ER Positive Breast Cancer: 247 Real Stories

247 stories match breast cancer and ER positive. 215 of them mention surgery.

Cancer Stories

MB
Breast Cancer

Metastatic Breast Cancer Presenting With Severe Pulmonary Hypertension

Patient Info: Anonymized, Female, Under 40 | Stage IV

Biomarkers: ER-positive; PR-positive.

Metastatic Site: bone; bone marrow

At seven months, she was doing well with a marked response on PET imaging, normalized right-heart pressures, and ongoing systemic treatment with palbociclib.

PubMed Central
OutcomeResponding Well
A patient, who was diagnosed with Invasive Ductal CarcinomaBreast Cancer

Breast Cancer Arising in Ectopic Tissue in the Armpit

Patient Info: Anonymized, Female, 40s

Biomarkers: ER positive; PR positive; HER2 negative

A 43-year-old woman’s presumed axillary cyst proved to be hormone-receptor-positive breast cancer arising in ectopic breast tissue.

PubMed Central
OutcomeNot reported
Cath, who was diagnosed with Stage II Breast CancerBreast Cancer

Stage II HR-Positive Breast Cancer: Cath's Survivor Story

Patient Info: Cath, Female, 60s | Stage II

Biomarkers: ER-positive; PR-positive; HER2-negative

Cath was declared cancer-free in June 2024 after Stage II luminal A ER-positive/PR-positive/HER2-negative breast cancer treated with surgery, radiation, and hormone therapy, though she continued to manage long-term side effects and recurrence fear.

Our Cancer Stories
OutcomeCancer-Free / NED
A patient, who was diagnosed with Invasive Lobular CarcinomaBreast Cancer

Splenectomy Reduced Transfusion Needs in Metastatic Lobular Breast Cancer

Patient Info: Anonymized, Female, 40s | Stage Metastatic/Advanced

Biomarkers: ER positive; PR positive; HER2 negative

Metastatic Site: skin|bone|bone marrow|spleen

She remained independent through her last oncology visit 18 months after splenectomy and died 1 month later.

PubMed Central
OutcomeIn Memory
A patient, who was diagnosed with Invasive Lobular CarcinomaBreast Cancer

Lobular Breast Cancer Spreading to an Eye Muscle

Patient Info: Anonymized, Female, 40s | Stage Metastatic/Advanced

Biomarkers: Hormone receptor-positive; HER2-negative; E-cadherin-negative; CK7-positive

Metastatic Site: bones|left superior oblique eye muscle

The eye-muscle metastasis entered complete local remission, while bone disease was stable after 6 months of weekly paclitaxel and denosumab.

PubMed Central
OutcomeStable Disease
A patient, who was diagnosed with Invasive Ductal CarcinomaBreast Cancer

Recurrent Breast Cancer Initially Mistaken for Organising Pneumonia

Patient Info: Anonymized, Female, 60s | Stage Metastatic/Advanced

Biomarkers: ER-positive and GATA3-positive atypical pleural-fluid cells

Metastatic Site: lungs

After 12 months of first-line hormone therapy for metastatic recurrence, she had significant clinical and radiological improvement and remained on treatment.

PubMed Central
OutcomeResponding Well
A patient, who was diagnosed with Stage IV Invasive Ductal CarcinomaBreast Cancer

Breast cancer recurrence involving the bladder and bones

Patient Info: Anonymized, Female | Stage IV

Biomarkers: Initial breast cancer: ER-positive, PR-positive, HER2-negative. Bladder metastasis: ER-positive, PR-negative, HER2 1+.

Metastatic Site: bladder, bone, rectosigmoid region, anorectal region

She died in October 2016 from pulmonary haemorrhage, 47 months after metastatic disease was diagnosed.

PubMed Central
OutcomeIn Memory
A patient, who was diagnosed with Stage IV Invasive Lobular CarcinomaBreast Cancer

Breast cancer spreading to the colon, rectum and peritoneal surfaces

Patient Info: Anonymized, Female, 60s | Stage IV

Biomarkers: Primary tumor: ER >80% positive; PR 50–60% positive; HER2 negative; E-cadherin positive. Later colorectal metastases: ER positive; PR negative; HER2 negative; CK7 positive; CK20 negative; CDX2 negative.

