Stage IV HER2-Positive Breast Cancer: Nina's Survivor Story

Patient Info: Nina, Female, Under 40 | Stage IV

Biomarkers: HER2-positive; broad hereditary genetic testing negative

Metastatic Site: spine

As of November 2024, Nina described being in a no-evidence-of-disease phase, while continuing treatment because of her Stage IV HER2-positive metastatic breast cancer history.

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Stage II Colorectal Cancer: Savannah's Survivor Story

Patient Info: Savannah Kaspar, Female, Under 40 | Stage II

Biomarkers: Lynch syndrome genetic testing negative

As of March 2024, Savannah had completed partial colectomy and 4 rounds of adjuvant chemotherapy for Stage II sigmoid colon cancer and had entered surveillance with bloodwork every 3 months.

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Stage IV ALK Lung Cancer: Matt's Survivor Story

Patient Info: Matt Hiznay, Male, Under 40 | Stage IV

Biomarkers: ALK mutation / ALK-positive

Metastatic Site: Not reported

As of November 2023, Matt was a 12-year survivor with Stage IV ALK-positive lung cancer in remission, no evidence of disease, and ongoing lorlatinib treatment.

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Stage III HR-Positive Breast Cancer: Sarah's Survivor Story

Patient Info: Sarah McDonald, Female, 40s | Stage III

Biomarkers: ER-positive; PR-positive; HER2-negative

Sarah was 10 years from diagnosis without a recurrence and described the breast cancer as successfully treated. She later paused hormone therapy, completed IVF and gave birth at age 48.

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Rare breast blood-vessel cancer (angiosarcoma) in a teenage girl

Patient Info: Anonymized, Female

Biomarkers: Testing for Li-Fraumeni syndrome and POT1 mutation was inconclusive; no inherited cancer predisposition was established

She remained in remission 3 years after diagnosis and continued annual MRI surveillance of the reconstructed and opposite breasts.

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Triple-Negative Breast Cancer: Lucy's Survivor Story

Patient Info: Lucy E., Female, Under 40

Biomarkers: BRCA1 mutation; triple-negative breast cancer

As of January 2023, Lucy had been told she was all-clear/cancer-free after chemotherapy, had undergone double mastectomy with staged reconstruction planning, and was continuing close oncology reviews every 3-4 months.

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Stage II Triple-Negative Breast Cancer: Lucy's Patient Story

Patient Info: Lucy, Female, Under 40 | Stage II

Biomarkers: BRCA1 mutation; triple-negative breast cancer

As of January 2023, Lucy had gone through fertility preservation, chemotherapy, and double mastectomy for Stage II grade 3 triple-negative breast cancer with BRCA1 mutation; no NED or recurrence status was stated.

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Stage III Breast Cancer: Katie's Survivor Story

Patient Info: Katie, Female, Under 40 | Stage III

Biomarkers: Hormone-sensitive breast cancer; specific receptor results not otherwise reported

As of December 2021, Katie had no evidence of cancer at the 5-year treatment mark after Stage III hormone-sensitive breast cancer treatment and later had twins after ovarian function returned.

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Stage II HR-Positive Invasive Ductal Carcinoma: Caitlin's Patient Story

Patient Info: Caitlin J., Female, Under 40 | Stage II

Biomarkers: ER-positive; PR-positive; BRCA-negative

As of July 2020, Caitlin had completed lumpectomy, AC chemotherapy, Taxol, and 33 radiation treatments for Stage IIB ER-positive, PR-positive IDC and was continuing monthly Lupron plus daily anastrozole.

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Breast Cancer: Alexandria's Patient Story

Patient Info: Alexandria, Female, Under 40

As of December 2019, Alexandria was receiving chemotherapy after single mastectomy and fertility preservation; no final outcome, stage, or biomarker status was stated.

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Breast Cancer: Brittney's Survivor Story

Patient Info: Brittney Rinella, Female, Under 40

As of August 2019, Brittney was cancer-free 4 years after breast cancer treatment with double mastectomy and 4 chemotherapy rounds plus goserelin injections to help preserve ovarian function; she later gave birth to her son.

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Breast Cancer: Heather's Survivor Story

Patient Info: Heather Kokinda, Female, Under 40

As of March 2018, Heather had completed chemotherapy and double mastectomy, had a clear scan before trying to conceive again, and had given birth to another daughter in July 2017.

Cleveland ClinicRead more →