CDH1 Mutation: 10 Real Stories
10 stories match CDH1 mutation. 8 of them mention gastrectomy.
Stage I Gastric Cancer: Sarah’s Survivor Story
At 25, this patient learned through genetic testing that they carried a CDH1 mutation, which substantially increased the risk of stomach cancer. Because stomach cancer can be difficult to detect early in people with this mutation, they chose a preventive…
Read this storyBreast Cancer: Linda’s Patient Story
Linda Stokes was diagnosed with breast cancer in April 2015. Genetic testing then found a germline CDH1 mutation, which also placed her at high hereditary risk for diffuse gastric cancer. In June 2015, Linda chose bilateral mastectomy rather than the…
Read this storyGastric Cancer: Emily’s Patient Story
In 2014, this patient learned at age 25 that they carried a CDH1 mutation associated with a high risk of stomach cancer. The initial plan was careful surveillance while the patient and a spouse considered starting a family. Two endoscopies showed no evidence…
Read this storyStage I Gastric Cancer Patient Story
One of two sisters from a family affected by stomach, colorectal, and breast cancer tested positive for a CDH1 mutation in early 2016. The sisters were ages 31 and 34 when they faced the decision together. Their doctors explained that hereditary diffuse…
Read this storyStage I Gastric Cancer Patient Story
The second of two sisters from a family affected by stomach, colorectal, and breast cancer tested positive for a CDH1 mutation in early 2016. The women were ages 31 and 34 when they faced the decision together. Because reliable screening for hereditary…
Read this storyGastric Cancer: Sandra’s Patient Story
Sandra Sankar Poukkula was diagnosed with gastric cancer at age 39. Genetic testing identified a CDH1 mutation inherited from her father. Her brother had previously died from gastric cancer at age 37, giving the diagnosis a strong family context. Sandra…
Read this storyGastric Cancer: Adriana’s Patient Story
Adriana Walsh lost her father, Steve, to stomach cancer in 2006 when she was 13. In 2009, genetic testing showed that Adriana carried the same CDH1 mutation associated with her family’s cancer history. An endoscopy in August later found evidence of stomach…
Read this storyGastric Cancer: Gretchen’s Survivor Story
Gretchen Borzi learned in 2009 that she carried a germline CDH1 mutation, placing her at very high risk for hereditary diffuse gastric cancer. After considering the recommendation for preventive surgery, she underwent total gastrectomy in July 2011 at age 40…
Read this storyInvasive Lobular Carcinoma: Gretchen’s Survivor Story
Because a germline CDH1 mutation also increased her risk of lobular breast cancer, Gretchen Borzi alternated mammograms and breast MRI every 6 months. In March 2014, MRI identified a small abnormal area that was confirmed by biopsy as invasive lobular…
Read this storyGastric Cancer: Laura’s Patient Story
Laura McFetridge Ayala learned at age 22 that she carried a CDH1 mutation linked to hereditary diffuse gastric cancer. Five months later, a biopsy found cancer, which affected the timing of her surgery. She underwent total gastrectomy in August 2011, becoming…
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