Metastatic Site: colon, rectum, peritoneum, diaphragm, liver, bowel,…

Metastatic breast cancer was subsequently confirmed in the colon and rectum, with later laparoscopic biopsies showing peritoneal and additional intra-abdominal metastatic disease.

PubMed Central
OutcomeSetback / Progression
A patient, who was diagnosed with Stage II Invasive Ductal CarcinomaBreast Cancer

Luminal A breast cancer growing over 1 year in a 76-year-old woman

Patient Info: Anonymized, Female, 70+ | Stage II

Biomarkers: ER positive; PR negative; HER2 negative; Ki-67 20%

She had recovered from surgery and completed radiotherapy about 4 months after the initial operation, with adjuvant hormonal therapy planned.

PubMed Central
OutcomeCare Ongoing
A patient, who was diagnosed with Stage IV Invasive Lobular CarcinomaBreast Cancer

Occult lobular breast cancer presenting as an orbital metastasis

Patient Info: Anonymized, Female, 60s | Stage IV

Biomarkers: ER positive; PR positive; HER2 negative; CK7 positive; CK CAM5.2 positive; E-cadherin negative

Metastatic Site: left orbit, bone

The orbital metastasis decreased with treatment and systemic disease remained controlled on hormonal therapy during 5 years of clinical follow-up.

PubMed Central
OutcomeResponding Well
A patient, who was diagnosed with Stage III Breast CancerBreast Cancer

Triple receptor-positive neuroendocrine breast cancer in a 32-year-old woman

Patient Info: Anonymized, Female, Under 40 | Stage III

Biomarkers: ER positive; PR positive; HER2 positive; neuron-specific enolase positive; synaptophysin positive

She was stable on follow-up and was receiving adjuvant chest-wall radiation plus systemic chemotherapy and trastuzumab-based therapy.

PubMed Central
OutcomeCare Ongoing
A patient, who was diagnosed with Stage IV Invasive Ductal CarcinomaBreast Cancer

Stage IV Breast Cancer With Long-Term Tumor Regression After Radiation Therapy

Patient Info: Anonymized, female, 60s | Stage IV

Biomarkers: HER2 positive

Metastatic Site: 8th thoracic vertebra

Follow-up showed near-complete regression of the breast tumor, resolution of the bone lesion, normal tumor markers, and a 2015 biopsy with no tumor cells. Follow-up showed no further recurrence, and she returned to work with good quality of life.

PubMed Central
OutcomeCancer-Free / NED
A patient, who was diagnosed with Stage IV Invasive Lobular CarcinomaBreast Cancer

Breast cancer returning 21 years later as a solitary parotid metastasis

Patient Info: Anonymized, Female, 70+ | Stage IV

Biomarkers: Parotid metastasis ER positive; PR positive; HER2 borderline by IHC but FISH 1.82

Metastatic Site: left parotid gland

More than 5 months after the parotid metastasis was diagnosed, the tumour had slightly decreased in size and her metastatic disease remained stable on endocrine therapy.

PubMed Central
OutcomeLiving With Cancer
A patient, who was diagnosed with Stage IV Invasive Ductal CarcinomaBreast Cancer

Breast cancer returning years later in the biceps muscle

Patient Info: Anonymized, Female, 60s | Stage IV

Biomarkers: ER positive

Metastatic Site: left biceps muscle

Her arm symptoms improved considerably after radiotherapy, and MRI 6 months later showed a significant decrease in the size of the biceps tumour.

PubMed Central
OutcomeResponding Well
A patient, who was diagnosed with Invasive Ductal CarcinomaBreast Cancer

Breast Cancer Detected by Biopsy Despite a False-Negative Contrast Mammogram

Patient Info: Anonymized, female, 50s

Biomarkers: estrogen receptor positive, progesterone receptor positive

The final pathology showed an 11 mm grade 2 invasive ductal carcinoma with negative sentinel nodes, and she remains well on routine clinical surveillance.

