Stage IV signet-ring gastric cancer first presents with painful skeletal muscle metastases

This gastric cancer diagnosis at a glance

Stage at diagnosis
Stage IV
Subtype
Adenocarcinoma
Sex
Male
Spread to
skeletal muscle
Treatment
palliative care
Outcome
In Memory

Treatment course, step by step

  1. FOLFIRI chemotherapy was planned but was not started because his condition deteriorated rapidly.
  2. Received supportive palliative care only.

What happened, in summary

A 67-year-old man was admitted in March 2013 with a painful swelling in his thigh. Imaging showed abnormal areas in the gluteal and thigh muscles, and biopsy of the left gluteal muscle revealed metastatic signet-ring cell adenocarcinoma. Endoscopy then found an ulcerated lesion in the gastric antrum, where biopsy confirmed signet-ring cell gastric adenocarcinoma.

The muscle metastasis established Stage IV gastric cancer. A multidisciplinary team planned FOLFIRI chemotherapy, but his condition deteriorated quickly before treatment could begin. Within 2 months, he had developed widespread metastatic disease.

Because of the rapid progression and poor clinical condition, radiotherapy and surgery were not feasible. He received supportive palliative care only and died of the disease in June 2013, about 3 months after his initial presentation.

Where this story comes from

This is a lay summary of an account first published by PMC / PubMed Central. Read the original in full

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