Stage IV cecum cancer with liver and ovarian metastases: ramucirumab-related nephrotic syndrome and glomerular microangiopathy

Patient Info: Anonymized, Female, 50s | Stage IV

Biomarkers: Cancer biomarkers were not reported. Kidney injury workup showed severe protein leakage and biopsy-proven glomerular microangiopathy.

Metastatic Site: liver, right ovary

The liver metastasis shrank after XELOX plus bevacizumab and metastatic liver/ovarian sites were resected, but ramucirumab-based second-line therapy was stopped after nephrotic syndrome and severe glomerular microangiopathy; blood pressure and proteinuria improved with telmisartan.

PubMed CentralRead more →

Stage IV Colorectal Adenocarcinoma: Lindy's Patient Story

Patient Info: Lindy Avalos, Female, Under 40 | Stage IV

Metastatic Site: lymph nodes, liver, lungs

As of December 2024, Lindy was on maintenance chemotherapy after 6 months of oxaliplatin and said she had been responding fairly well, though she was still living with Stage IV disease.

The Patient StoryRead more →

Colon cancer recurring in the spleen with a serious splenic abscess

Patient Info: Anonymized, Male, 40s | Stage IV

Biomarkers: KRAS wild-type, NRAS wild-type, BRAF wild-type

Metastatic Site: spleen

More than 5 years after his 2016 colectomy, he was treated for metastatic recurrence. Disease was assessed as stable during systemic therapy, and he later recovered well after splenectomy for confirmed splenic metastasis.

PubMed CentralRead more →

Stage III Colorectal Cancer: Jose's Survivor Story

Patient Info: Jose Santos, Male, 40s | Stage III

As of December 2024, more than 2 years after surgery for Stage III colorectal cancer, Jose had no evidence of disease, had adapted well to his ileostomy, and no longer had ulcerative colitis symptoms.

City of HopeRead more →

Stage IV KRAS Colorectal Cancer: Lauren's Patient Story

Patient Info: Lauren Bimage, Female, Under 40 | Stage IV

Biomarkers: Patient-reported KRAS-mutated colon cancer

Metastatic Site: chest; abdominal/peritoneal lining; spine/back

As of September 2024, Lauren was living with both Stage IV breast cancer and Stage IV colon cancer. Colon cancer markers were described as low/normal, while biopsy showed the persistent back/spine disease was breast cancer.

The Patient StoryRead more →

Stephanie’s Stage 3 Colon Cancer Story

Patient Info: Stephanie, Female, Under 40 | Stage III

CT and PET imaging after treatment showed no active colon cancer. Her October 2023 scans were clear and her oncologist described the cancer as in remission; unchanged spots in the liver and lung continued to be monitored.

The Patient StoryRead more →

Stage IV Colorectal Adenocarcinoma: Nick's Patient Story

Patient Info: Nick Sprague, Male, 40s | Stage IV

Metastatic Site: distant lymph nodes in abdomen/near aorta and left…

As of July 2024, Nick was living with Stage IVA colon cancer and receiving Keytruda/pembrolizumab with fewer side effects than chemotherapy; no NED status had been reached.

The Patient StoryRead more →

Stage IV Colorectal Adenocarcinoma: Elizabeth's Survivor Story

Patient Info: Elizabeth Wachsberg, Female | Stage IV

Metastatic Site: liver

As of July 2024, Elizabeth was 5 years cancer-free after Stage IV colon cancer with liver metastases, chemotherapy, and surgery.

The Patient StoryRead more →

Stage IV BRAF Colorectal Cancer: Sophie's Survivor Story

Patient Info: Sophie, Female | Stage IV

Biomarkers: BRAF-mutated; MSI / microsatellite instability

Metastatic Site: liver; lymph nodes including neck

As of June 2024, Sophie had been off treatment for nearly 3 years and described herself as currently cancer-free after surgery, chemotherapy, immunotherapy, and liver surgery showing no cancer cells.

The Patient StoryRead more →

Stage IV Colorectal Cancer: Amy's Patient Story

Patient Info: Amy Nicole, Female, Under 40 | Stage IV

Metastatic Site: liver; lymph nodes near kidneys/retroperitoneal lymph…

As of June 2024, Amy was living with recurrent Stage IV colon cancer and was on an immunotherapy clinical trial that improved quality of life compared with chemotherapy, though she did not describe remission or NED.

The Patient StoryRead more →

Stage II Colorectal Cancer: Savannah's Survivor Story

Patient Info: Savannah Kaspar, Female, Under 40 | Stage II

Biomarkers: Lynch syndrome genetic testing negative

As of March 2024, Savannah had completed partial colectomy and 4 rounds of adjuvant chemotherapy for Stage II sigmoid colon cancer and had entered surveillance with bloodwork every 3 months.

