Radiation pneumonitis during chemoradiotherapy for Stage III squamous lung cancer

This lung cancer diagnosis at a glance

Stage at diagnosis
Stage III
Subtype
Squamous Cell Carcinoma
Sex
Male
Treatment
chemotherapy and radiation

Treatment course, step by step

  1. Received radical chemoradiotherapy with weekly carboplatin.
  2. Developed radiation pneumonitis and improved after corticosteroid treatment.

What happened, in summary

An 88-year-old man presented with coughing up blood and was diagnosed with Stage III squamous cell lung cancer. Imaging showed a 64-mm tumor in the right lower lobe with right hilar and mediastinal lymph-node involvement.

He received radical chemoradiotherapy with weekly carboplatin. About a month into treatment, he developed a cough before chest radiography showed a new lesion. By day 60, he had a fever and imaging showed bilateral ground-glass changes confined to the previously irradiated region. He was diagnosed with radiation pneumonitis.

Prednisolone was started and the lung changes improved. Serial breath-sound monitoring had shown a marked rise in fine crackles before the pneumonitis was diagnosed, followed by a decline after steroid treatment began.

Where this story comes from

This is a lay summary of an account first published by PMC / PubMed Central. Read the original in full

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