancer and was well.

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Recurrent Stage III Ovarian Cancer in a BRCA1 Carrier Treated With Multiple Therapies

Patient Info: Anonymized, female, 40s | Stage III

Biomarkers: BRCA1 mutation

By late 2011, hilar nodal disease was slowly progressing and bevacizumab was started for the recurrent ovarian cancer.

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Recurrent Stage III Ovarian Cancer Complicated by Severe Kidney Injury

Patient Info: Anonymized, female, 70+ | Stage III

After further intra-abdominal cancer progression and severe kidney injury, she developed seizures, encephalopathy, and limb ischemia and died 1 week after hospitalization in May 2011.

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Triple-negative glycogen-rich clear cell carcinoma of the breast: chemotherapy, mastectomy, and radiation

Patient Info: Anonymized, Female, 50s | Stage III

Biomarkers: Triple-negative breast cancer with glycogen-rich clear cell features; pathology stains supported breast carcinoma.

Asymptomatic and disease-free 14 months after surgery, additional chemotherapy, and 50 Gy radiotherapy for T4N0M0 triple-negative glycogen-rich clear cell breast carcinoma.

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Stage IIIA squamous NSCLC: complete pathological response after docetaxel and lobectomy

Patient Info: Anonymized, Male, 60s | Stage III

Complete clinical response after 14 cycles of docetaxel was confirmed as a complete pathological response after right lobectomy.

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