BRCA1 Mutation: 51 Real Stories

51 stories match BRCA1 mutation. 48 of them mention surgery.

SI
Breast Cancer

Stage II Triple-Negative Breast Cancer: Chance's Survivor Story

Patient Info: Chance Osborne, Female, Under 40 | Stage II

Biomarkers: ER-negative; PR-negative; HER2-negative; BRCA1 mutation

As of March 2024, Chance Osborne was a young Stage II TNBC survivor with a BRCA1 mutation, sharing her experience with chemotherapy, double mastectomy recovery, and advocacy.

Dear Cancer, I'm Beautiful (LBBC)
OutcomeSurvivorship / Completed Treatment
Chantal, who was diagnosed with Stage II Breast CancerBreast Cancer

Stage II Triple-Negative Breast Cancer: Chantal's Survivor Story

Patient Info: Chantal, Female, Under 40 | Stage II

Biomarkers: Triple-negative breast cancer; BRCA1 mutation

As of December 2023, Chantal reported that she did not currently have cancer, was followed by medical oncology every 3-4 months, and used Signatera testing because tumor markers were not reliable for her.

The Patient Story
OutcomeCancer-Free / NED
April, who was diagnosed with Stage IV Breast CancerBreast Cancer

Stage IV Triple-Negative Breast Cancer: April's Patient Story

Patient Info: April Donaldson, Female, 40s | Stage IV

Biomarkers: Triple-negative breast cancer; BRCA1 positive

Metastatic Site: Lungs

As of September 2023, April was living with Stage IV metastatic triple-negative breast cancer in the lungs; scans were stable in February but showed growth again in July, and PARP inhibitor therapy was being planned.

The Patient Story
OutcomeSetback / Progression
Carol, who was diagnosed with Breast CancerBreast Cancer

BRCA1 Breast Cancer: Carol's Survivor Story

Patient Info: Carol Arnhart

Biomarkers: BRCA1 mutation

She had a complete pathologic response to breast chemotherapy and later reported no evidence of breast cancer.

MD Anderson
OutcomeCancer-Free / NED
Carol, who was diagnosed with Stage I Ovarian CancerOvarian Cancer

Stage I BRCA1 Ovarian Cancer: Carol's Survivor Story

Patient Info: Carol Arnhart | Stage I

Biomarkers: BRCA1 mutation

After staging surgery and 6 rounds of carboplatin and paclitaxel, she reported no evidence of ovarian cancer.

MD Anderson
OutcomeCancer-Free / NED
Lucy, who was diagnosed with Breast CancerBreast Cancer

Triple-Negative Breast Cancer: Lucy's Survivor Story

Patient Info: Lucy E., Female, Under 40

Biomarkers: BRCA1 mutation; triple-negative breast cancer

As of January 2023, Lucy had been told she was all-clear/cancer-free after chemotherapy, had undergone double mastectomy with staged reconstruction planning, and was continuing close oncology reviews every 3-4 months.

The Patient Story
OutcomeCancer-Free / NED
Lucy, who was diagnosed with Stage II Breast CancerBreast Cancer

Stage II Triple-Negative Breast Cancer: Lucy's Patient Story

Patient Info: Lucy, Female, Under 40 | Stage II

Biomarkers: BRCA1 mutation; triple-negative breast cancer

As of January 2023, Lucy had gone through fertility preservation, chemotherapy, and double mastectomy for Stage II grade 3 triple-negative breast cancer with BRCA1 mutation; no NED or recurrence status was stated.

The Patient Story
OutcomeCare Ongoing
Janice, who was diagnosed with Breast CancerBreast Cancer

BRCA1 Breast Cancer: Janice's Patient Story

Patient Info: Janice Dolnick, female

Biomarkers: BRCA1 mutation

Janice had a 21-year history that included 2 rounds of breast cancer treatment and a bilateral mastectomy before a separate primary peritoneal cancer was diagnosed in 2018.

Dana-Farber
OutcomeNot reported
Mary, who was diagnosed with Breast CancerBreast Cancer

BRCA1 Breast Cancer: Mary's Patient Story

Patient Info: Mary Anne Marshall, female

Biomarkers: BRCA1 mutation

After the November 2017 double mastectomy, pathology showed clean margins and no lymph node invasion, and no additional breast cancer treatment was needed.

MD Anderson
OutcomeNot reported
Mary, who was diagnosed with Ovarian CancerOvarian Cancer

BRCA1 Ovarian Cancer: Mary's Patient Story

Patient Info: Mary Anne Marshall, female

Biomarkers: BRCA1 mutation

She completed a difficult 2-year ovarian cancer treatment course and was alive 4 years into her combined cancer journey.

