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An 80-year-old man underwent endoscopic treatment in 2005 for an early gastric cancer. The first lesion was a 10-mm well-differentiated adenocarcinoma confined to the stomach lining. It was removed by endoscopic submucosal dissection, and pathology showed clear margins with no lymphovascular involvement, meeting criteria for curative resection.
He then underwent annual endoscopic surveillance. Follow-up examinations showed no recurrence of this first cancer, and tumor-marker levels remained within the normal range.
About 2 years later, surveillance detected a separate 8-mm lesion in another part of the stomach. This was described as a metachronous gastric cancer rather than recurrence of the original tumor. The first cancer therefore remained without evidence of recurrence after its endoscopic removal, while the later gastric primary developed as a distinct cancer journey.
This is a lay summary of an account first published by PMC / PubMed Central. Read the original in full
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