Stage IV Colorectal Cancer: Dan's Survivor Story

Patient Info: Dan Trombley, Male, Under 40 | Stage IV

Metastatic Site: Liver; portal vein; duodenum

As of July 2025, after Stage IV colon cancer that had spread through much of the liver and involved the portal vein and duodenum, Dan’s cancer had not returned and he had regained strength, returned to work, and welcomed a daughter in 2023.

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Stage III Colorectal Cancer: Ian's Survivor Story

Patient Info: Ian, Male, Under 40 | Stage III

Ian had Stage III sigmoid colon cancer treated with robotic laparoscopic surgery and adjuvant FOLFOX-based chemotherapy. As of July 2025, he described negative ctDNA tests and clear scans, with his oncologist comfortable saying he had been NED since surgery on December 13, 2022.

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Breast Cancer: Dolly's Survivor Story

Patient Info: Dolly Chua, Female

As of July 2025, Dolly had completed surgery for breast and thyroid tumors, described feeling wonderful and strong, and remained connected to follow-up care; the source does not explicitly state NED or recurrence status.

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Stage III Colorectal Cancer: Jackson's Survivor Story

Patient Info: Jackson, Male, Under 40 | Stage III

Jackson completed surgery and chemotherapy for Stage III colon cancer. After his final infusion on January 28, 2025, Signatera was negative, chest and abdomen CTs were clear, tumor-marker bloodwork was negative, and he was declared in remission/no evidence of disease; a later CT in June 2025 was also clear.

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HR-Positive Breast Cancer: Sara's Patient Story

Patient Info: Sara Glenn, Female, Under 40

Biomarkers: TP53 mutation / Li-Fraumeni syndrome; ER-positive; HER2-negative

As of June 2025, Sara had completed bilateral mastectomy and reconstruction for ER-positive, HER2-negative breast cancer and was on planned 10-year tamoxifen plus intensive Li-Fraumeni syndrome surveillance for herself and her daughters.

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Stage III Lung Cancer: Alexis's Survivor Story

Patient Info: Alexis, Female, Under 40 | Stage III

Biomarkers: No lung tumor biomarker reported

Alexis had Stage III pulmonary neuroendocrine/carcinoid cancer treated with removal of the entire left lung and 4 months of adjuvant pill chemotherapy. Follow-up scans after chemotherapy were clear, and her doctor called the status no evidence of disease; she continues long-term surveillance.

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Stage I Breast Cancer: Krista's Patient Story

Patient Info: Krista, Female | Stage I

Biomarkers: ATM mutation; hormone receptor-positive; HER2-negative; Oncotype DX score 1

As of May 2025, Krista had undergone double mastectomy with flap reconstruction for Stage IA hormone receptor-positive, HER2-negative breast cancer and was taking tamoxifen with minimal early side effects.

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Stage I Colorectal Cancer: Monica's Survivor Story

Patient Info: Monica Dean, Female, 40s | Stage I

As of April 2025, Monica was disease-free after Stage I colorectal cancer was removed with lower anterior resection; pathology showed clean margins and no lymph node involvement, and she did not need chemotherapy or radiation.

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Stage 0 Invasive Lobular Carcinoma: Kathleen's Survivor Story

Patient Info: Kathleen, Female | Stage 0

Kathleen completed surgery-focused treatment for DCIS with a very small invasive lobular component. No chemotherapy was needed, endocrine therapy was discussed but not required, and she continued imaging surveillance and advocacy in the flat community.

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Stage III Colorectal Adenocarcinoma: Chloe's Survivor Story

Patient Info: Chloe, Female | Stage III

Biomarkers: Familial adenomatous polyposis

As of April 2025, Chloe was in remission after emergency surgery with a stoma and 4 rounds of IV/oral chemotherapy for Stage III FAP-associated colon adenocarcinoma.

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Mark: Stage III Colorectal Cancer

Patient Info: Mark, Male, Under 40 | Stage III

Biomarkers: Lynch syndrome negative

As of March 2025, Mark was sharing his story after surgery and intensive chemotherapy for Stage IIIB colon cancer and had been declared to have no evidence of disease in 2021.

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Edie: Stage III Colorectal Cancer

Patient Info: Edie, Female, 50s | Stage III

As of March 2025, Edie had recovered after chemotherapy, radiation, lower anterior resection, temporary ileostomy, and reversal; lymph nodes were negative, margins were clean, and follow-up scans and colonoscopies had remained clear.

