Small cell lung cancer discovered after recurrent pneumothorax

This lung cancer diagnosis at a glance

Subtype
Small Cell Lung Cancer
Sex
male
Treatment
surgery, chemotherapy and radiation
Outcome
Cancer-Free / NED

Treatment course, step by step

  1. Underwent VATS upper-lobe wedge resection/bullectomy and talc pleurodesis during treatment of recurrent pneumothorax, which established the cancer diagnosis.
  2. Received 4 cycles of carboplatin plus etoposide.
  3. Received prophylactic cranial irradiation.

What happened, in summary

A 62-year-old man with COPD and a heavy past smoking history presented twice within 2 months with a left-sided spontaneous pneumothorax. The second episode caused a persistent air leak, prompting referral for thoracic surgery. He underwent video-assisted upper-lobe wedge resection and bullectomy with talc pleurodesis. The resected tissue unexpectedly contained a 20 mm small cell lung carcinoma beneath a pleural defect. Further imaging, including brain MRI, did not show distant spread, and the cancer was described as limited-stage small cell carcinoma. After multidisciplinary review, he received 4 cycles of carboplatin plus etoposide followed by prophylactic cranial irradiation. A later chest CT showed only postsurgical changes and no evidence of tumor. He was doing well and remained under oncology follow-up. His cancer was discovered because recurrent pneumothoraces led to surgery, rather than through a typical lung-cancer symptom or screening pathway.

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This is a lay summary of an account first published by PMC / PubMed Central. Read the original in full

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