What happened, in summary

A 43-year-old woman was diagnosed with Stage III lung adenocarcinoma. Testing for EGFR, ALK, KRAS, RET and ROS1 alterations was negative. She received 2 cycles of neoadjuvant immunochemotherapy and achieved a partial response, then underwent right upper lobectomy. She later received 2 cycles of postoperative adjuvant treatment. After the second cycle she developed fever, and CT imaging showed a bronchopleural fistula at the bronchial stump. Her symptoms gradually improved during 3 weeks of anti-infective treatment, and later imaging no longer showed a connection between the bronchus and pleural cavity. She continued CT surveillance every 3 months without maintenance cancer therapy. More than 1 year into follow-up, there was no recurrence of her lung cancer.