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Stage III Colorectal Cancer: Katie's Survivor Story

Patient Info: Katie, Female | Stage III

As of February 2025, Katie had no evidence of disease after surgery and 6 cycles of chemotherapy and was continuing reassuring follow-up, including ctDNA testing.

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Facing Triple-Negative Breast Cancer: Chance’s Story

Patient Info: Chance, Female, Under 40 | Stage II

Biomarkers: ER-negative; PR-negative; HER2-negative; BRCA1 mutation

As of February 2025, Chance described follow-up after Stage II BRCA1-associated triple-negative breast cancer and stated that she did not currently have cancer, while continuing close surveillance.

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Stage III Colorectal Cancer: Denelle's Survivor Story

Patient Info: Denelle, Female | Stage III

As of February 2025, Denelle had a complete response to total neoadjuvant therapy for Stage IIIB rectal cancer, avoided surgery, and was in active surveillance with scans and scopes every 3 months.

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Two sisters with invasive lobular breast cancer and a shared CDH1 mutation

Patient Info: Anonymized, Female | Stage Metastatic/Advanced

Biomarkers: Both sisters had pathogenic CDH1 p.. Breast cancers were HER2-negative; older sister also had a PTCH1 variant of uncertain significance.

As of January 2025, both sisters were under ongoing hereditary diffuse gastric cancer surveillance with annual EGD after breast cancer treatment; no signs of HDGC or metastatic breast cancer were reported.

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Stage III Colorectal Cancer: Jose's Survivor Story

Patient Info: Jose Santos, Male, 40s | Stage III

As of December 2024, more than 2 years after surgery for Stage III colorectal cancer, Jose had no evidence of disease, had adapted well to his ileostomy, and no longer had ulcerative colitis symptoms.

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Stage I Colorectal Cancer: Jay's Survivor Story

Patient Info: Jay Trevino, Male, 40s | Stage I

As of December 2024, Jay had Stage I colon cancer removed completely by laparoscopic surgery, was home within 24 hours, had a very good prognosis, and was planned for periodic blood tests and CT scans.

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Stage II Colorectal Cancer: Maddee's Survivor Story

Patient Info: Maddee Moore, Female, Under 40 | Stage II

Biomarkers: Lynch syndrome

As of October 2024, Maddee had no reported recurrence after surgery for Stage II colon cancer and remained in close surveillance because of Lynch syndrome.

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Lung Cancer: Pascal's Survivor Story

Patient Info: Pascal, Male, 60s

As of the September 2024 article update, Pascal had resumed sports, felt well, and had been in complete remission for 26 months after an immunotherapy clinical trial following chemotherapy and radiation failure.

Stage 4 lung cancer: complete resection after splenectomy

Patient Info: Anonymized, Male, 60s | Stage IV

Biomarkers: TTF-1-positive; Synaptophysin-positive; CD56-positive

Metastatic Site: spleen

No evidence of recurrence 1 year after open splenectomy/partial diaphragm resection and later R0 resection of the primary lung tumor for Stage IVB lung cancer with splenic metastasis; systemic therapy was refused.

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Sophie: Stage IV Colorectal Cancer

Patient Info: Sophie, Female | Stage IV

Biomarkers: BRAF mutation; MSI

Metastatic Site: Liver; lymph nodes; other torso lesions

As of August 2024, Sophie had been declared cancer-free after Stage IV BRAF-mutated/MSI bowel cancer responded to nivolumab/ipilimumab-based immunotherapy, with PET imaging and liver surgery biopsy showing no cancerous cells.

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Stage 0 DCIS breast cancer: disease-free after treatment

Patient Info: Erica, Female | Stage 0

Biomarkers: BRCA-negative

As of August 2024, Erica described herself as cancer-free after Stage 0 DCIS treated with double mastectomy and reconstruction, with peace of mind about recurrence risk.

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Stage IV Breast Cancer: Lisa's Patient Story

Patient Info: Lisa Ordmandy, Female, 60s | Stage IV

Metastatic Site: Spine/bone: C2 and L3 vertebrae

As of June 2024, Lisa was living with metastatic breast cancer as a chronic illness, had recovered mobility after November 2023 spine surgery, continued close MD Anderson monitoring, and was being evaluated for possible clinical trials.

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