MD Anderson
OutcomeNot reported
Muriel, who was diagnosed with Breast CancerBreast Cancer

BRCA1 Breast Cancer: Muriel's Survivor Story

Patient Info: Muriel Verger, Female, Under 40

Biomarkers: BRCA1 mutation

As of October 2021, Muriel described having completed about 9 months of treatment for triple-negative breast cancer diagnosed in 2015 and focused her message on survivorship, body image, and early detection.

YouTube (FR search)
OutcomeSurvivorship / Completed Treatment
Melanie, who was diagnosed with Breast CancerBreast Cancer

Triple-Negative Breast Cancer: Melanie's Survivor Story

Patient Info: Melanie Nix, Female, Under 40

Biomarkers: BRCA1 mutation; triple-negative breast cancer

Melanie remained cancer-free after treatment while continuing ongoing oncology monitoring because of her BRCA1 mutation and family history.

AACR
OutcomeCancer-Free / NED
Patty, who was diagnosed with Stage III Ovarian CancerOvarian Cancer

Stage III BRCA1 Ovarian Cancer: Patty's Patient Story

Patient Info: Patty Klein, Female | Stage III

Biomarkers: BRCA1 mutation

Patty was able to continue the olaparib plus BKM120 clinical trial as long as her tumor remained controlled. She later died.

AACR
OutcomeIn Memory
Roxana, who was diagnosed with Stage II Invasive Ductal CarcinomaBreast Cancer

Stage II BRCA1 Invasive Ductal Carcinoma: Roxana's Patient Story

Patient Info: Roxana Lopez, female, Under 40 | Stage II

Biomarkers: BRCA1 positive

After chemotherapy and bilateral mastectomy, Roxana continued regular screening for breast, ovarian and pancreatic cancers and melanoma.

MD Anderson
OutcomeCare Ongoing
Barb, who was diagnosed with Stage II Ovarian CancerOvarian Cancer

Stage II BRCA1 Ovarian Cancer: Barb's Patient Story

Patient Info: Barb White, female, 50s | Stage II

Biomarkers: BRCA1 mutation

Barb completed chemotherapy in June 2014 and later described being able to move forward after treatment.

MD Anderson
OutcomeNot reported
Nadine, who was diagnosed with Non-Small Cell Lung CancerLung Cancer

BRCA1 Non-Small Cell Lung Cancer: Nadine's Survivor Story

Patient Info: Nadine Beech, Female, Under 40

Biomarkers: Germline BRCA1 mutation for hereditary breast/ovarian cancer risk; lung cancer biomarker not reported

As of November 2016, Nadine was cancer-free after right bilobectomy for recurrent non-small cell lung cancer, following 19 years of lung cancer management that included left lower lobectomy, surveillance, Tarceva, and risk-reducing surgery for germline BRCA1.

MD Anderson
OutcomeCancer-Free / NED
OC
Ovarian Cancer

Ovarian Cancer With Severe Dermatomyositis During Treatment

Patient Info: Anonymized, female, 60s | Stage III

Biomarkers: BRCA1 mutation

She continued paclitaxel and carboplatin while being treated for severe dermatomyositis and later described herself as finally on the mend.

PubMed Central
OutcomeCare Ongoing
Mariana, who was diagnosed with Stage II Breast CancerBreast Cancer

Stage II BRCA1 Breast Cancer: Mariana's Patient Story

Patient Info: Mariana Torrado, female, Under 40 | Stage II

Biomarkers: BRCA1 positive

After breast cancer treatment and reconstruction, the patient described herself as a breast cancer survivor and was returning to normal activities.

MD Anderson
OutcomeNot reported
Meredith, who was diagnosed with Stage III Ovarian CancerOvarian Cancer

Stage III BRCA1 Ovarian Cancer: Meredith's Survivor Story

Patient Info: Meredith Ippolito, female | Stage III

Biomarkers: BRCA1 mutation

Meredith was told she was cancer-free in April 2009 and continued follow-up visits every 6 months.

MD Anderson
OutcomeCancer-Free / NED
A patient, who was diagnosed with Invasive Ductal CarcinomaBreast Cancer

BRCA1-associated right invasive ductal carcinoma followed by left acinic cell carcinoma of the breast

Patient Info: Anonymized, Female, 40s

Biomarkers: Constitutional BRCA1 mutation. Right breast cancer was ER/PR positive, HER2 negative; later left tumor was triple-negative with TP53 change.

After treatment for right invasive ductal carcinoma and later contralateral acinic cell carcinoma, she was alive and well 19 months after the acinic cell carcinoma surgery, with no evidence of disease while continuing hormonal therapy.

PubMed Central
OutcomeCancer-Free / NED