Stage III squamous lung cancer with a postoperative bronchopleural fistula that resolved with treatment

This lung cancer diagnosis at a glance

Stage at diagnosis
Stage III
Subtype
Squamous Cell Carcinoma
Sex
male
Treatment
chemotherapy, immunotherapy and surgery
Outcome
Cancer-Free / NED

Treatment course, step by step

  1. Received 2 cycles of neoadjuvant immunochemotherapy with a partial response.
  2. Underwent right middle and lower lobectomy.
  3. Received postoperative adjuvant therapy.

What happened, in summary

A 62-year-old man with Stage III squamous cell lung cancer received 2 cycles of neoadjuvant immunochemotherapy and achieved a partial response. He underwent removal of the right middle and lower lung lobes and later received postoperative adjuvant treatment. Two days after the first adjuvant cycle, he developed shortness of breath, cough and fever. CT imaging showed a bronchopleural fistula at the bronchial stump. About a week of anti-infective treatment substantially improved his symptoms, and later imaging showed that the fistula had resolved. He continued regular CT surveillance every 3 months without maintenance cancer treatment. No lung-cancer recurrence was seen during the follow-up described.

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This is a lay summary of an account first published by PMC / PubMed Central. Read the original in full

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