Rectal adenocarcinoma causing severe secretory diarrhea and kidney failure

This colorectal cancer diagnosis at a glance

Subtype
Adenocarcinoma
Sex
Male
Treatment
surgery

Treatment course, step by step

  1. Underwent attempted piecemeal polypectomy after stabilization from renal failure.
  2. Persistent high-volume mucus secretion led to open abdominoperineal resection of the rectum.
  3. No adjuvant therapy was recommended.

What happened, in summary

A 79-year-old man was admitted after more than a year of profuse mucus secretion and watery diarrhea, which had worsened to as many as 10 episodes per day. He developed severe dehydration, electrolyte disturbance and acute kidney failure that required intensive care and emergency dialysis.

Imaging and colonoscopy showed a large rectal villous tumor. Initial biopsies found high-grade dysplasia, and a less invasive piecemeal polypectomy was attempted after his condition stabilized. The mucus loss continued, so the care team proceeded with an open abdominoperineal resection.

Final pathology showed a 9-centimeter villous adenoma containing a small Grade 1 adenocarcinoma with superficial submucosal invasion. The resection margins were clear and no lymph-node metastases were found. The oncology team recommended surveillance rather than adjuvant treatment. He recovered smoothly, was discharged on postoperative day eight, and had substantial improvement in strength and quality of life during the first month after surgery.

Where this story comes from

This is a lay summary of an account first published by PMC / PubMed Central. Read the original in full

How we source and attribute stories Accuracy and limitations

Collections this story belongs to

Similar colorectal cancer stories

These are lay summaries of published cancer stories, for information only. No two cancers behave the same way, and nothing here predicts your own diagnosis or replaces advice from your oncology team. Read the full disclaimer

Search more colorectal cancer stories