MD AndersonRead more →

How I KNEW I Had COLON CANCER

Patient Info: Courtney, Female | Stage III

As of March 2024, Courtney was nearly 3 years in remission after surgery and adjuvant chemotherapy for Stage IIIA colorectal cancer, with follow-up every 6 months.

The Patient StoryRead more →

Stage IIIB to metastatic rectal cancer: setback and treatment journey

Patient Info: Justine, Female, Under 40 | Stage IV

Metastatic Site: Liver; lung

As of March 2024, Justine was living with metastatic rectal cancer involving liver and lung, described as treatable but not curable, after surgery, permanent ileostomy, IV chemotherapy, liver ablation, lung SBRT, and Y-90 liver radioembolization.

The Patient StoryRead more →

Stage IV Colorectal Cancer: Jim's Patient Story

Patient Info: Jim Bromwich, Male, Under 40 | Stage IV

Metastatic Site: Lung

As of January 2024, he had completed focused radiation to an isolated lung nodule and was awaiting follow-up scans; another tiny lung nodule was being monitored but was not PET-avid.

The Patient StoryRead more →

Colorectal cancer: using a blood test (ctDNA) to guide immunotherapy after surgery — Case 1

Patient Info: Anonymized, Male, 50s

Biomarkers: KRAS ; TMB 11 mutations/Mb; loss of MLH1 and PMS2; dMMR/MSI-H; germline multigene panel negative; ctDNA positive after surgery and chemotherapy

Pembrolizumab cleared ctDNA within about 3 months. After completing 1 year of immunotherapy, surveillance CT showed no evidence of disease and ctDNA remained negative.

PubMed CentralRead more →

Stage III Colorectal Adenocarcinoma: Marissa's Patient Story

Patient Info: Marissa | Stage III

Still in active treatment at the time of the story after surgery and chemotherapy, with 15 radiation sessions delivered in September 2025.

Our Cancer StoriesRead more →

Metastatic Colorectal Cancer With Leucovorin Hypersensitivity During Cetuximab-FOLFOX Treatment

Patient Info: Anonymized, female, 60s | Stage IV

Biomarkers: EGFR mutation detected; no KRAS, NRAS or BRAF mutations detected

Metastatic Site: lung

After 18 cycles of cetuximab plus FOLFOX, her metastatic colorectal cancer was stable and treatment continued with modifications for leucovorin hypersensitivity.

PubMed CentralRead more →

Stage IV Colorectal Cancer: Jeff's Patient Story

Patient Info: Jeff Williams, Male, 50s | Stage IV

Metastatic Site: Liver; lungs

As of December 2023, Jeff was living with recurrent Stage IV colorectal cancer, had recently developed more lung tumors, continued chemotherapy locally every 2 weeks, and returned to UT MD Anderson every 3 months for scans.

MD AndersonRead more →

Stage III Colorectal Cancer: Stephanie's Survivor Story

Patient Info: Stephanie, Female, Under 40 | Stage III

As of November 2023, Stephanie reported that her oncologist said her cancer was in remission after surgery and chemotherapy, with CT/lab follow-up and a PET scan for reassurance.

The Patient StoryRead more →

Stage III Colorectal Cancer: Barbara's Survivor Story

Patient Info: Barbara, Female, 40s | Stage III

As of November 2023, Barbara described herself as a colon cancer survivor in year 4 after surgery and chemotherapy, continuing surveillance scans and living with scan anxiety and lasting treatment effects.

The Patient StoryRead more →

Hidden colon cancer first discovered through a rare brain/nerve inflammation

Patient Info: Anonymized, Male | Stage II

At 1 year he was asymptomatic and off treatment, with no neurological deficits and a normal repeat PET scan.

PubMed CentralRead more →

My Stage 4 Colorectal Cancer Story: How I Never Lost Hope

Patient Info: Jason Randall, Male | Stage IV

Metastatic Site: Liver; lungs; bone/sacrum

As of June 2023, Jason had a negative Signatera test, CT scans showing 9 months with no evidence of disease, and about 2.5 years off chemotherapy after Stage IV colorectal cancer treatment and lung ablation.

The Patient StoryRead more →

Stage II Colorectal Cancer: Amanda's Survivor Story

Patient Info: Amanda, Female, Under 40 | Stage II

Biomarkers: Genetic mutations involving colon, kidney, and skin cancer risk were reported; specific genes were not named

As of May 2023, Amanda had completed surgery and chemotherapy for Stage IIA sigmoid colon cancer and was in close surveillance, with CT scans every 6 months, bloodwork every 3 months, colonoscopy follow-up, and normal cancer-marker bloodwork.

The Patient StoryRead more →

How I Found Out I had Colon Cancer: I Wrote Off All My Symptoms

Patient Info: Haley P., Female, Under 40 | Stage III

As of March 2023, Haley had completed surgery, CAPOX chemotherapy, and 3 years of daily recurrence-prevention trial pills, with ongoing low-touch trial follow-up and no active recurrence described.

The Patient StoryRead more →