What happened, in summary

A 59-year-old man with Stage III squamous cell lung cancer received 3 cycles of neoadjuvant immunochemotherapy and achieved a partial response. He then underwent a left pneumonectomy, followed by one cycle of adjuvant immunochemotherapy and one cycle of sintilimab maintenance. Months later, cough and sputum returned. Imaging and bronchoscopy identified a small bronchopleural fistula in the left main bronchus. Because treatment options were limited, the fistula was repaired bronchoscopically with an occluder device. Follow-up imaging showed that the fistulous tract had closed. He remained off maintenance cancer treatment and continued CT surveillance every 3 months. More than 1 year into follow-up, there was no recurrence of the lung cancer.