Cancer Stories
Breast CancerHR-Positive Breast Cancer: LaShae's Patient Story
Patient Info: LaShae, Female, Under 40
Biomarkers: ER-positive; MammaPrint high-risk recurrence; 70-gene hereditary cancer panel negative
Breast CancerStage 3 breast cancer: pathologic complete response to neoadjuvant chemotherapy
Patient Info: Anonymized, Female, Under 40
Biomarkers: ER-positive, PR-negative, HER2-negative breast cancer with very high Ki-67. MammaPrint high-risk/basal type; hereditary testing negative.
Breast CancerStage III HR-Positive Invasive Lobular Carcinoma: Liz's Patient Story
Patient Info: Liz O'Riordan, Female, 40s | Stage III
Biomarkers: ER-positive; HER2-negative; PIK3CA mutation reported by patient
Breast CancerStage I HR-Positive Breast Cancer: Allison's Survivor Story
Patient Info: Allison Tierney, Female | Stage I
Biomarkers: ER-positive; PR-positive; HER2-positive
Breast CancerInvasive lobular breast cancer with isolated scalp metastasis: excision and endocrine therapy
Patient Info: Anonymized, Female, 50s | Stage IV
Biomarkers: Original breast tumor: ER-positive; PR-positive; scalp metastasis: CK7-positive; ER-positive; GCDFP-15 partially positive
Metastatic Site: scalp/skin
Breast CancerMetastatic Breast Cancer With Recurrent Severe Hypocalcemia During Treatment - Case 1
Patient Info: Anonymized, female, Under 40 | Stage IV
Biomarkers: ER-positive; PR-positive; HER2-negative
Metastatic Site: bone, liver, ovaries
Breast CancerStage II HR-Positive Invasive Ductal Carcinoma: Allison's Patient Story
Patient Info: Allison Tierney, Female | Stage II
Biomarkers: ER-positive; PR-positive; HER2-positive; CHEK2 mutation; BRCA1/2 negative
Breast CancerStage II HR-Positive Invasive Ductal Carcinoma: Dorian's Survivor Story
Patient Info: Dorian de Salvo, Female | Stage II
Biomarkers: ER-positive; PR-positive; HER2-positive
Breast CancerMetastatic hormone receptor-positive breast cancer with paraneoplastic eosinophilic fasciitis
Patient Info: Anonymized, Female, 70+ | Stage IV
Biomarkers: ER-positive; PR-positive; eosinophilia during paraneoplastic eosinophilic fasciitis flare
Metastatic Site: pelvis
Breast CancerMale Invasive Lobular Breast Cancer With a Pathogenic PALB2 Variant
Patient Info: Anonymized, male, 40s
Biomarkers: ER-positive; PR-positive; HER2 not amplified; pathogenic PALB2 variant
Breast CancerInvasive Lobular Carcinoma: Sally's Survivor Story
Patient Info: Sally Johnston, 70+
Biomarkers: Estrogen receptor-positive
Breast CancerBreast Cancer Endocrine Therapy Complicated by Acute Mesenteric Artery Thrombosis
Patient Info: Anonymized, female, 50s
Biomarkers: ER-positive
Breast CancerMetastatic invasive lobular breast carcinoma to pancreas: biliary stent and paclitaxel
Patient Info: Anonymized, Female, 40s | Stage IV
Biomarkers: Primary breast tumor was triple-negative. Pancreatic metastasis was ER-positive/GATA-positive
Metastatic Site: pancreas; coelio-mesenteric lymph nodes
Breast CancerPatient Info: Anonymized, Female, 40s | Stage II
Biomarkers: ER-positive; PgR/PR-positive; HER2-positive by FISH amplification; Ki-67 index 50%
Breast CancerBRCA2-Positive Breast Cancer in a Woman With Down Syndrome
Patient Info: Anonymized, female, Under 40 | Stage IV
Biomarkers: ER-positive, PR-negative, HER2-negative, germline BRCA2 pathogenic variant
Metastatic Site: lungs, bones
Breast CancerStage III Male Breast Cancer Responds to Chemotherapy, Surgery and Radiation
Patient Info: Anonymized, male, 70+ | Stage III
Biomarkers: ER-positive, PR-positive, HER2-negative
Breast CancerFive Years Without Breast Cancer Recurrence Despite a Markedly Elevated CA 15-3
Patient Info: Anonymized, female, 70+ | Stage I
Biomarkers: ER-positive, PR-positive, HER2-positive
Breast CancerBreast Cancer Recurs After a 19-Year Remission and Responds to Later Chemotherapy
Patient Info: Anonymized, female, 50s | Stage IV
Biomarkers: Initial tumor: PR-positive, ER-negative, HER2-negative. Recurrence: ER-positive, PR-negative
Metastatic Site: bones
Breast CancerMale Breast Cancer Controlled for Years Through Multiple Lines of Targeted and Endocrine Therapy
Patient Info: Anonymized, male, 70+ | Stage IV
Biomarkers: Initial tumor ER-positive, PR-positive, HER2-positive; later ER-positive, PR-negative, HER2-negative; PIK3CA mutation; germline BRCA1/2 negative
Metastatic Site: bones, pleura, liver
Breast CancerBreast Cancer Patient Avoids a Potential Supplement Interaction During Paclitaxel Treatment
Patient Info: Anonymized, female, 50s
Biomarkers: ER-positive, PR-positive
Breast CancerPatient Info: Anonymized, female, 70+ | Stage IV
Biomarkers: ER-positive, PR-negative, HER2-negative
Metastatic Site: liver, bones, lymph nodes, kidney, brain
Breast CancerHER2-Positive Breast Cancer: Susan's Survivor Story
Patient Info: Susan, Female, 70+
Biomarkers: 2021 breast cancer described as estrogen-positive and progesterone-positive; HER2 not reported. First breast cancer biomarker status not reported.
Breast CancerHER2-Positive Acantholytic Squamous Breast Cancer Responds Completely to Preoperative Therapy
Patient Info: Anonymized, female
Biomarkers: HER2-positive; postoperative residual in-situ disease ER-positive and PR-positive
Breast CancerStage II HR-Positive Invasive Lobular Carcinoma: Megan's Survivor Story
Patient Info: Megan Claire Chase, Female | Stage II
Biomarkers: ER-positive; PR-positive; HER2 not reported