Stage II Invasive Lobular Carcinoma: Jane's Patient Story

Patient Info: Jane, Female, 50s | Stage II

Nearly 3 years into her breast-cancer journey, she was continuing long-term hormone therapy and active patient advocacy.

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Severe postsurgical pyoderma gangrenosum after prior breast cancer treatment

Patient Info: Anonymized, Female, 70+

Biopsies of the later chronic breast wound repeatedly showed no malignancy.

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Colorectal Cancer: Lily's Survivor Story

Patient Info: Lily, Under 40

She is now in remission and continues to manage health anxiety and the emotional effects of having cancer as a teenager.

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Delayed adrenal insufficiency after lung cancer immunotherapy

Patient Info: Anonymized, male, 60s | Stage II

Imaging and bronchoscopy in November 2024 showed no lung-cancer recurrence or metastasis. By June 2026, he had not experienced another adrenal crisis while continuing hormone replacement.

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Early-stage ovarian squamous cell carcinoma arising in a mature cystic teratoma

Patient Info: Anonymized, female, 50s | Stage I

Biomarkers: ovarian tumor HPV DNA-negative; p16-negative

She achieved complete remission and had no evidence of recurrence 24 months after surgery, at follow-up in June 2026.

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More than 5 years living with metastatic lung adenocarcinoma after stepwise molecular testing

Patient Info: Anonymized, Female, 50s | Stage IV

Biomarkers: HER2 amplification, EGFR L858R mutation, PD-L1 <1%

Metastatic Site: brain, lung

As of April 2026, she remained on gefitinib with no active tumor lesions after complete regression of lung metastases, more than 5 years (66 months) after her original diagnosis.

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Severe abdominal wall pain during advanced recurrent colon cancer

Patient Info: Anonymized, Female, 50s | Stage IV

Metastatic Site: peritoneum

She was living with recurrent advanced colon cancer with peritoneal metastasis and had transitioned to best supportive and palliative pain care.

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Complete response after chemotherapy for metaplastic breast cancer

Patient Info: Anonymized, Female, 50s

Biomarkers: ER-negative; weak PR-positive; HER2-negative

Surgery found no residual invasive or in situ breast cancer, and all 3 sentinel lymph nodes were negative, confirming a pathologic complete response.

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Hereditary diffuse gastric cancer with a CDH1 mutation and a separate gallbladder cancer

Patient Info: Anonymized, female, 60s | Stage I

Biomarkers: Pathogenic germline CDH1 mutation

A 67-year-old woman with multiple small signet-ring gastric cancers underwent total gastrectomy and was found to carry a pathogenic germline CDH1 mutation.

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Radiation-related morphea years after breast cancer treatment

Patient Info: Anonymized, Female, 50s

Biomarkers: ER-positive; PR-positive; HER2-negative

At follow-up in March 2026, more than 10 years after her breast cancer diagnosis, she remained free of oncologic recurrence and had completed 10 years of tamoxifen.

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Colorectal Cancer: Lorna's Patient Story

Patient Info: Lorna Brunelle, Female, 50s

Completed chemotherapy and surgery and continues oncology follow-up while using her experience to advocate for colorectal screening.

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Stage IV HER2-Positive Breast Cancer: Tiffany's Patient Story

Patient Info: Tiffany Andrews, Female, Under 40 | Stage IV

Biomarkers: HER2-positive; ER-negative at recurrence

Metastatic Site: lungs|brain

Tiffany is living with metastatic HER2-positive breast cancer and continues treatment through a clinical trial after progression in the lungs and brain.

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Triple-Negative Breast Cancer: Halassy's Survivor Story

Patient Info: Halassy, Female, 50s

Biomarkers: triple-negative

In remission for 45 months after surgery for the recurrent tumor.

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Stage III Invasive Lobular Carcinoma: Betsy's Patient Story

Patient Info: Betsy | Stage III

Betsy continues long-term hormone therapy with anastrozole after almost 2 years of tamoxifen.

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Stage II Breast Cancer: Naomi's Patient Story

Patient Info: Naomi Arbel-Brodd, Female | Stage II

Twenty years after her 2006 diagnosis, she had returned to UT MD Anderson as a weekly volunteer supporting other women receiving breast cancer care.

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Stage IV MSI-High Colorectal Cancer: Cindy's Patient Story

Patient Info: Cindy Mette, Female | Stage IV

Biomarkers: MSI-high

Cindy’s tumor responded to the experimental Werner helicase inhibitor, with falling CEA levels and radiologic response. The response was continuing in 2025 while she remained on the clinical trial.

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HER2-Positive Breast Cancer Treatment Followed by Multiple Myeloma

Patient Info: Anonymized, female, 50s | Stage II

Biomarkers: ER-negative; PR-negative; HER2 3+; Ki-67 70%

Postoperative imaging showed no breast cancer recurrence or distant metastasis, and the breast cancer was described as stable when a separate multiple myeloma diagnosis was made.

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Breast cancer treatment changed after severe colitis

Patient Info: Anonymized, Female, 50s | Stage II

Biomarkers: HER2-positive, ER-negative, PR-negative

In April 2025, follow-up evaluation showed no evidence of breast cancer recurrence.

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Unexpected blood vessel connection found during lung cancer surgery

Patient Info: Anonymized, Female, 70+ | Stage I

She recovered from postoperative complications and remained clinically stable at 8-month follow-up.

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Stage III MSI-High Colorectal Adenocarcinoma: Briana's Survivor Story

Patient Info: Briana Ghbein, Under 40 | Stage III

Biomarkers: MSH2 mutation, dMMR/MSI-H

Postoperative pathology after her 2024 treatment showed no evidence of disease.

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Lung cancer first discovered after a small-bowel blockage

Patient Info: Anonymized, Male, 50s | Stage IV

Metastatic Site: jejunum|brain|bone

The cancer progressed to the brain and spine despite chemotherapy, and he was admitted to palliative care.

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Stage III Invasive Lobular Carcinoma: Famke's Survivor Story

Patient Info: Famke, Female, Under 40 | Stage III

Famke received surgery, chemotherapy and radiation and celebrated 5 years since diagnosis while continuing long-term hormone therapy.

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Monica Mendoza

Patient Info: Monica Mendoza, 40s | Stage IV

Metastatic Site: liver

Monica was continuing chemotherapy after major surgeries and liver-directed treatment for Stage IV colorectal cancer with liver metastases.

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Long-term lung cancer control after immunotherapy-related diabetes

Patient Info: Anonymized, Male, 70+ | Stage IV

Biomarkers: PD-L1 80%; EGFR, ALK, ROS1 and BRAF negative

Metastatic Site: brain|liver

After years of disease control off pembrolizumab, a new brain lesion appeared in December 2025 and was treated with focused radiation. He remained clinically stable under oncology follow-up.

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