PubMed Central
OutcomeCare Ongoing
Mauriel, who was diagnosed with Breast CancerBreast Cancer

Breast Cancer: Mauriel's Survivor Story

Patient Info: Mauriel Davis, Female

Biomarkers: Triple-positive; estrogen receptor-positive

As of May 2016, Mauriel had completed chemotherapy and surgery, had a positive 6-month follow-up, was moving beyond monthly visits, and felt she was recovering well; no explicit cancer-free/NED status was stated.

Cleveland Clinic
OutcomeSurvivorship / Surveillance
A patient, who was diagnosed with Inflammatory Breast CancerBreast Cancer

Breast invasive ductal carcinoma with coexisting inflammatory myofibroblastic tumor: disease-free after mastectomy, TAC, and tamoxifen

Patient Info: Anonymized, Female, Under 40

Biomarkers: Breast cancer: ER/PR-positive with HER2 2+ and p53-positive. Separate inflammatory myofibroblastic tumor had ALK/vimentin/actin/S-100 markers.

As of August 2013, she remained disease-free 2 years after modified radical mastectomy, 6 courses of TAC chemotherapy, and tamoxifen.

PubMed Central
OutcomeCancer-Free / NED
A patient, who was diagnosed with Breast CancerBreast Cancer

ER/PR-positive mucinous breast cancer treated with mastectomy and tamoxifen

Patient Info: Anonymized, Female, Under 40

Biomarkers: ER-positive; PR-positive; HER2/neu not overexpressed; no pathogenic BRCA1 or BRCA2 mutations identified; chromosome 13q34 duplication

After radical right mastectomy with nipple and areola preservation followed by tamoxifen, she showed no evidence of local recurrence or metastasis of breast cancer.

PubMed Central
OutcomeCancer-Free / NED
A patient, who was diagnosed with Stage IV Breast CancerBreast Cancer

Stage IV ER/PR-positive mucinous breast cancer: long-term no evidence of disease after surgery, AFTV, radiation, CEF, and endocrine therapy

Patient Info: Anonymized, Female, 50s | Stage IV

Biomarkers: ER-positive; PR-positive; delayed-type hypersensitivity to AFTV became pseudo-positive after vaccination and remained pseudo-positive 5.4 years later

Metastatic Site: Th7 vertebra

More than 6 years after primary surgery, she remained well with no evidence of vertebral metastasis activity, new metastasis, or local recurrence.

PubMed Central
OutcomeCancer-Free / NED
A patient, who was diagnosed with Stage IV Invasive Ductal CarcinomaBreast Cancer

ER-positive breast cancer recurrence with renal metastasis inside angiomyolipoma

Patient Info: Anonymized, Female, 60s | Stage IV

Biomarkers: ER-positive; mammaglobulin-positive; e-cadherin-positive; GCDFP-15-positive; melan A positive in angiomyolipoma component

Metastatic Site: right subpectoral lymph node, left kidney

At 7 months after nephrectomy, she continued anti-estrogen hormonal therapy with no demonstrable progression of disease; surgical excision of the subpectoral lymph node was offered but declined.

PubMed Central
OutcomeCare Ongoing
A patient, who was diagnosed with Stage IV Breast CancerBreast Cancer

ER/PR-positive breast cancer with bilateral ovarian metastases controlled after oophorectomy and aromatase inhibitor

Patient Info: Anonymized, Female, 50s | Stage IV

Biomarkers: ER-positive; PR-positive; HER2-negative; CK7-positive; gross cystic disease fluid protein-15-positive; CK20-negative

Metastatic Site: bilateral ovaries

After bilateral oophorectomies and aromatase inhibitor therapy, pleural effusion resolved, CEA and CA 15-3 decreased below the normal upper limit, and she remained well with no further recurrence for 40 months.

PubMed Central
OutcomeCancer-Free / NED